THIRUNAVVKKARASU.C Professor

Profile Picture

  • Department of Biochemistry & Molecular Biology
  • School of Life Sciences
  • tchinnasamy@hotmail.com,tarasu.bbm@pondiuni.edu.in

Academic Activity

Academic Activity Picture1

Academic Activity Picture2

Educational Qualification (UG,PG & Higher Order)

S.No Degree Subject/Title of thesis University/Board Year of Passing
1 Ph.D. Medical Biochemistry University of Madras 2001
2 M. Sc., Biochemistry Annamalai University 1996
3 B. Sc., Chemistry University of Madras 1993

Area of Specializaion

Liver diseases; Anti-cancer therapy through nanomedicine

Awards / Prizes Conferred

S.No Name / Title of the Award Type Name of the Agency conferred the Award Year of the Award Amount for Cash Award
1 Raman Post-Doctoral Fellowship in U.S.A- 2014" NATIONAL UGC, India. 2014 -
2 "Fellow” (FABMS) NATIONAL Indian Association of Biomedical Scientists. 2011 -
3 Young scientist travel award INTERNATIONAL American Society of Pharmacology and Experimental Therapeutics, 2005 -
4 Postdoctoral travel award INTERNATIONAL American Society of Biochemistry and Molecular Biology 2003 -
5 Best paper/poster presentation REGIONAL University of Pittsburgh, Pittsburgh, USA. 2002 -
6 Mrs. Indra Vasudevan Award, NATIONAL Indian Association of Biomedical Scientists 2000 -

Teaching Experience

S.No Designation Department/Centre Institution
1 Assistant Professor (Stage I) Biochemistry Periyar University, TN, India
2 Assistant Professor (Stage II) Biochemistry and Molecular Biology Pondicherry University, Puducherry, India
3 Assistant Professor (Stage III) Biochemistry and Molecular Biology Pondicherry University, Puducherry, India.
4 Associate Professor Biochemistry and Molecular Biology Pondicherry University, Puducherry, India
5 Professor Biochemistry and Molecular Biology Pondicherry Univeristy

Research Experience

S.No Designation Department/Centre Institution Area of Research
1 Visiting Research Associate Surgery; Thomas E Starzl Transplantation Institution University of Pittsburgh, USA Hepatplogy
2 Assistant Professor (Stage I) Biochemistry Periyar University, TN, India Hepatplogy
3 Assistant Professor (Stage II) Biochemistry and Molecular Biology Pondicherry University, Puducherry, India. Hepatplogy
4 Assistant Professor (Stage III) Biochemistry and Molecular Biology Pondicherry University, Puducherry, India. Hepatplogy
5 Visiting Scientist Department of Medicine - Gastroenterology and Liver diseases Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, USA Hepatology
6 Associate Professor Biochemistry and Molecular Biology Pondicherry University Hepatology
7 Professor Biochemistry and Molecular Biology Pondicherry Univeristy Hepatology

