MADHU DYAVAIAH Associate Professor

Profile Picture

  • Department of Biochemistry & Molecular Biology
  • School of Life Sciences
  • madhud14@yahoo.co.in

Academic Activity

Academic Activity Picture1

Academic Activity Picture2

Educational Qualification (UG,PG & Higher Order)

S.No Degree Subject/Title of thesis University/Board Year of Passing
1 PhD Biotechnology Mysore 2002
2 M.Sc Biotechnology Mysore 1995
3 B.Sc Chemistry, Botany & Zoology Mysore 1993

Area of Specializaion

Awards / Prizes Conferred

S.No Name / Title of the Award Type Name of the Agency conferred the Award Year of the Award Amount for Cash Award
1 Visiting Fellow NATIONAL Jawaharlal Nehru Center for Advanced Scientific Research (JNCASR), Bangalore 2020 50,000/Month for 3 m

Teaching Experience

S.No Designation Department/Centre Institution
1 Assistant Professor Biochemistry and Molecular Biology Pondicherry University
2 Lecturer Biotechnology T.John College, Banagalore University

Research Experience

S.No Designation Department/Centre Institution Area of Research
1 Research Associate Microbiology and cell biology Indian Institute of Science Bangalore Molecular Biology
2 Postdoctoral Fellow Wadsworth Center Dept. of Health, New York state, Albany, USA Molecular Pathogensis
3 Research Scientist Cancer Research Center University at Albany, New YORK, USA Cancer Research
4 Research Scientist Nanobioscience College of Nanoscale Science and Engeneering, Albany, USA Cancer Research

Industry Experience

S.No Designation Company/Corporate Nature of Work

Contribution towards Innovation

S.No Name of the Work/Contribution Specialization Remarks

Patent Details

S.No Title Status Patent Number Year of Award Type Commercialized Status

Papers Published in UGC Approved Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor

Papers Published in Non UGC Approved Peer Reviewed Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 In vivo, in vitro and molecular docking studies reveal the anti-virulence property of hispidulin against Pseudomonas aeruginosa through the modulation VT Anju, Siddhardha Busi, Mahima S Mohan, Sampathkumar Ranganathan, Dinakara Rao Ampasala, Ranjith Kumavath, Madhu Dyavaiah International Biodeterioration & Biodegradation 174, 1-10 2022 4.907
2 Metagenomic insights into taxonomic, functional diversity and inhibitors of microbial biofilms Madangchanok Imchen, VT Anju, Busi Siddhardha, Mahima S Mohan, Pattnaik Subhaswaraj, Madhu Dyavaiah, Ranjith Kumavath Microbiological Research 265, 1-17 2022 5.415
3 Alantolactone modulates the production of quorum sensing mediated virulence factors and biofilm formation in Pseudomonas aeruginosa VT Anju, Siddhardha Busi, Sandeep Kumar, Kitlangki Suchiang, Ranjith Kumavath, Sampathkumar Ranganathan, Dinakara Rao Ampasala, Madhu Dyavaiah Biofouling 38(4)331-347 2022 3.2
4 Oxidative stress alleviating potential of galactan exopolysaccharide from Weissella confusa KR780676 in yeast model system Digambar Kavitake, Bhavana Veerabhadrappa, SJ Sudharshan, Sujatha Kandasamy, Palanisamy Bruntha Devi, Madhu Dyavaiah, Prathapkumar Halady Shetty Scientific Reports 12(1), 1-15 2022 4.379
5 Repositioning antispasmodic drug Papaverine for the treatment of chronic myeloid leukemia Phani Krishna Parcha, Sailu Sarvagalla, Cheemala Ashok, S. J. Sudharshan, Madhu Dyavaiah, Mohane Selvaraj Coumar & Baskaran Rajasekaran Pharmacological Reports 73, 615–628 2021 2.754
6 Bacterial biofilm inhibition: A focused review on recent therapeutic strategies for combating the biofilm mediated infections Ramanathan Srinivasan, Sivasubramanian Santhakumari, Pandurangan Poonguzhali, Mani Geetha, Madhu Dyavaiah, Lin Xiangmin Frontiers in Microbiology 12 (5) 1106-1125 2021 4.07
7 Sesamin and sesamolin rescues Caenorhabditis elegans from Pseudomonas aeruginosa infection through the attenuation of quorum sensing regulated virulen VT Anju, Siddhardha Busi, Sampathkumar Ranganathan, Dinakara Rao Ampasala, Sandeep Kumar, Kitlangki Suchiang, Ranjith Kumavath, Madhu Dyavaiah Microbial Pathogenesis 155(7), 104912-104926 2021 3.738
8 [HTML] from oup.com Full View Evaluating the genetic basiss of anti-cancer property of Taxol in Saccharomyces cerevisiae model Bhavana Veerabhadrappa, Subasri Subramanian, Sudharshan SJ, Madhu Dyavaiah FEMS Microbiology Letters 368(13), 77-87 2021 2.742
9 Biogenic Silver Nanoparticles Decorated with Methylene Blue Potentiated the Photodynamic Inactivation of Pseudomonas aeruginosa and Staphylococcus aur Paramanantham Parasuraman, Thamanna R Y, Chitra Shaji, Alok Sharan, Ali H Bahkali, Helal F Al-Harthi, Asad Syed, VT Anju, Madhu Dyavaiah, Busi Siddhardha Pharmaceutics 29;12(8):709 2020 4.845
10 Astaxanthin protects oxidative stress mediated DNA damage and enhances longevity in Saccharomyces cerevisiae Sudharshan SJ, and Madhu Dyavaiah Biogerontology 2020 Oct 27. doi: 10.1007/s10522-020-09904-9. Online ahead of print. 2020 3.77
11 Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases Rajasekharreddy Pala, V T Anju, Madhu Dyavaiah, Siddhardha Busi, Surya M Nauli Int J Nanomedicine 27;15:3741-3769. 2020 4.540
12 Protective effect of quercetin in combination with caloric restriction against oxidative stress‐induced cell death of Saccharomyces cerevisiae cells P. Alugoju L. Periyasamy M. Dyavaiah Letters in applied microbiology 3(5)1 2020 1.805
13 Magnolol protects Saccharomyces cerevisiae antioxidant-deficient mutants from oxidative stress and extends yeast chronological life span. Subasri Subramaniyan 1, Phaniendra Alugoju, Sudharshan Sj , Bhavana Veerabhadrappa, Madhu Dyavaiah FEMS Microbiol Lett. 1;366(8):65 2019 1.994
14 Astaxanthin enhances the longevity of Saccharomyces cerevisiae by decreasing oxidative stress and apoptosis Sudharshan SJ, Bhavana Veerabhadrappa, Subasri Subramaniyan, Madhu Dyavaiah FEMS yeast research 9 (1), 113 2019 2.210,
15 Astaxanthin supplementation reduces dichlorvos-induced cytotoxicity in Saccharomyces cerevisiae SJ Sudharshan, Subasri Subramaniyan, Greeshma Satheeshan, Madhu Dyavaiah 3 Biotech 9 (3), 88 2019 2.270
16 Determination of antioxidant potential of selected wild edible mushrooms in Saccharomyces cerevisiae model System Subhaswaraj P, Sairengpuii, Sudharshan S, Dyavaiah M, Siddhardha B International Journal of Medicinal Mushrooms DOI: 10.1615/IntJMedMushrooms.2018026531 2018 1.357
17 Quercetin enhances stress resistance in Saccharomyces cerevisiae tel1 mutant cells to different stressors 3. Phaniendra Alugoju, Latha Periyasamy and Madhu Dyavaiah. Journal of Food Science and Technology 55(4):1455-1466 2018 1.797
18 Quercetin Protects Yeast Saccharomyces cerevisiae pep4 Mutant from Oxidative and Apoptotic Stress and Extends Chronological Lifespan 4. Phaniendra Alugoju, Sudharshan Setra Janardhanshetty, · Subasri Subaramanian,· Latha Periyasamy and Madhu Dyavaiah. Current Microbiology 75(5):519-530 2018 1.373
19 Oncoyeasti: a web-based application to translate data obtained from Saccharomyces cerevisiae high-throughput drug screens into cancer therapeutics Gupta, Ruby Cayenne, Samir Dyavaiah, Madhu Srinivas, Pragnya Otohinoyi, David Talukdar, Debjyoti Halari, Moheem Halari, Chidambra Ramani, Ashok Yusuf, Joshua Chahal, Khushdeep Kaur, Rupinde F1000Research https://doi.org/10.12688/F1000RESEARCH.15168.1 2018 1.13
20 Evaluation of in vivo antioxidant potential of Syzygium jambos (L.) Alston and Terminalia citrina Roxb. towards oxidative stress response in Saccharom Jobina Rajkumari, Madhu Dyavaiah, SJ Sudharshan, Siddhardha Busi Journal of food science and technology 55 (11), 4432-4439 2018 1.849
21 Evaluation of antioxidant activity of Magnolol in Saccharomyces cerevisiae.  Subramaniyan S, Dyavaiah M Journal of Pharmacy and Pharmaceutical Sciences 10 (9)104-107. 2018 2.33
22 Determination of antioxidant activity of Hibiscus sabdariffa and Croton caudatus in Saccharomyces cerevisiae model system 5. Subhaswaraj P, Sowmya M, Bhavana V, Dyavaiah M, Siddhardha B. J Food Sci Technol 54 (9), 2728-2736 2017 1.797
23 Determination of antioxidant potential of Acacia nilotica leaf extract in oxidative stress response system of Saccharomyces cerevisiae 6. Subhaswaraj P, Sowmya M, Jobina R, Sudharshan S, Dyavaiah M, Siddhardha B Journal of the Science of Food and Agriculture 97(15):5247-5253 2017 2.463
24 Microbial Keratitis in Contact Lens Wearers Madhu Dyavaiah, Phaniendra. A and Sudharshan. SJ JSM Ophthalmololgy 3(3):1036 2015 00
25 A genome-based catalog of one-, two-, three-, four- and five codon combinations present in Saccharomyces cerevisiae genes SudheerTumu., AshishPatil.,William Towns., Madhu Dyavaiah.and Thomas J. Begley Database (oxford) 9:462-475 2012 3.179
26 Reprogramming of tRNA modifications controls the oxidative stress response by selective translation of ribosomal protein paralogs Clement T.Y. Chan,Yang Ling Joy Pang, Ramesh Babu, Madhu Dyavaiah,Thomas J. Begley and Peter C. Dedon Nature Communications 3;3:937 2012 12.124
27 Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications AshishPatil, Clement Chan., Madhu Dyavaiah John P. Rooney., Peter Dedon., Thomas J.Begley RNA Biology 9(7):990-1001 2012 4.841
28 Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response Ashish Patil, Madhu Dyavaiah, Fraulin Joseph, John P. Rooney, Clement T. Y. Chan, Peter C. Dedon and Thomas J. Begley Cell cycle 11(19):3656-65 2012 5.243
29 Alkylation sensitivity screens reveal a conserved cross-species functionome 8. David Svilar, Madhu Dyavaiah, Ashley R. Brown, Jiang-boTangb, Peter R. McDonald,Tong Ying Shun, Xiao-hong Wang, John S. Lazo, Ian F. Pollack, Thomas J. Begley and Robert W. Sobol Molecular Cancer Research 10(12):1580-96 2012 4.974

Papers Published in Conference Proceedings

S.No Title Name of the Authors as per the order in Paper Details of Conference Publication Page Nos. Year

Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Chapters in Books

S.No Title of the Chapters Name of the Authors Title of the Book Publisher Year ISBN No.
1 Phytobiome research: Recent trends and developments VT Anju, Madhu Dyavaiah, Busi Siddhardha Trends of Applied Microbiology for Sustainable Economy Academic Press 2022 978-0-323-91595-3
2 Effect of soil biofilms on ecological function and impact on soil properties VT Anju, Busi Siddhardha, Madhu Dyavaiah Microbes in Land Use Change Management Elsevier 2021 978-0-12-824448-7
3 Quorum Sensing as a Therapeutic Target in the Treatment of Chronic Wound Infections VT Anju, Madhu Dyavaiah, Busi Siddhardha Wound Healing Research Springer, Singapore 2021 ISBN: 978-981-16-2676-0
4 Applications of nanoscale particles in antimicrobial photodynamic therapy V.T. Anjua , Madhu Dyavaiah , and Busi Siddhardha Handbook on Nano biomaterials for therapeutic and diagnostic applications Elsevier,, Cambridge, MA , United States 2021 978-0-12-821013-0
5 Animal Models to Understand Host–Pathogen Interactions V. T. Anju, Busi Siddhardha and Madhu Dyavaiah Model organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery Springer Nature, Singapore 2020 978-981-15-1695-5
6 Model Organism and Antimicrobial Drug Discovery Jobina Rajkumari, Madhu Dyavaiah, Asad Syed and Busi Siddhardha Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery Springer Nature, Singapore 2020 978-981-15-1695-5
7 Nanostructures for Antimicrobial and Antibiofilm Photodynamic Therapy V. T. AnjuBusi Siddhardha and Madhu Dyavaiah Nanostructures for Antimicrobial and Antibiofilm Applications Springer International Publishing 2020 978-3-030-40337-9
8 Saccharomyces cerevisiae: Model Organism to Evaluate Nanoparticle Toxicity V. T. Anju, Busi Siddhardha and Madhu Dyavaiah Model Organisms to Study Biological Activities and Toxicity of Nanoparticles Springer, Singapore 2020 978-9811517013
9 Applications of Carbon-Based Nanomaterials for Antimicrobial Photodynamic Therapy Parasuraman Paramanantham, V. T. Anju, Madhu Dyavaiah and Busi Siddhardha Microbial Nanobionics Springer, Cham 2019 978-3-030-16533-8
10 Natural Anti-cancer Compounds and Their Derivatives in Clinical Trials Veerabhadrappa. Bhavana, Setra Janardhana Shetty Sudharshan, Dyavaiah Madhu Anticancer Plants: Properties and Applications Springer-Verlag GmbH Berlin Heidelberg 2018 9789811085475
11 Yeasts: Candida and Cryptococcus. Bacterial and mycotic infections Madhu Dyavaiah, Subasri and Geetha N. Prashanth immunocompromised hosts: Clinical and microbiological aspects Omics Group Incorporation, Nevada, USA 2013 978-1-63278-005-8
12 DNA Damage Response Research, Inherent and Future Nano-Based Interfaces for Personalized Medicine Madhu Dyavaiah, Endres, L. Hsieh, Y., Towns, W. and Begley, T. J. The Nanobiotechnology Handbook Boca Raton, FL, CRC Press 2012 9781138075856

Edited Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.
1 Nanostructures for Antimicrobial and Antibiofilm Applications Prasad, Ram, Siddhardha, Busi and Dyavaiah, Madhu Springer Nature Switzerland AG 2020 978-3-030-40337-9
2 Model Organisms to Study Biological Activities and Toxicity of Nanoparticles Siddhardha, Busi, Dyavaiah, Madhu and Kasinathan, Kaviyarasu Springer, Singapore 2020 978-981-15-1702-0
3 Model organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery Busi Siddhardha, Madhu Dyavaiah and Asad Syed Springer Nature, Singapore 2020 978-981-15-1695-5

Ongoing Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Yeast model to study the role of Astaxanthin in protecting oxidative DNA damage to alleviate age associated diseases in human DST-SERB, Govt. of India 2018-2021 37,49,600 2018

Ongoing Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Completed Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Trm9 - catalyzed tRNA modifications in regulating translational errors and ER stress UGC-BSR, Govt. of India 2013-2015 6 2013
2 Screening for molecular targets of anti-cancer drug using Saccharomyces cerevisiae UGC-MRP, Govt. of India 2013-2017 11.8 2013

Completed Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Career Guidance Offered to students

S.No Name of the Scheme No. of Students Competitive Examinations/ Career Counseling No. of Students Passed No. of Students Placed

List of capability enhancement such as Soft skill development, Remedial coaching, Language lab,
Bridge courses, Yoga, Meditation, Personal Counselling and Mentoring etc.,

S.No Name of the Programme/Scheme Date of Implementation No. of Students Enrolled Agencies Involved

Research Guidance - PG

S.No Year Degree No. of Students Awarded Department/Centre
1 2021 M.SC 4 Biochemistry and Molecular Biology
2 2020 M.SC 3 Biochemistry and Molecular Biology
3 2019 M.SC 3 Biochemistry and Molecular Biology
4 2018 M.SC 2 Biochemistry and Molecular Biology
5 2017 M.SC 2 Biochemistry and Molecular Biology
6 2016 M.SC 2 Biochemistry and Molecular Biology
7 2015 M.SC 2 Biochemistry and Molecular Biology
8 2014 M.SC 2 Biochemistry and Molecular Biology
9 2013 M.SC 5 Biochemistry and Molecular Biology

