RUKKUMANI R. Professor

Profile Picture

  • Department of Biochemistry & Molecular Biology
  • School of Life Sciences
  • ruks2k2@yahoo.co.in, ruks2k2@gmail.com

Academic Activity

Academic Activity Picture1

Academic Activity Picture2

Educational Qualification (UG,PG & Higher Order)

S.No Degree Subject/Title of thesis University/Board Year of Passing
1 Ph.D Biochemistry Annamalai University 2005
2 M.Phil Biochemistry Annamalai University 2001
3 M.Sc., Biochemistry University of Madras 2000
4 B.Sc Biochemistry University of Madras 1998

Area of Specializaion

Molecular Medicine , Cancer Biology - Nano oncology, Targeted Therapy , Liver Toxicity , Phytotherapy

Awards / Prizes Conferred

S.No Name / Title of the Award Type Name of the Agency conferred the Award Year of the Award Amount for Cash Award
1 Bharat Siksha Gaurav Puraskar NATIONAL KTK Outstanding Achievers and Educational foundation 2021 -
2 GRABS Best Scientist Award NATIONAL Grabs Trust 2020 -
3 Best Research Award INTERNATIONAL International Research Awards on New Science Inventions 2020 -
4 Women achiever of the year 2019 REGIONAL Pondicherry University 2019 -
5 Magalir osai Women achiever award REGIONAL Maglir Osai Tamil Magazine 2019 -
6 Best Teacher 2018-19 REGIONAL Pondicherry University 2019 -
7 Renato Dulbecco Memorial Award for Best Speech INTERNATIONAL II World Cancer Congress 2018 -
8 Outstanding Woman - VIWA 2018 INTERNATIONAL Centre for Advanced Research and Design, Venus International foundation 2018 -
9 Best Teacher 2017-18 REGIONAL Pondicherry University 2018 -
10 Women Scientist award NATIONAL Biotechnology Research Society of India 2018 25000
11 Scientific excellence - Senior, Biozone Icon Awards 2018 NATIONAL Biozone Research Technologies 2018 -
12 Best Teacher 2013-14 REGIONAL Pondicherry University 2014 -
13 Best project award REGIONAL Scientific solutions 2014 -
14 Best Teacher 2011-12 REGIONAL Pondicherry University 2012 -
15 Best Paper presentation NATIONAL Annamalai University, Department of Biochemistry (UGC National Conference on Natural Products in Health) 2005 -
16 SRI BALAJI Endowment Research Gold Medal INTERNATIONAL Banaras Hindu University (International symposium of ISAR) 2003 -

Teaching Experience

S.No Designation Department/Centre Institution
1 Lecturer Systems Biology Hyderabad Central University
2 Assistant Professor Biochemistry & Molecular Biology Pondicherry University
3 Assistant Professor (on EOL) Biotechnology Madras University
4 Associate Professor Biochemistry & Molecular Biology Pondicherry University

Research Experience

S.No Designation Department/Centre Institution Area of Research
1 DBT - Post Doctoral Fellow Gene Therapy CCMB, Hyderabad Design of Gene Delivery Agent
2 Research Scientist Centre for Micronutrient Research,(Sponsored by Johns Hopkins University, Bloomberg School of Public Annamalai Univesrsity Evaluating innovative zinc supplementation Strategy, Effect of zinc given as treatment during diarrhea, zinc status on diarrhoeal and respiratory morbidity and growth in preschool children

Industry Experience

S.No Designation Company/Corporate Nature of Work
1 Publication Writer Novartis Pharmaceuticals Cardiovascular Medicine Division

Contribution towards Innovation

S.No Name of the Work/Contribution Specialization Remarks

Patent Details

S.No Title Status Patent Number Year of Award Type Commercialized Status
1 An Anticancer Compound from Sesbania Grandiflora and A Process Thereof APPLIED 201841033243 A 2018 NATIONAL NO