Industry Experience

S.No Designation Company/Corporate Nature of Work
1 NIL NIL NIL

Contribution towards Innovation

S.No Name of the Work/Contribution Specialization Remarks

Patent Details

S.No Title Status Patent Number Year of Award Type Commercialized Status

Papers Published in UGC Approved Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 The relevance of acid sphingomyelinase as a potential target for therapeutic intervention in hepatic disorders: Current scenario and anticipated trend Mir IH, Thirunavukkarasu C. Archives of Toxicology. 97, 8 & 2069-2087. 2023 6.1
2 Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non-alcoholic fatty liver disease. Shreyoshi Guha S, Sesili S, Mir IH, Thirunavukkarasu C. Cell Biochemistry and Function 44,1 & 4-19 2023 3.963
3 Selenium conditioning decreases antioxidant enzyme activity and delays germination potency of Macrotyloma uniflorum and Vigna radiate Nithyananthan S, Somenath S, Sreenadh B, Thirunavukkarasu C, Nasraddin OB, Mohammad S, Mohammad HA, Abubucker PM, Thiyagarajan R, Lokanatha V Journal of King Saud University - Science 35. 2 & 102501 2023 3.829
4 Biomimetic formation of silver oxide nanoparticles through Diospyros montana bark extract: Its application in dye degradation, antibacterial and antic Sujatha V, Kaviyasri G, Venkatesan A, Thirunavukkarasu C, Acharya S, Dayel SB, Al-Ghamdi S, Abdelzaher MH, Shahid M, Ramesh T Journal of King Saud University - Science 35, 3 & 102563 2023 3.829
5 Inhibition of glutathione generation in hepatic steatotic rats augment oxidative stress. Silja K, Selvaganabathy N, Kalaiselvi T, Thirunavukkarasu C Toxicology Mechanisms and Methods https://doi.org/10.1080/15376516.2023.2202784 2023 4.019
6 Selenium nanoparticles show anti-cancer activity through regulation of HIF-1α and HIF-2α under hypoxic condition in liver cancer cells Acharya S, Nithyananthan S and Thirunavukkarasu C. DNA and Cell Biology 42,7 & 433-444 2023 3.55
7 Multi-spectroscopic analysis decodes the interaction of vanadium nanoparticles with calf thymus DNA and its anticancer effect against hepatocellular c Guha S, Nancy K, Mir IH, Raghavendar C, Sujatha V, Mohanty AK, Kumar MS, Thirunavukkarasu C. Journal of Cluster Science. doi.org/10.1007/s10876-023-02452-5 2023 3.447
8 Elucidation of 7,8-dihydroxy flavone in complexing with the oxidative stress-inducing enzymes, its impact on radical quenching and DNA damage: An in s Mir IH, Aswathy SA, Guha S, Mohanty AK, Kumar MS, Sujatha V, Ramesh T, Thirunavukkarasu C. Journal of Biomolecular Structure & Dynamics. DOI: 10.1080/07391102.2023.2218932 2023 5.235
9 Transcriptional profiling reveals ataxia telangiectasia mutated pathways regulate joint copper and arsenic toxicity for hepatic metalloplasia and anti Thirunavukkarasu C, Sharma Y, Tchaikovskaya T, Maslov AY, and Gupta S. Life Sciences 305 & 120787 https://doi.org/10.1016/j.lfs.2022.120787 2022 6.78
10 A Mechanistic Review on Plant-derived Natural Inhibitors of Human Coronaviruses with Emphasis on SARS-COV-1 and SARS-COV-2. Guguloth SK, Lakshmi A R, Rajendran R, Rajaram K, Chinnasamy T, Huang JD, Zhang H, Senapati S, and Durairajan SSK. Curr Drug Targets. 23, 8 & 818-835 2022 2.937
11 The prominence of potential biomarkers in the diagnosis and management of hepatocellular carcinoma: Current scenario and future anticipation. Hassan Mir I, Jyothi KC, Thirunavukkarasu C. Journal of Cellular Biochemistry 123(10):1607-1623 2022 4.480
12 Prevalence and characteristics of microplastics present in the street dust collected from Chennai metropolitan city, India Patchaiyappan A, Dowarah K, Ahmed SZ, Prabakaran M, Jayakumar S, Thirunavukkarasu C, Devipriya SP Chemosphere 269, https://doi.org/10.1016/j.chemosphere.2020.128757 2021 7.086
13 Enhanced hepatocyte survival and anti-apoptosis via Akt by diallyl trisulfide, augments hepatic regeneration through hydrogen sulfide in partially hep Nithyananthan S, Shreyoshi Guha, Ishfaq Hassan Mir, and Thirunavukkarasu C Phytomedicine Plus 1(4); 2021, 100048; 2021 Elsevier
14 Ameliorative effect of alcoholic fatty liver in mice by the medicinal value-enhanced porridge made with Macrotyloma Uniflorum and Vigna Radiata. Nithyananthan S, Subhiksha S, Guha S, Ishfaq Hassan Mir, Jajnasenee Behera and Thirunavukkarasu C. Japanese Journal of Gastroenterology and Hepatology. V6(6); 1-12. 2021 1.920
15 Prevalence of microplastics in the sediments of Odisha beaches, southeastern coast of India Patchaiyappan A, ZakiAhmed S, Dowarah K, Khadanga SS, Singh T, Jayakumar S, Thirunavukkarasu C, Devipriya SP. Marine Pollution Bulletin. 167; Article No. 112265 2021 5.553
16 Targeting molecular signal transduction pathways in hepatocellular carcinoma and its implications for cancer therapy Hassan Mir I, Guha S, Behera J, Thirunavukkarasu C Cell Biology International 45 (11); 2161-2177 2021 4.473
17 Nutrient mixture from germinated legumes: Enhanced medicinal value with herbs-attenuated liver cirrhosis. Nithyananthan S, Keerthana P, Umadevi S, Guha S, Mir IH, Behera J, Thirunavukkarasu C. Journal of Food Biochemistry 44 (1), e13085 doi.org/10.1111/jfbc.13085 2020 2.720
18 Arsenic trioxide, a cancer chemo drug hamper fibrotic liver regeneration by interrupting oxidative stress rekindling and stellate cell rejuvenation. Nithyananthan S and Thirunavukkarasu C. Journal of Cellular Physiology 235, 1222-1234. 2020 6.384
19 Biosynthesis of graphene oxide based zinc oxide nanocomposite using Dalbergia latifolia leaf extract and its biological applications. Elavarasan N, Prakash S, Kokila K, Thirunavukkarasu C and Sujatha V. New Journal of Chemistry 44, 2166-2179. 2020 3.591
20 Isolation of hesperetin - A flavonoid from Cordia sebestena flower extract through antioxidant assay guided method and its antibacterial, anticancer e Prakash S, Elavarasan N, Subashini K, Kanaga S, Dhandapani R, Sivanandam M, Kumaradhas P, Thirunavukkarasu C and Sujatha V. Journal of Molecular Structure 1207; Article No. 127751. 2020 3.196
21 Curcuma longa and Trigonella foenum graecum enriched nutrient mixture from germinated Macrotyloma uniflorum and Vigna radiate ameliorate non-alcoholic Nithyananthan S, Sushmaa D, Myrthong I , Valluru L, Guha S, Mir IH, Behera J, Thirunavukkarasu C. Journal of Food Biochemistry 44 (4), e13159 doi.org/10.1111/jfbc.13159 2020 2.720
22 Quantification of microplastics using Nile Red in two bivalve species Perna viridis and Meretrix meretrix from three estuaries in Pondicherry, India a Dowarah K, Patchaiyappan A, Thirunavukkarasu C, Jayakumar S, Devipriya SP. Marine Pollution Bulletin 153, Article No. 110982 2020 5.553
23 Synthesis, spectral characterization and antitumor activity of phenothiazine derivatives. Venkatesan K, Satyanarayana VSV, Sivakumar A, Ramamurthy CH, Thirunavukkarasu C. Journal of Heterocyclic Chemistry 57,7 & 2722-2728 2020 2.193
24 Purification and characterization of non-enzymatic glycoprotein (NEGp) from flax seed buffer extract that exhibits anticoagulant and antiplatelet acti Sharath Kumar MN, Jayanna K, Chethana R, Chandramma, Ashwini S, Thirunavukkarasu, Rohith LS, Devaraja S. International Journal of Biological Macromolecules 163, 317–326. 2020 5.162
25 Flaxseed cysteine protease exhibits strong anticoagulant, antiplatelet, and clot dissolving properties. Nandish SKM, Kengaiah J, Ramachandraiah Ch, Chandramma, Shivaiah A, Santhosh SM, Thirunavukkarasu, and Sannaningaiah D. Biochemistry (Moscow) 85, 9 & 1113-1126 2020 3.162
26 Synthesis and characterization of novel bioactive azo compounds fused with benzothiazole and their versatile biological applications Prakash S, Somiya G, Elavarasan N, Subashini K, Kanaga S, Dhandapani R, Sivanandam M, Kumaradhas P, Thirunavukkarasu C and Sujatha V Journal of Molecular Structure. Article No. 129016, doi.org/10.1016/j.molstruc.2020.129016 2020 3.196
27 Chemotherapeutic doses of arsenic trioxide delays hepatic regeneration by oxidative stress and hepatocyte apoptosis in partial hepatectomy rat. Nithyananthan S and Thirunavukkarasu C Toxicology and Applied Pharmacology 382,114760. 2019 3.347
28 Phosphorylated abacavir analogue (ABC‐1) has ameliorative action against Newcastle Disease Virus (NDV) induced pathogenesis in chicken. Suresh KA, Venkata Subbaiah KC, Thirunavukkarasu C, Chennakesavulu S, Rachamallu A, Chamarti NR, Wudayagiri R and Valluru L. Biotechnology and Applied Biochemistry 66(6), 977-989 2019 2.431
29 Augmenter of liver regeneration enhances cell proliferation through the microRNA-26a/Akt/cyclin D1 pathway in hepatic cells. Gupta P, Sata TN, Ahamad N, Islam R, Yadav AK, Mishra A, Nithyananthan S, Thirunavukkarasu C, Sanal MG and Venugopal SK. Hepatology Research 49, 1341-1352. 2019 4.288
30 Synthesis and characterisation of arsenic nanoparticles and its interaction with DNA and cytotoxic potential on breast cancer cells. Subastri A, Arun V, Preeti Sharma, Preedia babu E, Suyavaran A, Nithyananthan S, Alshammari GM, Aristatile B, Dharuman V, Thirunavukkarasu C. Chemico-Biological Interactions 295 & 73-83 2018 5.192
31 Unveiling anticancer potential of glibenclamide: Its synergistic cytotoxicity with doxorubicin on cancer cells Nithyananthan S, Suyavaran A, Preedia babu E, Subastri A, Arun V, Suresh Kumar M, Aristatile B, Alshammari GM, Thirunavukkarasu C Journal of Pharmaceutical and Biomedical Analysis 154, (-) & 294-301 2018 3.935
32 Anticancer potential of ZnO nanoparticle-ferulic acid conjugate on Huh-7 and HepG2 cells and diethyl nitrosamine induced hepatocellular cancer on Wist Preedia Babu E, Subastri A , Suyavaran A, Nithyananthan S, Suresh Kumar M, Premkumar K, Bharathidasan R, and Thirunavukkarasu C Nanomedicine-Nanotechnology Biology and Medicine 14, (2) & 415-428 2018 6.458
33 Neutrophil extracellular traps in acrolein promoted hepatic ischemia reperfusion injury: therapeutic potential of NOX2 and p38MAPK inhibitors. Suyavaran A, Girish KS, Kemparaju K, and Thirunavukkarasu C. Journal of Cellular Physiology 233, (4) & 3244-3261 2018 6.384
34 Troxerutin with copper generates oxidative stress in cancer cells: its possible chemotherapeutic mechanism against hepatocellular carcinoma. Subastri A, Preedia Babu E, Suyavaran A, Nithyananthan S, Bharathidasan R, and Thirunavukkarasu C. Journal of Cellular Physiology 233, (3) & 1775-1790 2018 6.384
35 Preconditioning methods in the management of hepatic ischemia reperfusion- induced injury: update on molecular and future perspectives. Suyawaran A and Thirunavukkarasu C. Hepatology Research 47, (1) & 31-48 2017 4.288
36 Selenium nanoparticles synthesized in aqueous extract of Allium sativum perturbs the structural integrity of Calf thymus DNA through intercalation and Preedia Babua E, Lokeswara Rao P, Suyavarana A, Subastri A, Sujatha A and Thirunavukkarasu C. Materials Science & Engineering C. 74, (-) & 597-608 2017 7.328
37 Effect of troxerutin on 2-aminoanthracene and DNA interaction and its anti-mutagenic property. Subastri A, Harikrishna K, Sureshkumar M, Alshammari GM, Aristatile B and Thirunavukkarasu C. Biomedicine and Pharmacotherapy. 88, (-) & 325–334 2017 6.529
38 Size dependent uptake and hemolytic effect of zinc oxide nanoparticles on erythrocytes and biomedical potential of ZnO-ferulic acid conjugates. Preedia Babu E, Subastri A, Suyavaran A, Premkumar K, Sujatha V, Aristatile B, Alshammari GM, Dharuman V and Thirunavukkarasu C. Scientific Reports 7,(1) & 4203 2017 5.133
39 Soanum torvum Swartz. fruit attenuates cadmium-induced liver and kidney damage through modulation of oxidative stress and glycosylation. Ramamurthy CH, Subastri A, Suyawaran A, Subbaiah KCV, Valluru L, and Thirunavukkarasu C. Environmental Science and Pollution Research 23, (8) & 7919-7929 2016 4.223
40 Exploration of disulfiram dealings with calf thymus DNA using spectroscopic, electrochemical and molecular docking techniques. Subastri A, Durga A, Harikrishna K, Sureshkumar M, Jeevaratnam K, Girish KS and Thirunavukkarasu C. Journal of Luminescence 170, (-) & 255-261 2016 3.599
41 TNF–α inhibition by GSH subdues I/R injury in young and aged rat liver Suyavaran A, Ramamurthy Ch, Mareeswaran R, Subastri A, Lokeswara rao P and Thirunavukkarasu C. Inflammation Research 64, (1) & 71-81 2015 4.575
42 Synthesis and biological evaluation of isoindoloisoquinolinone, pyroloisoquinolinone and benzoquinazolinone derivatives as poly (ADP-ribose) polymeras 20. Suyavaran A, Ramamurthy CH, Mareeswaran R, Shanthi YV, Selvakumar J, Mangalaraj S, Suresh Kumar M, Ramanathan CR, Thirunavukkarasu C. Bioorganic & medicinal chemistry 23, (3) & 488-498 2015 3.641
43 Nutrient profile of porridge made from Eleusine coracana (L.) grains: effect of germination and fermentation. Subastri A, Ramamurthy CH, Suyavaran A, Mareeswaran R, Mandal P, Rellegadla S, Thirunavukkarasu C Journal of Food Science and Technology 52, (9) & 6024–6030 2015 2.701
44 Influence of age on the free-radical scavenging ability of CeO2 and Au/CeO2 nanoparticles. Anandkumar M, Ramamurthy CH, Thirunavukkarasu C and Suresh Babu K. Journal of Materials Science 50, (-) & 2522–2531 2015 4.220
45 Spectroscopic and molecular docking studies on the interaction of troxerutin with DNA. Subastri A, Ramamurthy CH, Suyavaran A, Mareeswaran R, Lokeswara Rao P, Harikrishna M, Suresh Kumar M, Sujatha V and Thirunavukkarasu C. International Journal of Biological Macromolecules 78, (-) & 122–129 2015 6.953
46 Newcastle disease virus (NDV) Induces protein oxidation and nitration in brain and liver of chicken: Ameliorative effect of vitamin E. Subbaiah KCV, Valluru L, Rajendra W, Ramamurthy CH, Thirunavukkarusu C and Subramanyam R. International Journal of Biochemistry & Cell Biology 64, (-) & 97–106 2015 3.673
47 Extracellularly synthesized ZnO nanoparticles interact with DNA and augment gamma radiation induced DNA damage through reactive oxygen species. Preedia Babu E, Subastri A, Suyavaran A, Lokeshwara rao P, Suresh Kumar M, Jeevaratnam K, and Thirunavukkarasu C. RSC Advances 5,(- ) & 62067–62077 2015 3.361
48 Probing the interaction of troxerutin with transfer RNA by spectroscopic and molecular modeling. Subastri A, Ramamurthy CH, Suyavaran A, Lokeswara Rao P, Preedia Babu E, Harikrishna M, Sureshkumar M and Thirunavukkarasu C. Journal of Photochemistry and Photobiology, B: Biology 153,(-) & 137-144 2015 6.252
49 Unconjugated bilirubin exerts proapoptotic effect on platelets via p38-MAPK activation. Naveen Kumar SK, Thushara RM, Sundaram SM, Hemshekhar M, Paul M, Thirunavukkarasu C, Basappa, Nagaraju G, Raghavan SC, Girish KS, Kemparaju K and Rangappa KS. Scientific Reports 13, (5) & 15045 2015 5.133
50 The extra cellular synthesis of gold and silver nanoparticles and their free radical scavenging and antibacterial properties Ramamurthy CH, Padma M, Daisy mariya samadanam I, Mareeswaran R, Suyavaran A, Suresh Kumar M, Premkumar K and Thirunavukkarasu C Colloids and Surfaces B-Biointerfaces 102, (-) & 808-815 2013 5.268
51 Crocin, a dietary colorant mitigates the cyclophosphamide induced organ toxicities by modulating antioxidant status and inflammatory cytokines Jnaneshwari S, Hemshekhar M, Santhosh MS, Sunitha K, Thushara R, Thirunavukkarasu C, Kemparaju K and Girish KS. Journal of Pharmacy and Pharmacology 65, (4) & 604-614 2013 3.765
52 Inhibition of hyaluronidase by N-acetyl cysteine and glutathione: Role of thiol group in hyaluronan protection. Sunitha K, Suresh P, Santhosh MS, Hemshekhar M, Thushara RM, Marathe KG, Thirunavukkarasu C, Kemparaju K, Kumar MS, Girish KS. International Journal of Biological Macromolecule 55, (-) & 39-46 2013 6.953
53 Green synthesis and characterization of selenium nanoparticles and its augmented cytotoxicity with doxorubicin on cancer cells Ramamurthy CH, Sampath KS, Arunkumar P, Suresh Kumar M, Sujatha V, Premkumar K and Thirunavukkarasu C. Bioprocess and Biosystems Engineering 36, (8) & 1131-1139 2013 3.210
54 (-)- Epigallocatechin-gallate (EGCG) stabilize the mitochondrial enzymes and inhibits the apoptosis in cigarette smoke-induced myocardial dysfunction Gokulakrishnan A, Mani VM, Liyakath Ali A and Thirunavukkarasu C. Molecular Biology Reports 40, (12) & 6533-6545 2013 2.316
55 Polyphenol contents and antioxidant activity of Brassica nigra leaf extract Rajamurugan R, Selvaganabathy N, Kumaravel S, Ramamurthy CH, Sujatha V and Thirunavukkarasu C Natural Product Research 26, (23) & 2208-2210 2012 2.861
56 Evaluation of antioxidant, radical scavenging activity and polyphenolics profile in Solanum torvum L. fruits. Ramamurthy CH, Suresh Kumar M, Sujatha V, Suyavaran A, Mareeswaran R and Thirunavukkarasu C. Journal of Food Science 77, (8) & C907-C913 2012 3.167
57 Brassica nigra – plays a remedy role in hepatic and renal damage. Rajamurugan R, Suyavaran A, Selvaganabathy N, Ramamurthy CH, Pramodh Reddy G, Sujatha V and Thirunavukkarasu C. Pharmaceutical Biology. 50, (12) & 1488–1497. 2012 3.503
58 Lactobacillus plantarum AS1 isolated from south Indian fermented food Kallappam suppress 1, 2-Dimethyl hydrazine (DMH) induced colorectal cancer in ma Satish Kumar R, Kanmani P, Yuvaraj N, Paari KA, Pattukumar V, Thirunavukkarasu C, and Arul V. Applied Biochemistry and Biotechnology 166, (3) & 620 -631 2012 2.926

Papers Published in Non UGC Approved Peer Reviewed Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 The investigation of the efficacy of the prodrug DDI-10 against Newcastle disease virus infection in young chicken Suresh KA, Rayapu L, Subramanyam D, Rani Prameela D, Naga Raju C, Thirunavukkarasu C, Valluru L. Microbes Infect. Chemother. e1333. doi.org/10.54034/mic. e1333 2022 -
2 Potential of fruit peel waste in growing Cyanobacteria Anabaena cylindrica. Tan Yeong Hwang, Ho An Qi, Chai Mee Kin, Wong Ling Shing, Djearamane Sinouvassane, Thirunavukkarasu C. International Journal of Technology. 12 (4); 711-719 2021 p-ISSN: 2086-9614; e-ISSN: 2087-2100
3 Non-alcoholic fatty liver disease – A brief insight into pathogenesis and review of recent reports on therapeutic targets. Suyavaran A, Mareeswaran R, Ramamurthy C, Subastri A, Rao PL, Babu P, Thirunavukkarasu C. Journal of Liver and Clinical Research 2, (2) & 1014 2015 -
4 Evaluation of eco-friendly coagulant from Trigonella foenum-graecum seed. Ramamurthy CH, Uma Maheswari M, Selvaganabathy N, Suresh Kumar M, Sujatha V and Thirunavukkarasu C. Advances in Biological Chemistry 2, (-)& 58-63. 2012 -

