LAKSHMI P T V Professor

Profile Picture

  • Department of Bioinformatics
  • School of Life Sciences
  • lakshmiptv@yahoo.co.in

Academic Activity

Academic Activity Picture1

Academic Activity Picture2

Educational Qualification (UG,PG & Higher Order)

S.No Degree Subject/Title of thesis University/Board Year of Passing
1 Ph.D Botany University of Madras 2002
2 M.Phil Botany University of Madras 1997
3 M.Sc Botany University of Madras 1995
4 B.Sc Botany University of Madras 1993

Area of Specializaion

Awards / Prizes Conferred

S.No Name / Title of the Award Type Name of the Agency conferred the Award Year of the Award Amount for Cash Award
1 DST- Young Scientist award NATIONAL Department of Science & Technology, New Delhi 2010 -
2 Visiting Fellow INTERNATIONAL Institute of Plant and Microbial Biology, Academia Sinica 2006 -
3 Best orator NATIONAL Indian Botanical Society 2000 -

Teaching Experience

S.No Designation Department/Centre Institution
1 Professor Centre for Bioinformatics Pondicherry University
2 Associate Professor Centre for Bioinformatics Pondicherry University
3 Reader Centre for Bioinformatics Pondicherry University
4 Assistant professor Department of Bioinformatics Bharathiar University
5 Lecturer Department of Biotechnology Hindustan Arts and Science College, Padur, Chennai

Research Experience

S.No Designation Department/Centre Institution Area of Research
1 Assistant professor Bioinformatics Bharathiar University Phytomatics
2 Reader Centre for Bioinformatics Pondicherry University Phytomatics
3 Associate Professor Centre for Bioinformatics Pondicherry University Phytomatics
4 Professor Centre for Bioinformatics Pondicherry University Phytomatics
5 Research Associate CAS in Botany University of Madras Digital inventory of herbariums
6 Junior Consultant R & D Division Business Intelligence unit, Reliance Life Sciences Database on medicinal plants of India

Industry Experience

S.No Designation Company/Corporate Nature of Work
1 Junior Consultant Business Intelligence unit, Reliance Group of Life Sciences, Chennai. India Consultant

Contribution towards Innovation

S.No Name of the Work/Contribution Specialization Remarks

Patent Details

S.No Title Status Patent Number Year of Award Type Commercialized Status

Papers Published in UGC Approved Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 Multidisciplinary studies to evaluate the anti-quorum sensing ability of phyto-comounds in Ruellia patula Jacq Chemmugil. P, Lakshmi. P. T. V Avicenna Journal of Medical Biotechnology (AJMB) In press 2018 0.52
2 Secretome analysis of diarrhea-inducing strains of Escherichia coli Nirujogi. R. S, Muthusamy. B, Kim M. S, Sathe. G. J, Lakshmi. P. T. V, Kovbasnjuk. O. N, Prasad. T. S, Wade. M, and Jabbour. R. E Proteomics 17(6) 2017 4.041
3 A comprehensive look of poly(ADP-ribose) polymerase inhibition strategies and future directions for cancer therapy Chandan Kumar; Nidhi Rani, Lakshmi. P. T. V Future Medicinal Chemistry 9(1):37-60 2016 3.556
4 Allosteric site mediated active site inhibition of PBP2a using Querecetin 3-O-Rutinoside and its combination Nidhi Rani, Saravanan Vijayakumar, Lakshmi P.T.V and Annamalai Arunachalam Journal of Biomolecular Structure and Dynamics 34(8) 2016 2.92
5 Dualpred: A Webserver For Predicting Plant Proteins Dual-Targeted To Chloroplast And Mitochondria Using Split Protein Relatedness-Measure Feature Saravanan V, and Lakshmi. P. T. V Current Bioinformatics 10(3): i, 2015 2.017
6 In silico analysis of binding efficiency of quercetin with cancer targets Sathishkumar. R, Lakshmi. P. T. V, and Annamalai. A Advances in Biomedicine and Pharmacy 2(4): 169-174 2015 0.435
7 An insight in to the potentially old-wonder molecule-Quercetin: the perspective in foresee Rani. N, Lakshmi. P. T. V, Vijaykumar. S, Arunachalam. A Chinese Journal of Integrative Medicine xx 2015 1.401
8 Molecular Inhibition Of Telomerase Recruitment Using Designer Peptides: An In-Silico Approach Amit Jaiswal and Lakshmi P.T.V Journal of Biomolecular Structure & Dynamics 33(7):1442-59 2014 2.983
9 ACPP: A Web Server forPrediction and Design of Anti-cancer Peptides Saravanan Vijayakumar and Lakshmi P.T.V International Journal of Peptide Research and Therapeutics 21(1): 99–106 2014 1.28
10 Quercetin 3-O-rutinoside mediated inhibition ofPBP2a: computational and experimental evidence to its anti-MRSA activity Nidhi Rani, Saravanan Vijayakumar, Lakshmi P. T. V Molecular BioSystem 10(12):3229-37 2014 3.183
11 NF-κB activation and proinflammatory cytokines mediated protective effect of Indigofera caerulea Roxb. OnCCl4 induced liver damage in rats Guruvaiah Ponmari, Arunachalam Annamalai, Velliyur Kanniappan Gopalakrishnan, Lakshmi P. T. V International Immunopharmacology 23(2):672-80 2014 2.722
12 Inhibition of Pore Formation by Blocking the Assembly of Staphylococcus aureus α-Hemolysin Through a Novel Peptide Inhibitor: an In silco Approach Nidhi Rani, Saravanan. V, Lakshmi P. T. V International Journal of Peptide Research and Therapeutics 20(4): 575–583 2014 1.28
13 – A fuzzylogic based allergen predictor Saravanan. V, and Lakshmi P. T. V Omics : A Journal of Integrative Biology 18(9):570-81 2014 2.77
14 Green synthesis and characterization of Ag NPs using aqueous extract of Phyllanthus maderaspatensis L Annamalai. A, Christina. V. L. P, Christina. V, and Lakshmi P. T. V Journal of Experimental Nanoscience 9(2):113-119 2014 1.043
15 Sequence Analysis For Structure AndFunction Characterization Of Glutathione Reductase From Nostoc Sp. Ithayaraja.C. M and Lakshmi P. T. V International Journal of Universal Pharmacy and Bio Sciences 2(2): 9-47 2013 0.288
16 Green synthesis, characterization and antimicrobial activity of Au NPs using Euphorbia hirta L. leaf extract Annamalai. A, Christina. V. L. P, Sudha. D, Kalpana, Lakshmi P. T. V Colloids and Surfaces B: Biointerfaces 108: 60– 65 2013 4.287
17 SCLAP: An Adaptive Boosting Method for Predicting Sub- chloroplast Localization of Plant Proteins Saravanan. V, and Lakshmi P. T. V OMICS A Journal of Integrative Biology 17(2): 106-115 2013 2.730
18 APSLAP: An AdaptiveBoosting Technique for Predicting Subcellular Localization of Apoptosis Protein Vijayakumar Saravanan, and Lakshmi P. T. V Acta Biotheoretica 61:481–497 2013 0.950
19 Evaluation of phytochemical constituents and antioxidant activities of successive solvent extracts of leaves of Indigofera caerulea roxb using variou Ponmari Guruvaiaha, AnnamalaiArunachalam, and Lakshmi. P. T. V Asian Pacific Journal of Tropical Disease 2(1): S118-S123 2012 0.75
20 Plant Informatics- An Insight Lakshmi. P. T. V Pharmacognosy Communications 2(1):5-11 2012 0.432
21 Evaluation of phytochemical constituents and antioxidant activities of successive solvent extracts of leaves of Indigofera caerulea Roxb using various Ponmari .G, Annamalai. A, andLakshmi. P. T. V Asian Pacific Journal of Tropical Disease S118-S123 2012 0.75
22 Evaluation of Genetic Diversity in Cardiospermum halicacabum based on Geographical Variation Using RAPD Markers Annamalai.A, Christina. V.L, and Lakshmi. P. T. V Pharmacognosy Communications 2(1): 64-67 2012 0.75

Papers Published in Peer Reviewed Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 Exploring the Phyto-Constituents of Ruellia patula (Acanthaceae) as Antibacterial Agent 3. Chemmugil. P, Lakshmi. P. T. V and Annamalai. A EC Microbiology 7(5):133-148 2017 Refereed Journal
2 Methicillin Resistant Staphylococcus aureus and Antibiotic Resistance Lakshmi PTV EC Microbiology Opinion 6(1): 1 2017 Refereed Journal
3 Reduction of Silver Ions by Cell Free Extracts of Westiellopsis sp. Lakshmi. P. T. V, Devi Priyanka, and Annamalai. A International Journal of Biomaterials 2015(539494): 1-6 2015 Refereed Journal
4 Detection and ComparativeAnalysis of Uber-operons of FabZ gene Responsible for Fatty Acid Biosynthesis in Nostoc Punctiforme Cyanobacterium Lakshmi P.T.V, SathyaPriya, and Annamalai. A Research & Reviews: A Journal of Bioinformatics 1(1): 23-35 2014 Refereed Journal
5 Insilico Modelling and Comparative Docking Studies of EWS-FLI1 Responsible for Ewing Sarcoma in Human Beings Lakshmi P. T. V, Pragna Lakshmi. T, and Annamalai. A Research & Reviews: A Journal of Bioinformatics 1(1): 36-45 2014 Refereed Journal
6 The Arabidopsis Stress Responsive Gene Database, International Journal of Plant Genomics Borkotoky. S, Saravanan. V, Jaiswal. A, Das. B, Selvaraj. S, Murali. A and Lakshmi P. T. V International Journal of Plant Genomics 1:1-3 2013 Refereed Journal
7 Molecular modeling approach and RMSD calibration for superimposed 3D structure of DHFR from Pneumocystis jiroveci (PCP) Jayaprakash. C, Lakshmi P. T. V Pneumocystis jiroveci (PCP), American Journal of PharmTech Research 3(1): 1-15 2013 Refereed Journal
8 SLocP Tool Box-An Integrated Platform for Predicting Sub Cellular Localization of Proteins Saravanan. V, and Lakshmi. P. T. V Journal of Computational Intelligence in Bioinformatics 5(2): 133-140 2012 Refereed Journal
9 Comparative Computational Analysis of Cystic Fibrosis Transmembrane Conductance Regulator Protein to Treat Lung Infections Subhashini. R, and Lakshmi. P. T. V International Journal of Medical Engineering and Informatics 4(4):351-361 2012 Refereed Journal
10 , Study on the Docking Analysis of Homocitrate Synthase Responsible for Hydrogen Production in Nostoc Punctiforme ATCC29133 Lakshmi. P. T. V, Devi Priyanka, and Annamalai. A American Journal of Bioinformatics Research 2(6): 110-118 2012 Refereed Journal
11 Estimation of biomass contents and phytoconstituent analysis of Enicostemma littorale Blume Sathiskumar. R,Lakshmi. P. T. V and Annamalai. A Int. J. Pharma and Bio Sciences 3(3): B506-B522 2012 Refereed Journal
12 High-throughput virtual screening for novel DHFR inhibitors of P. Jiroveci from the zinc database Jayaprakash Chinnappan, and Lakshmi. P. T. V Int. J. Applied biology and pharmaceutical technology 3(4):425-438 2012 Refeered Journal

Papers Published in Conference Proceedings

S.No Title Name of the Authors as per the order in Paper Details of Conference Publication Page Nos. Year
1 A Fuzzy Inference System for Predicting Allergenicity and Allergic Cross-reactivity in Proteins Saravanan V and Lakshmi PTV IEEE International Conference Proceedings on Bioinformatics and Biomedicine. China - 2013

Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.
1 Pneumocystis jiroveci Pneumonia (BioInformatics approach) PTV Lakshmi, Jayaprakash C and Mohanraj LAP Lambert Academic Publishing 2014 978-3-8484-4559-2

Chapters in Books

S.No Title of the Chapters Name of the Authors Title of the Book Publisher Year ISBN No.

Edited Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Ongoing Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Ongoing Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Completed Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1  Insilico screening and comparision of Phyto-chemicals to target Angiotensinogen (AGT) of hypertension attributing to heart failure DST-Fast track 3 Rs. 14,61,200 2010
2  A Probablistic Approach to Interact the Substrate- Aloe emodin with proteins targeting for Neuroectodermal Tumor University Grants Commission, New Delhi 3 Rs. 9,66,800 2008

Completed Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Career Guidance Offered to students

S.No Name of the Scheme No. of Students Competitive Examinations/ Career Counseling No. of Students Passed No. of Students Placed

List of capability enhancement such as Soft skill development, Remedial coaching, Language lab,
Bridge courses, Yoga, Meditation, Personal Counselling and Mentoring etc.,

S.No Name of the Programme/Scheme Date of Implementation No. of Students Enrolled Agencies Involved

Research Guidance - PG

S.No Year Degree No. of Students Awarded Department/Centre
1 2011 M.PHIL 1 Bharathiyar University
2 2010 M.PHIL 2 Bharathiyar University
3 2009 M.PHIL 3 Bharathiyar University
4 2008 M.PHIL 4 Bharathiyar University
5 2007 M.PHIL 1 Bharathiyar University

Research Guidance - Ph.D

S.No Student Name Registration Date Registration No. Thesis Title Thesis Submitted Status Thesis Submitted Date Vivavoce Completed Status Date Awarded
1 P. Chemmugil 30-07-2012 - Phytochemical Composition, anti-bacterial and anti-quorum sensing potential of Ruellia patula Jacq. (Acanthaceae) NO NO
2 Raja Rajeswary T 16-09-2016 - Drought responsive gene regulation in Poaceae Family : Insilco approach NO NO
3 Ithayaraja, M 09-07-2011 - Studies on the Physiological Characterization and Theoretical Analysis of Glutathione Reductase in the Cyanobacterium- Nostoc Sp. YES 31-12-2013 YES 22-08-2014
4 Sathish Kumar 09-07-2007 - Studies on the effect of isolated and Characterized Phytochemical Compound of Enicostemma littorale Blume on the cancer targets YES 10-02-2011 YES 09-08-2011
5 Jeyaprakash, C 08-07-2009 - Exploiting High-Performance DHFR Interactions (in silico and in vitro) to target Pneumonia YES 28-09-2012 YES 09-12-2013
6 S. Subhasini 07-07-2008 - In silico and invitro evaluation of the anti-tumor property of Aloe emodin as a potential lead for primitive neuro ectodermal tumor YES 31-08-2011 YES 08-05-2012
7 Faizan Ahmad 06-06-2016 - Therapeutics for Anti- Angiogenesis in Non-small lung cancer – An In-Silico and In-vivo approach NO NO
8 Abhijeet Roy 06-06-2016 - Omics approaches to unravel the mechanism of host-pathogen interactions in fungal systems NO NO
9 Pa Rajalakshmi 05-07-2008 - In silico analysis of Phytochemicals isolated and characterized from Aloe vera L. as a Potential Drug for Cancer YES 31-08-2011 YES 09-04-2012
10 Nidhi Rani 05-06-2013 - Inhibitory effect of quercetin derivatives on penicillin binding protein (PBP2A) of Methicillin resistance Staphylococus aureus YES 30-04-2016 YES 27-03-2017
11 Saravanan V 04-07-2013 - Ensemble Machine Learning Approaches for Functional Annotation of Plant proteomes YES 29-08-2014 YES 06-03-2015
12 Chandan Kumar 03-09-2014 - Identification and Evaluation of Specific PARP-1 Inhibitors as a Potent Anticancer Agents NO NO
13 Aiswarya Jayaprakash 01-09-2016 - Unraveling the Host Pathogen Interaction Mechanism of Arachis hypogaea L. With Aspergillus flavus NO NO

Research Guidance - Post Doctoral

S.No Scholar Name Designation Funding Agency Fellowship Title Year of Joining Year of Completion

Financial assistance availed to attend conferences / workshops and to pay membership fee
of professional bodies during the year

S.No Conference/ workshop attended for which financial support provided Professional body for which membership fee is provided Amount of Support Place From Date To Date Year

E-Lecture Details

S.No E-Lecture Title Development of e-content/e-learning/delivering Member of Editorial Bodies Reviewer/Referee of
Content/Module Title Institution/Platform Year Weblink

Details of Online Education Conducted

S.No Nature of Online Course No. of Sessions Target Group Date

Invited Talks in Conference/Seminar/Workshop/Training Programme

S.No Title of the Paper Conferences/Seminar/Workshop/Training Programme Organized by Whether International / National / State / Regional / College or University Level From To Year
1 Methods and resources for pathway and gene network analysis Refresher Course HRDC, Pondicherry University National 10-12-2017 10-12-2017 2017
2 2. Exploiting In-Silico and Wet-lab based Approaches to Study the Therapeutic Potentials of phyto-co Seminar Sengamala Thayar Educational Trust Women’s College, Sundarakottai, Mannargudi, Thanjavur National 22-09-2017 22-09-2017 2017
3 3. Role of computers in biology in RUSA sponsored Workshop on Applications of Software tools in Plan workshop Bharathidasan Government College for Women, Pondicherry College 12-04-2017 12-04-2017 2017
4 4. A visit to the recent progress of cyanobacterial cells as the factory of biofuel Symposium Centre for Bioinformatics, Pondicherry University National 24-02-2017 24-02-2017 2017
5 5. The Journey of Bioinformatics for Microbial Studies Training programme Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University National 31-12-2016 31-12-2016 2016
6 7. Role of Bioinformatics databases and tools in the process of drug design Refresher Course HRDC, Pondicherry University National 03-03-2015 03-03-2015 2015
7 9. Medicinal Plant Informatics- use of databases, tools and insilico methods for drug design Conference Department of Botany, Quied-a-Milleth Govt College, Chennai National 09-01-2015 09-01-2015 2015
8 10. The prospective Approaches of Converting of OTUs to MOTUs using modern tools Refresher Course HRDC, Pondicherry University National 05-12-2013 05-12-2013 2013

Conferences/Seminars Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 Cross-talks in OMICS Pondicherry University and ICMR Pondicherry University 1 Day National 09-08-2017 09-08-2017 2017
2 Advances in Structural and Functional Bioinformatics (ASFB2008) Tamil Nadu State Council for Higher Education Bharathiar University National 12-08-2008 12-08-2008 2008

Workshop Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 Perspectives of Chemoinformatics for drug discovery DST Pondicherry University National 13-02-2013 16-02-2013 2013
2 Drug Design and Industrial Applications DBT Pondicherry University National 05-03-2012 08-03-2012 2012

Administrative Responsibilities in the Government and Quasi Government Agencies

S.No Name of the Position Agency/Organisation Duration Nature of Duties

Affiliation in Academic Bodies/Societies

S.No Name of the Body/Society Nature of Affiliation Year
1 Indian Science Congress Association Life member 2010
2 Indian Botanical Society Member 2000

Participation & Extension Activities (Academic/Administraion)

S.No Name of the Position (Head, Dean, Co-ordinator, Director, etc.,) Duration Nature of Dutites
1 Vice Chancellor nominee 3 years Academic and admission commitees of various departments
2 governing body 3 years Member of the governing body of Raak Nursing and Paramedical College and Manakula Vinayaka Institute of Technolgy, Puducherry
3 Inspection Committee 3 years Member of Inspection Committee for various programs of affiliated colleges
4 Stock verification committee member 3 years auditing of books, furnitures, softwares, hardwares, tools, chemicals and glasswares including instruments to various departments
5 Library committee 3 years Member of the Library committee
6 planning and purchase Member 3 years planning and purchase of books, equipments, chemicals etc for the Center. Selection committee for DBT trainee fellowship admission
7 Admission co-ordinator 10 years PG and Ph.D admissions
8 Advisory Board Committee member 10 years Advisory Board Committee for UGC –SAP –Centre for Bioinformatics
9 Faculty in charge 14 years formation of both PG and Ph. D Time table for course work and for the conduct of examinations

Participation & Extension Activities (Co-Curricular)

S.No Name of the Position (NSS, NCC, Warden etc.,) Duration Nature of Dutites

Collaboration with Institution/Industry

S.No Collaborator Name Designation Institution/Industry Type Nature of Collaboration Period of Collaboration Visits to Collaborating
Institution / Industry
Details of Collaborative Research/Teaching
From Date To Date From Date To Date

Faculty Development Programme Attended (Orientation, Refresher, other Short Term Course during the year)

S.No Title of the FDP Organiser Venue Duration From Date To Date Year

Details of Executive Development Prog/Management Development Prog. conducted

S.No Name of the Programme No. of Participants Venue Duration From Date To Date Year Revenue Generated

Participation in IMPESS, IMPRINT, SPARC, STARS, LEAP Programme etc and DSF Funding Programme

S.No IMPRESS/IMPRINT/SPARC/STARS/LEAP/Others Place From Date To Date Year

Enrolment under ARPIT Programme

S.No Name of the Programme Period of the Programme
From Date To Date