Papers Published in UGC Approved Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1  A novel anticancer chromeno-pyrimidine analogue inhibits epithelial-mesenchymal transition in lung adenocarcinoma cells.  Venkateswarareddy N, Sankar P, Srividya S, Suhail AB, Parthasarathi D, Savitha B, Syed Ali Padusha M & Rukkumani R*. Toxicology Mechanisms and Methods 31(6):401-412. 2021 2.987
2 Epigenetic modulation and apoptotic induction by a novel imidazo-benzamide derivative in human lung adenocarcinoma cells. Amrutha Arjunan, Sankar Pajaniradje, Arul Prakash Francis, Srividya Subramanian, Sathyapriya Chandramohan, D. Parthasarathi, Ayyiliath M. Sajith, M. Syed Ali Padusha,P. P. Mathur,Rukkumani Rajagopalan Daru J Pharm Sci. doi: 10.1007/s40199-021-00419-3. 2021 3.117
3 Indole curcumin combats metastatic HBV positive hepatocellular carcinoma by inhibiting cell proliferation, migration, and MMP-9 activity. Srividya S, Sankar P, Roshan T, Hoda M, Asmita D, Rukkumani R*. Journal of Cancer Research and Therapeutics In Press 2021 1.805
4 Role of Indole curcumin in the Epigenetic activation of Apoptosis and Cell cycle regulating genes Sathyapriya C,Oishi C,Sankar P, Srividya S, Suhail AB,Rukkumani R*. Journal of Cancer Research and Therapeutics In Press 2021 1.805
5 Synthetic curcumin analog: inhibiting the invasion, angiogenesis, and metastasis in human laryngeal carcinoma cells via NF‑kB pathway. Kumaravel Mohankumar, Arul Prakash Francis, Sankar Pajaniradje, Rukkumani R*. Molecular Biology Reports 48(8):6065-6074. 2021 2.316
6 Enhanced drug retention, sustained release, and anti-cancer potential of curcumin and indole-curcumin analog- loaded polysorbate 80-stabilizied PLGA n Sufi SA, Hoda M, Pajaniradje S, Mukherjee V, Coumar SM, Rajagopalan R. Int J Pharm 7;588:119738 2020 5.875
7 Indole Curcumin Reverses Multidrug Resistance by Reducing the Expression of ABCB1 and COX2 in Induced Multidrug Resistant Human Lung Cancer Cells. Sankar P, Kumaravel M, Rakesh R, Sufi SA, Srividya S, Parthiban A, Rao HSP, Rukkumani R*. Letters in Drug Design & Discovery 17(9): 1146 – 1154. 2020 1.150
8 Redox nano–architectures: Perspectives and Implications in Diagnosis and Treatment of Human Diseases Sufi SA, Pajaniradje S, Mukherjee V, Rukkumani R* Antioxidant Redox Signalling 30(5):762-785. 2018 8.401
9 Antioxidants: Friend or foe? Sarangarajan R, Meera S, Rukkumani R, Sankar P, Anuradha G Asian Pacific Journal of Tropical Medicine 10: 1111–1116 2017 1.910
10 Disulfiram and disulfiram-loaded poly-[lactide-co-glycolic acid] nanoparticles modulate metastatic markers and proteasomal activity in hepatocarcinoma Hoda M, Bindumadhuri C, Iqbal S, Garima S, Rukkumani R* Eur. J. Nanomed 9(3-4): 127-138 2017 0.85
11 Inhibition of metastasis and angiogenesis in Hep-2 cells by wheatgrass extract- an in vitro and in silico approach. Garima S, Sangeetha B, Hoda M, Rukkumani R* Toxicology Mechanisms and Methods 211-14 2017 2.987
12 Stabilizers Influence Drug-Polymer Interactions and Physiochemical properties of Disulfiram-Loaded PLGA Nanoparticles Hoda M, Sufi SA, Bindumadhuri C, Rukkumani R* Future Science OA 4:1-16 2017 3.250
13 In-silico and in-vitro anti-cancer potential of a curcumin analogue (1E, 6E)-1, 7-di (1H-indol-3-yl) hepta-1, 6-diene-3, 5-dione. Shamim AS, Lakshmi Narayana A , Safiulla Basha S, Victor M , Mohane S. Coumar, Surya Prakash Rao H, Rukkumani R* Biomedicine & Pharmacotherapy 85:389-398 2017 6.529
14 Anti-proliferative and apoptosis-triggering potential of disulfiram and disulfiram-loaded polysorbate 80-stabilized PLGA nanoparticles on hepatocellul Hoda M, Pajaniradje S, Shakya G, Mohankumar K, Rukkumani R* Nanomedicine: Nanotechnology, Biology, and Medicine 12, 1641-1650 2016 7.2
15 Hypoglycaemic role of wheatgrass and its effect on carbohydrate metabolic enzymes in type II diabetic rats. Garima S, Praveen Kumar R, Sankar P, Kumaravel M, Rukkumani R* Toxicol Indust Health 32(6):1026-1032 2016 2.273
16 miRNA-24 and miRNA-466i-5p controls inflammation in rat hepatocytes Hairul islam VI, Saravanan S, Thirugnanasambantham K, Haneith H, Karikalan K, Durairaj S, Rukkumani R Nature -Cell. Mol. Immunol 12: 113–115 2015 11.530
17 Influence of stabilizers on the production of disulfiram-loaded poly(lactic-co-glycolic acid) nanoparticles and their anticancer potential. Hoda M, Sufi SA, Shakya G, Kumar KM, Rukkumani R* Ther Deliv 6 (1), 17-25 2015 2.120
18 RP-HPLC analysis and oxidative stress mediated cytotoxic effect of methanol extract of wheatgrass by modulating NrF2 level in Hep-2 cells Garima S, Varalakshmi D, Muddasarul H, & Rukkumani R* International Journal of Pharma Science 5:897-903 2015 1.04
19 Methanol extract of wheatgrass induces G1 cell cycle arrest in a p53-dependent manner and down regulates the expression of cyclin D1 in Hep-2 cells Garima S, Sangeetha B, & Rukkumani R* Pharmacognosy Magazine 11:S139-S147 2015 1.525
20 BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway—A comparative st Kumaravel M, Subhashree S, Sankar P, Singh VK, Larance R, Banerjea A C, Dinesh B, Mohane Coumar S, Latha P & Rukkumani R* Biomedicine & Pharmacotherapy 74:178-186 2015 6.529
21 Design, synthesis, in vitro and in silico anti-cancer activity of 4H-chromenes with C4-active methine groups Parthiban A, Kumaravel M, Muthukumaran J, Rukkumani R, Krishna R, Surya Prakash Rao H Med Chem Res 24,(3) 1226–1240 2015 1.965
22 Hepatoprotective role of kaempferol during alcohol and ∆PUFA induced oxidative stress. Garima S, Selva M, Muddasar H, and Rukkumani R* J Basic Clin. Physiol. Pharmacol. 25:73-79 2014 1.69
23 Antihyperlipidemic effect of wheatgrass on alcohol and ∆PUFA induced liver toxicity in male albino wistar rats Varalakshmi D, Garima S, and Rukkumani R Int. J. pharm. pharmaceutic. sci 6:547-551 2014 1.59
24 Phytochemical screening and analysis of antioxidant properties of aqueous extract of wheatgrass Varalakshmi D, Garima S, Rukkumani R* Asia Pac J Trop Med S898-S904 2014 1.94
25 GC-MS Analysis, In Vitro Antioxidant and Cytotoxic Studies of Wheatgrass Extract Garima S, Sankar P, Hoda M, Varalakshmi D, Rukkumani R* American J Phytomed Clin Ther. 2: 877-893 2014 1.15
26 Apoptosis induction by an analog of curcumin (BDMC-A) in human laryngeal carcinoma cells through intrinsic and extrinsic pathways Kumaravel M, Sankar P, Subhashree S, Singh VK, Larance R, Banerjea A C, Benson C S, Mohane Coumar S, Latha P , Rukkumani R* Cellular Oncology 37:439–454 2014 6.730
27 Effect of wheatgrass on membrane fatty acid composition during hepatotoxicity induced by alcohol and heated PUFA Varalakshmi D, Garima S, and Rukkumani R*. J Membrane Biol 247-515-521 2014 2.478
28 Antiproliferative and Apoptotic effects of Sesbania grandiflora Leaves in Human Cancer Cells Sankar P, Kumaravel M, Ramya P, Srividya S, Rukkumani R* Biomed Res Int 1-11 2014 3.411
29 Mechanism of apoptotic induction in human breast cancer cell, MCF-7, by an analog of curcumin in comparison with curcumin - An in vitro and in silico Kumaravel M, Sankar P, Subhashree S, