MURALI. A Assistant Professor

Profile Picture

  • Department of Bioinformatics
  • School of Life Sciences
  • mayaluru@gmail.com

Academic Activity

Academic Activity Picture1

Academic Activity Picture2

Educational Qualification (UG,PG & Higher Order)

S.No Degree Subject/Title of thesis University/Board Year of Passing
1 Ph.D. Spectral Investigations on Certain Transition Metal and Rare-Earth Ions in Fluorophosphate, Borate and Borotellurite Glasses. Sri Venkateswara University, Tirupati - 517502 2000
2 M.Phil. Physics/EPR and Optical Absorption Studies on Vanadyl doped Alkali Tetraborate Glasses. Sri Venkateswara University, Tirupati - 517502 1996
3 M.Sc. Physics Sri Venkateswara University, Tirupati - 517502 1993

Area of Specializaion

Awards / Prizes Conferred

S.No Name / Title of the Award Type Name of the Agency conferred the Award Year of the Award Amount for Cash Award

Teaching Experience

S.No Designation Department/Centre Institution
1 Assistant Professor Centre for Bioinformatics Pondicherry University

Research Experience

S.No Designation Department/Centre Institution Area of Research
1 Research Associate School of Physics University of Hyderabad Characterization of amorphous materials
2 Post Doctoral Fellow Department of Chemistry University of Houston, Houston, TX 77204, USA. Synthesis and characterization of Mesoporous Materials
3 Post-Doctoral Research Associate Department of Chemistry Texas A&M University, College Station, TX 77842, USA. EPR studies of Spin Labeled RNA molecules
4 Post-Doctroal Research Associate Department of Biochemistry & Biophysics Texas A&M University, College Station, TX 77843, USA. Structural Biology, TEM, Single Particle Analysis
5 Post-Doctoral Research Associate Department of Biology Indiana University, Bloomington, IN 47403, USA. Structural Biology, TEM, Single Particle Analysis

Industry Experience

S.No Designation Company/Corporate Nature of Work

Contribution towards Innovation

S.No Name of the Work/Contribution Specialization Remarks

Patent Details

S.No Title Status Patent Number Year of Award Type Commercialized Status

Papers Published in UGC Approved Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 Chalcogenolato-bridged rhenium (I)-based ester functionalized flexible dinuclear metallacrown ethers: Cation binding, molecular recognition and dockin Udit Kumar, Shruti Verma, Adyasha Anindita Sahoo, Soumya Sree Samal, Jyotilipsa Mohanty, Ayaluru Murali, Bala Manimaran Polyhedron 226, 116084 (https://doi.org/10.1016/j.poly.2022.116084) 2022 2.975
2 Computational analysis of marine algal compounds for obesity management against pancreatic lipase Lavanya Prabhakar, Davis G Dicky John, Satya Ranjan Singh, Ayaluru Murali Journal of Biomolecular Structure and Dynamics 1-10 (https://doi.org/10.1080/07391102.2022.2074139) 2022 5.235
3 Molecular evaluation of quorum quenching potential of vanillic acid against Yersinia enterocolitica through transcriptomic and in silico analysis Chandran Sivasankar, Nisha Kumari Jha, Satya Rajan Singh, Ayaluru Murali, Prathapkumar Halady Shetty Journal of Medical Microbiology 69 (11), 1319-1331 (https://doi.org/10.1099/jmm.0.001261) 2020 2.156
4 2,4-Di-Tert-Butylphenol Isolated From an Endophytic Fungus, Daldinia eschscholtzii, Reduces Virulence and Quorum Sensing in Pseudomonas aeruginosa Rashmi Mishra, Jai Shanti Kushveer, Mohd Imran K Khan, Sudhakar Pagal, Chetan Kumar Meena, Ayaluru Murali, Arunkumar Dhayalan, Vemuri Venkateswara Sarma Frontiers in microbiology 11, 1668 (https://doi.org/10.3389/fmicb.2020.01668) 2020 6.064
5 Anti-quorum sensing and anti-biofilm activity of 5-hydroxymethylfurfural against Pseudomonas aeruginosa PAO1: Insights from in vitro, in vivo and in s Jobina Rajkumari, Subhomoi Borkotoky, Dhanasekhar Reddy, Saswat Kumar Mohanty, Ranjith Kumavath, Ayaluru Murali, Kitlangki Suchiang, Siddhardha Busi Microbiological research 226, 19-26 (https://doi.org/10.1016/j.micres.2019.05.001) 2019 5.07
6 Attenuation of quorum sensing controlled virulence factors and biofilm formation in Pseudomonas aeruginosa by pentacyclic triterpenes, betulin and bet Jobina Rajkumari, Subhomoi Borkotoky, Ayaluru Murali, Kitlangki Suchiang, Saswat Kumar Mohanty, Siddhardha Busi Microbial Pathogenesis Volume 118, 48-60 2018 2.009
7 Cinnamic acid attenuates quorum sensing associated virulence factors and biofilm formation in Pseudomonas aeruginosa PAO1. Jobina Rajkumari, Subhomoi Borkotoky, Ayaluru Murali, Kitlangki Suchiang, Saswat Kumar Mohanty, Siddhardha Busi Biotechnology Letters Volume 40, Issue 7, 1087–1100 2018 2.716
8 The highly efficient T7 RNA polymerase: A wonder macromolecule in biological realm. Subhomoi Borkotoky, Ayaluru Murali*. International Journal of Biological Macromolecules Volume 118, Part A, 49-56 2018 8.025
9 Anti-quorum sensing activity of Syzygium jambos (L.) Alston against Pseudomonas aeruginosa PAO1 and identification of its bioactive components J Rajkumari, S Borkotoky, A Murali, S Busi South African Journal of Botany 118, 151-157 (https://doi.org/10.1016/j.sajb.2018.07.004) 2018 3.111
10 Anti-quorum sensing and antibiofilm potential of Alternaria alternata, a foliar endophyte of Carica papaya, evidenced by QS assays and in-silico analy M Rashmi, Himani Meena, Chetan Meena, JS Kushveer, Siddhardha Busi, A Murali, VV Sarma Fungal biology 122 (10), 998-1012 (https://doi.org/10.1016/j.funbio.2018.07.003) 2018 2.91
11 A computational assessment of pH dependent differential interaction of T7 lysozyme with T7 RNA polymerase. Subhomoi Borkotoky, and Ayaluru Murali*. BMC Structural Biology Vol. 17, Article No.7, doi 10.1186/s12900-017-0077-9 2017 2.222
12 An in-silico glimpse into the pH dependent structural changes of T7 RNA polymerase: a protein with simplicity Subhomoi Borkotoky, Chetan Kumar Meena, Gopalkrishna M. Bhalerao and Ayaluru Murali*. Scientific Reports Vol. 7, Article number: 6290 2017 4.259
13 Modeling of alcohol oxidase enzyme of Candida boidinii and in silico analysis of competitive binding of proton ionophores and FAD with enzyme. Mohammad Wahab Khan, Ayaluru Murali*. Molecular BioSystems Vol. 13, 1754-1769 2017 2.92
14 Quorum quenching activity in the cell-free lysate of Enterobacter ludwigii isolated from beef and its effect on quorum sensing regulation in Yersinia Gopu, V.; Meena, C. K.; Murali, A.; Shetty, P. H. RSC Advances Volume 6, 21277-21284 2016 3.108
15 Interaction Analysis of T7RNA Polymerase with Heparin and its Low Molecular Weight Derivatives – An in silico Approach. Subhomoi Borkotoky, Chetan Kumar Meena, Ayaluru Murali*. Bioinformatics and Biology Insights Vol. 10, 155-166 2016 NA
16 Insight into virus encapsulation mechanism through in silico interaction study between coat protein and RNA operator loops of Sesbania mosaic virus. Meena C.K.; Borkotoky, S.; Murali, A*. Molecular BioSystems Vol. 12, 1996-2009 2016 2.92
17 Petunidin as a competitive inhibitor of acylated homoserine lactones in Klebsiella pneumoniae. Gopu, V.; Meena, C. K.; Murali, A.; Shetty, P. H. RSC Advances Vol. 6, 2592-2601 2016 3.108
18 Electron paramagnetic resonance and photoluminescence investigation on ultraviolet-emitting gadolinium-ion-doped CaAl(1)(2)O(1)(9) phosphors. Singh, V.; Borkotoky, S.; Murali, A.; Rao, J. L.; Rao, T. K.; Dhoble, S. J. Spectrochimica Acta Part A Molecular and biomolecular spectroscopy Vol. 139, 1-6 2015 2.098
19 Insight into the LGP2 Helicase Domain – An in Silico Approach. Subhomoi Borkotoky, Chetan Kumar Meena, Aswathy Soman, Ayaluru Murali*. International Journal of Biochemistry Biophysics Volume 3, Issue 2: 13-23 2015 NA
20 Acinetobacter phage genome is similar to Sphinx 2.36, the circular DNA copurified with TSE infected particles. Longkumer T, Kamireddy S, Muthyala VR, Akbarpasha S, Pitchika GK, Kodetham G, Murali A, Siddavattam D. Scientific Reports Volume 3, Article number: 2240 2013 4.259
21 Three dimensional electron microscopy and in silico tools for macromolecular structure determination. Borkotoky S, Meena CK, Khan MW, Murali A*. EXCLI Journal Vol. 12, 335–346. 2013 1.462
22 The Arabidopsis Stress Responsive Gene Database. Borkotoky S, Saravanan V, Jaiswal A, Das B, Selvaraj S, Murali A, Lakshmi PTV. International Journal of Plant Genomics Volume 2013, Article ID 949564, 3 pages 2013 NA