Research Guidance - Ph.D

S.No Student Name Registration Date Registration No. Thesis Title Thesis Submitted Status Thesis Submitted Date Vivavoce Completed Status Date Awarded
1 Subasri. S 06-08-2012 21354684 Evaluation of antioxidant, antiapoptotic and antiaging properties of magnolol in Saccharomyces cerevisiae YES 02-04-2019 YES 14-10-2020
2 Sudharshan. S. j 06-02-2013 245633654 Molecular Mechanism of astaxanthin in protecting the Saccharomyces cerevisiae cells from various stresses YES 09-04-2019 YES 26-09-2019
3 Greeshma 06-06-2017 21354636 Understanding the cyrotoxic properties of lycorine on translation dysregulated cells NO NO
4 ANJU V T 30-07-2019 1800102001 Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases NO NO
5 JEMIMA PRINCILLY A 03-09-2019 1900102005 Yeast model to study the role of Astaxanthin in protecting oxidative DNA damage to alleviate age associated diseases in human NO NO
6 Archana Jena 01-12-2021 2100102002 Targeting DNA repair deficient cells by lycorine for cancer therapy NO NO

Research Guidance - Post Doctoral

S.No Scholar Name Designation Funding Agency Fellowship Title Year of Joining Year of Completion
1 Santhakumari. S Postdoctoral Fellow DST-SERB DST-SERB - National Postdoctoral Fellow 03-06-2019 01-06-2021

Financial assistance availed to attend conferences / workshops and to pay membership fee
of professional bodies during the year

S.No Conference/ workshop attended for which financial support provided Professional body for which membership fee is provided Amount of Support Place From Date To Date Year

E-Lecture Details

S.No E-Lecture Title Development of e-content/e-learning/delivering Member of Editorial Bodies Reviewer/Referee of
Content/Module Title Institution/Platform Year Weblink

Details of Online Education Conducted

S.No Nature of Online Course No. of Sessions Target Group Date

Invited Talks in Conference/Seminar/Workshop/Training Programme

S.No Title of the Paper Conferences/Seminar/Workshop/Training Programme Organized by Whether International / National / State / Regional / College or University Level From To Year
1 Gene editing ethical and safety issue Conferences V.G. Shivdare College of Arts, Commerce and Science College, Sollapur National 20-10-2020 21-10-2020 2020
2 Job oppertunitis in life science Programme Theivanai Ammal College College 03-07-2019 03-07-2019 2019
3 Clinical Trails in Drug Discovery Work shop Dept. of Biochemistry and Molecular Biology Regional 03-12-2018 03-12-2018 2018
4 tRNA modification regulate translation of stress response genes Seminar Center for bioinformatics, Pondicherry University University level 15-11-2017 15-11-2017 2017
5 Heterologous protein expression and purification Workshop Dept of Microbiology, Pondicherry University, Pondicherry National 02-01-2015 17-01-2015 2016

Conferences/Seminars Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 National Science Day Seminar 2017 Pondicherry University Pondicherry University, 1-day National 24-02-2017 24-02-2017 2017
2 National Seminar on Drug Discovery and Cancer Therapy DBT, Govt. of India and Pondicherry Universtiy Pondicherry University, 2-days National 25-02-2016 26-01-2016 2016

Workshop Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year

Administrative Responsibilities in the Government and Quasi Government Agencies

S.No Name of the Position Agency/Organisation Duration Nature of Duties

Affiliation in Academic Bodies/Societies

S.No Name of the Body/Society Nature of Affiliation Year

Participation & Extension Activities (Academic/Administraion)

S.No Name of the Position (Head, Dean, Co-ordinator, Director, etc.,) Duration Nature of Dutites
1 UG/PG board of studies in Plant Sciences (Botany) member 2016-2019 Syllabus development

Participation & Extension Activities (Co-Curricular)

S.No Name of the Position (NSS, NCC, Warden etc.,) Duration Nature of Dutites

Collaboration with Institution/Industry

S.No Collaborator Name Designation Institution/Industry Type Nature of Collaboration Period of Collaboration Visits to Collaborating
Institution / Industry		 Details of Collaborative Research/Teaching
From Date To Date From Date To Date

Faculty Development Programme Attended (Orientation, Refresher, other Short Term Course during the year)

S.No Title of the FDP Organiser Venue Duration From Date To Date Year

Details of Executive Development Prog/Management Development Prog. conducted

S.No Name of the Programme No. of Participants Venue Duration From Date To Date Year Revenue Generated

Participation in IMPESS, IMPRINT, SPARC, STARS, LEAP Programme etc and DSF Funding Programme

S.No IMPRESS/IMPRINT/SPARC/STARS/LEAP/Others Place From Date To Date Year

Enrolment under ARPIT Programme

S.No Name of the Programme Period of the Programme
From Date To Date