Papers Published in Conference Proceedings

S.No Title Name of the Authors as per the order in Paper Details of Conference Publication Page Nos. Year
1 Inhibition of NADPH oxidase-2 and P38 mitogen activated protein kinase suppresses acrolein aggravated hepatic ischemia reperfusion injury through neut Suyavaran A and Thirunavukkarasu C. Journal of Hepatology 66 (1); S201-S2 2017
2 Arsenic (As) and copper (Cu) serve as cofactors to produce hepatotoxicity with mitochondrial damage, double strand DNA breaks and disruption of ATM si Thirunavukkarasu C, Sharma Y, Gupta P and Gupta S FASEB J 30 (1); 1026. 2016
3 Novel vasodilator and anti-inflammatory drug-based strategy for restoring ischemia/ reperfusion-exposed donor liver to healthy state. Thirunavukkarasu C, Jaber FL, and Gupta S. Hepatology 62 (1); 383A. 2015

Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Chapters in Books

S.No Title of the Chapters Name of the Authors Title of the Book Publisher Year ISBN No.

Edited Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Ongoing Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Treatment of Fatty Liver Diseases: Preclinical Investigation of a New Nutraceutical Multitarget Formulation DHR 2021-2024 33.9905 2021

Ongoing Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Completed Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 To enhance the therapeutic efficacy of doxorubicin by targeting hypoxia inducible factor 1α and 2α through selenium nano particles in hepatocellular carcinoma cells DST-SERB 2016-2018 10.58 2018
2 To investigate the effect of nitric oxide-releasing nonsteroidal anti-inflammatory compound in hepatocytes injury in steatosis DST-SERC 2012-2015 19.96 2015
3 Role of mitochondrial glutathione in the survival of young and aged primary rat hepatocytes ICMR-India 2011-2014 22.995 2014
4 Structure based drug design for Protein disulphide isomerase DBT-India (Co-PI) 2011-2014 44.764 2014
5 To investigate the glutathione level discrimination between oxidative stress and transforming necrosis factor-α signaling in the progression from hepatic steatosis to steatohepatitis UGC-India 2010-2013 10.492 2013
6 Effect of chromium VI on insulin resistance hepatocytes Pondicherry University-India 2009-2011 4.96 2011
7 Structure based drug design for Acidic Sphingomyelinase UGC-India (Co-PI) 2010-2013 10.45 2010

Completed Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Career Guidance Offered to students

S.No Name of the Scheme No. of Students Competitive Examinations/ Career Counseling No. of Students Passed No. of Students Placed

List of capability enhancement such as Soft skill development, Remedial coaching, Language lab,
Bridge courses, Yoga, Meditation, Personal Counselling and Mentoring etc.,

S.No Name of the Programme/Scheme Date of Implementation No. of Students Enrolled Agencies Involved

Research Guidance - PG

S.No Year Degree No. of Students Awarded Department/Centre
1 2021 M.SC 3 Biochemistry and Molecular Biology
2 2020 M.SC 3 Biochemistry and Molecular Biology
3 2019 M.SC 4 Biochemistry and Molecular Biology
4 2018 M.SC 2 Biochemistry and Molecular Biology
5 2017 M.SC 1 Biochemistry and Molecular Biology
6 2016 M.SC 2 Biochemistry and Molecular Biology
7 2015 M.SC 1 Biochemistry and Molecular Biology
8 2014 M.SC 2 Biochemistry and Molecular Biology
9 2013 M.SC 5 Biochemistry and Molecular Biology
10 2012 M.SC 4 Biochemistry and Molecular Biology

Research Guidance - Ph.D

S.No Student Name Registration Date Registration No. Thesis Title Thesis Submitted Status Thesis Submitted Date Vivavoce Completed Status Date Awarded
1 NITHYANANTHAN.S 24-08-2016 1600102002 Biochemical and molecular studies on the effect of chemotherapeutic dose of arsenic trioxide on hepatic regeneration in rats YES 08-07-2020 YES 29-04-2021
2 A. Subastri 10-08-2012 PU/CE/E9/PHD/2012-13 Binding insight of bioflavonoid troxerutin with nucleic acids and its anti cancer potential on hepatocellular carcinoma YES 06-07-2017 YES 28-03-2018
3 Preedia Babu 05-09-2013 PU/CE/E9/PHD/2013-14/1464 Ferulic acid assisted synthesis and characterization of ZnO nanoparticles and anticancer potential of ZnONPs-ferulic acid conjugates on hepatocellular carcinoma: An in vitro and in vivo study. YES 04-09-2017 YES 26-03-2018
4 A. Suyavaran 08-09-2011 PU/CE/E9/PHD/2011-2012 Pretreatment strategies for the suppression of hepatic ischemia reperfusion injury: Insights into molecular mechanisms of hepatic recovery. YES 03-02-2017 YES 15-11-2017
5 Ch. Ramamurthy 27-08-2009 PU/CE/E9/PHD/2010-2011 Antioxidant and antimutagenic effect of Solanum torvum fruit aqueous extract and its biogenic synthesis of nanoparticles for biomedical applications. YES 17-09-2014 YES 15-07-2015

Research Guidance - Post Doctoral

S.No Scholar Name Designation Funding Agency Fellowship Title Year of Joining Year of Completion
1 Dr. R. Rajkumar INSA Visiting Scientist INSA INSA Visiting Scientist 28-06-2022 27-07-2022
2 Dr. K. R. Jayappriyan Young Scientist Fellowship Tamil Nadu Science and Technology YSFS 04-05-2023 02-07-2023
3 Dr. Parthasarathy Rangarajan NPDF SERB National Post-Doctoral Fellowship 01-05-2018 01-11-2019

Financial assistance availed to attend conferences / workshops and to pay membership fee
of professional bodies during the year

S.No Conference/ workshop attended for which financial support provided Professional body for which membership fee is provided Amount of Support Place From Date To Date Year

E-Lecture Details

S.No E-Lecture Title Development of e-content/e-learning/delivering Member of Editorial Bodies Reviewer/Referee of
Content/Module Title Institution/Platform Year Weblink

Details of Online Education Conducted

S.No Nature of Online Course No. of Sessions Target Group Date

Invited Talks in Conference/Seminar/Workshop/Training Programme

S.No Title of the Paper Conferences/Seminar/Workshop/Training Programme Organized by Whether International / National / State / Regional / College or University Level From To Year
1 Review of Literature and Plagiarism National Level Online Seminar on Scientific Skills in Biological Research Organized by PG & Research Department of Biochemistry, St. Joseph's College of Arts and Science (Aut National 28-09-2021 29-09-2021 2021
2 Structure Based and Computer Aided Drug Design National Seminar on Recent Developments in Bio-Organic Chemistry (RDBOC-2020) PG & Research Department of Chemistry, Govt. Arts College, C. Mutlur, Chidambaram, TN, India National 03-03-2020 03-03-2020 2020
3 Functional food in cancer prevention National conference on Frontiers in Cancer Research FCR-2020 Department of Biochemistry, Arcot Sri Mahalakshimi Womens College, Villapakkam 632 521, Ranipet Dist National 05-02-2020 05-02-2020 2020
4 How bad cancer stem cells Applications of Molecular Biology Techniques and Computational Approaches in Disease Diagnosis, Prevention and Therapy Department of Biochemistry, Governments Arts College, Paramakudi, Affiliated to Alagappa University, National 20-12-2019 21-12-2019 2019
5 Nuclear Physics - A Blessing or Curse to Cancer Patients. Conference Department of Physics & Zoology, Vellalar College for Women, Affiliated to Bharathiar University, E National 07-08-2019 07-08-2019 2019
6 Bioflavonoid such as troxerutin on hepatocellular carcinoma National Seminar Series. Department of Studies & Research in Biochemistry, Tumkur University, Tumkur. KA, India. Regional 21-11-2017 21-11-2017 2017
7 Targeting appropriate cells in cancer: Cancer stem cells. Recent advances in biotechnology Department of biotechnology, Dravidian University, Kuppam, AP-517 426 National 09-02-2017 10-02-2017 2017
8 Cancer stem cells: How can we target them through biomarkers National seminar on “Biomarkers: From research to clinical practice Meenakshi College for women, Chennai-24, TN, India National 30-01-2017 31-01-2017 2017
9 Functional food in cancer prevention Current scenario and emerging trends in functional foods and neutraceutical chemistry Duvvuru Ramanamma Women College, Gudur, AP-524 101, India National 29-12-2016 29-12-2016 2016
10 Metastasis and angiogenesis in cancer National Seminar on Recent Trends in Life Sciences 2014” Department of Zoology, T.R.R. Government Degree College, Kandukur, AP-523 105, India National 07-08-2014 08-08-2014 2014
11 Nutritional management in cancer patient. National conference on Advances in the management and prevention of clinical disorders due to malnutrition Department of Biochemistry, Rajah Serfoji, Government College (Autonomous), Thanjavur-613 005, TN, I National 07-02-2013 08-02-2013 2013
12 Constitutive Release of Antioxidant-Scavenging molecule(s) by Hepatic Stellate Cells: Hepatic stella Recent Conference on Recent Discoveries in Protein Sciences Karnataka state higher education council and Tumkur University, Bangaluru, National 31-01-2013 31-01-2013 2013
13 Hepatic stellate cell as a target for liver diseases. One day national conference on “Molecular Diagnosis” Department of Studies & Research in Biochemistry, Tumkur University, Tumkur. National 13-07-2012 13-07-2012 2012
14 Free radical: Special reference to hepatic stellate cell activation in liver cirrhosis. National seminar on “Emerging trends in biotechnology: Challenges and opportunities” Department of biotechnology, Dravidian University, Kuppam, A.P-517 426 National 13-03-2012 15-03-2012 2012