Papers Published in Non UGC Approved Peer Reviewed Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 pH-induced conformational changes in SP6 RNA polymerase: an in silico study Satya Ranjan Singh, Ayaluru Murali Journal of Science 5 (3), 2 2022 NA
2 Insight into the LGP2 Helicase Domain – An in Silico Approach Subhomoi Borkotoky, Chetan Kumar Meena, Aswathy Soman, Ayaluru Murali* International Journal of Biochemistry Biophysics Volume 3, Issue 2: 13-23 2015 NA

Papers Published in Conference Proceedings

S.No Title Name of the Authors as per the order in Paper Details of Conference Publication Page Nos. Year

Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Chapters in Books

S.No Title of the Chapters Name of the Authors Title of the Book Publisher Year ISBN No.

Edited Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Ongoing Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Ongoing Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Completed Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Structure of Qbeta replicase in different ionic strengths using single particle analysis University Grants Commission, New Delhi 2012-2015 14.25 2012

Completed Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Career Guidance Offered to students

S.No Name of the Scheme No. of Students Competitive Examinations/ Career Counseling No. of Students Passed No. of Students Placed

List of capability enhancement such as Soft skill development, Remedial coaching, Language lab,
Bridge courses, Yoga, Meditation, Personal Counselling and Mentoring etc.,

S.No Name of the Programme/Scheme Date of Implementation No. of Students Enrolled Agencies Involved

Research Guidance - PG

S.No Year Degree No. of Students Awarded Department/Centre
1 2022 M.SC 4 Bioinformatics
2 2022 M.TECH 3 Bioinformatics
3 2021 M.SC 3 Bioinformatics
4 2021 M.TECH 1 Bioinformatics
5 2020 M.SC 3 Bioinformatics
6 2020 M.TECH 1 Bioinformatics
7 2019 M.SC 3 Bioinformatics
8 2019 M.TECH 1 Bioinformatics
9 2018 M.TECH 1 Bioinformatics
10 2018 M.SC 3 Bioinformatics
11 2017 M.TECH 1 Bioinformatics
12 2017 M.SC 2 Bioinformatics
13 2016 M.TECH 1 Bioinformatics
14 2016 M.SC 2 Bioinformatics
15 2015 M.SC 3 Bioinformatics
16 2014 M.SC 3 Bioinformatics
17 2013 M.SC 3 Bioinformatics
18 2012 M.SC 4 Bioinformatics

Research Guidance - Ph.D

S.No Student Name Registration Date Registration No. Thesis Title Thesis Submitted Status Thesis Submitted Date Vivavoce Completed Status Date Awarded
1 SATYA RANJAN SINGH 31/07/2018 1800104009 NA NO NO
2 JYOTILIPSA MOHANTY 17/09/2018 1800104014 NA NO NO
3 LUKKANI LAXMAN KUMAR 05/08/2019 1900104003 NA NO NO
4 AHANA ROY CHOUDHURY 28/01/2021 2000104001 NA NO NO
5 Subhomoi Borkotoky 15/09/2011 R27352 Structural Investigations of T7 RNA Polymerase: Single Particle Analysis and Computational Approaches YES 13/03/2017 YES 18/12/2017
6 Chetan Kumar Meena 25/07/2012 R34504 In vitro and in silico study of genome encapsulation mechanism in Sesbania Mosaic Virus. YES 09/01/2018 YES 07/09/2018
7 Mohd. Wahab Khan 01/08/2012 R29253 Computational modeling, inhibition, intrinsic dynamics and protease interaction study of alcohol oxidase from Candida boidinii YES 24/01/2018 YES 02/07/2018

Research Guidance - Post Doctoral

S.No Scholar Name Designation Funding Agency Fellowship Title Year of Joining Year of Completion

Financial assistance availed to attend conferences / workshops and to pay membership fee
of professional bodies during the year

S.No Conference/ workshop attended for which financial support provided Professional body for which membership fee is provided Amount of Support Place From Date To Date Year

E-Lecture Details

S.No E-Lecture Title Development of e-content/e-learning/delivering Member of Editorial Bodies Reviewer/Referee of
Content/Module Title Institution/Platform Year Weblink

Details of Online Education Conducted

S.No Nature of Online Course No. of Sessions Target Group Date

Invited Talks in Conference/Seminar/Workshop/Training Programme

S.No Title of the Paper Conferences/Seminar/Workshop/Training Programme Organized by Whether International / National / State / Regional / College or University Level From To Year
1 Role of Functionalized Materials in Modern Biology National Seminar on Advanced Functional Materials D R W College, Gudur, AP National 04-03-2017 04-03-2017 2017
2 Role of separation methods of biomolecules in Structural Biology – the Single Particle Analysis vi DBT sponsored training program on Fermentation and Bioseparation Methods Dept. of Microbiology, Pondicherry University National 10-01-2015 10-01-2015 2015
3 Conformational Changes and Dynamics of Bioactive Peptides - Role of Biophysical Techniques and Compu National Conference on Bioactive Peptides – Application in Veterinary, Medical and Food Sciences Madras Veterinary College, Chennai – 7. National 18-12-2014 19-12-2014 2014
4 Applications of bio-nanotechnology as seen by structural biologist. National Conference on Nanotechnology’s Invisible Threat : Small Science, Big Consequences. Mahatma Gandhi National Institute of Research and Social Action, Hyderabad National 26-09-2013 27-09-2013 2013
5 Resource person at Refresher Course Refresher Course Academic Staff College, Pondicherry University National 26-09-2013 27-09-2013 2013
6 Bionanotechnology : Nanotechnology as seen by a Biologist. National seminar on Nano Science and Technology DRW College, Gudur – 524 101, AP National 02-03-2012 02-03-2012 2012
7 Electron Microscopy and single particle analysis – A promising combination in structural biology National Seminar on Computational Biology Centre for Bioinformatics, Ponsicherry University National 15-09-2010 17-09-2010 2010

Conferences/Seminars Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 National Seminar on Emerging Trends in Structural Biology & Bioinformatics Department of Biotechnology, New Delhi Centre for Bioinformatics, Pondicherry University; 3 days National 26-09-2012 28-09-2012 2012

Workshop Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year

Administrative Responsibilities in the Government and Quasi Government Agencies

S.No Name of the Position Agency/Organisation Duration Nature of Duties

Affiliation in Academic Bodies/Societies

S.No Name of the Body/Society Nature of Affiliation Year
1 The Indian Science Congress Association. Life Member 2010
2 Electron Microscope Society of India Life Member 2010

Participation & Extension Activities (Academic/Administraion)

S.No Name of the Position (Head, Dean, Co-ordinator, Director, etc.,) Duration Nature of Dutites

Participation & Extension Activities (Co-Curricular)

S.No Name of the Position (NSS, NCC, Warden etc.,) Duration Nature of Dutites

Collaboration with Institution/Industry

S.No Collaborator Name Designation Institution/Industry Type Nature of Collaboration Period of Collaboration Visits to Collaborating
Institution / Industry
Details of Collaborative Research/Teaching
From Date To Date From Date To Date

Faculty Development Programme Attended (Orientation, Refresher, other Short Term Course during the year)

S.No Title of the FDP Organiser Venue Duration From Date To Date Year

Details of Executive Development Prog/Management Development Prog. conducted

S.No Name of the Programme No. of Participants Venue Duration From Date To Date Year Revenue Generated

Participation in IMPESS, IMPRINT, SPARC, STARS, LEAP Programme etc and DSF Funding Programme

S.No IMPRESS/IMPRINT/SPARC/STARS/LEAP/Others Place From Date To Date Year

Enrolment under ARPIT Programme

S.No Name of the Programme Period of the Programme
From Date To Date