Conferences/Seminars Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 1) 3rd National Conference on Drug Discovery and Development. DST, ICMR Pondicherry University, Pudcherry, India. 6th-7th March 2020 National 06-03-2020 07-03-2020 2020
2 Trends in Biochemistry in Post-Genomic Era (Organizing Committee Member) DST, ICMR and Pondicherry University Pondicherry University National 27-02-2018 28-02-2018 2018
3 Science day - Seminar (Organizing Chairmen) DST, and Pondicherry University Pondicherry University National 24-02-2017 24-02-2017 2017
4 Drug Discovery and Cancer Therapy (Organizing Committee Member) DST, and Pondicherry University Pondicherry University National 25-02-2016 26-02-2016 2016
5 Recent Trends in Biochemistry and Molecular Biology (Organizing secretary) Pondicherry University Pondicherry University National 17-03-2014 17-03-2014 2014
6 Drug discovery and cellular dynamics (One of the organizing member) DBT, Pondicherry University Pondicherry University National 21-03-2013 23-03-2013 2013
7 Current Scenario and Emerging Trends in Hepatocellular Diseases (Organizing Secretary) DST, ICMR and Pondicherry University Pondicherry University National 05-10-2012 06-10-2012 2012

Workshop Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year

Administrative Responsibilities in the Government and Quasi Government Agencies

S.No Name of the Position Agency/Organisation Duration Nature of Duties

Affiliation in Academic Bodies/Societies

S.No Name of the Body/Society Nature of Affiliation Year
1 Institute of Food Science, USA Annual Member 2012
2 The Indian Science Congress Association Life Member 2008
3 The Biotech Research Society [BRSI], India Life Member 2008
4 Indian Association for cancer Research Life Member 2006
5 Indian Association of Biomedical Scientists Life Member 2005
6 American Society for Pharmacology and Experimental Therapeutics Annual Member 2004
7 American Society for Biochemistry and Molecular Biology Annual Member 2002

Participation & Extension Activities (Academic/Administraion)

S.No Name of the Position (Head, Dean, Co-ordinator, Director, etc.,) Duration Nature of Dutites
1 Head (i/c) 24-01-2017 – 31-08-217 Department of Biochemistry and Molecular Biology, Pondicherry University
2 Co-ordinator 19-05-2016 to till date Central Animal House Facility, Pondicherry University
3 Co-Ordinator 27-09-2016 to 26-09-2020 PG Basic Clinical Sciences program of the School of Medical Sciences
4 Animal house in-Charge 22/01/2014 – 28/01/2015 Animal house, Pondicherry University

Participation & Extension Activities (Co-Curricular)

S.No Name of the Position (NSS, NCC, Warden etc.,) Duration Nature of Dutites
1 Deputy Warden 15-09-2009 TO 28-01-2015 Boys Hostel
2 Warden 17-07-2019 to Till date Boys Hostel

Collaboration with Institution/Industry

S.No Collaborator Name Designation Institution/Industry Type Nature of Collaboration Period of Collaboration Visits to Collaborating
Institution / Industry
Details of Collaborative Research/Teaching
From Date To Date From Date To Date

Faculty Development Programme Attended (Orientation, Refresher, other Short Term Course during the year)

S.No Title of the FDP Organiser Venue Duration From Date To Date Year

Details of Executive Development Prog/Management Development Prog. conducted

S.No Name of the Programme No. of Participants Venue Duration From Date To Date Year Revenue Generated

Participation in IMPESS, IMPRINT, SPARC, STARS, LEAP Programme etc and DSF Funding Programme

S.No IMPRESS/IMPRINT/SPARC/STARS/LEAP/Others Place From Date To Date Year

Enrolment under ARPIT Programme

S.No Name of the Programme Period of the Programme
From Date To Date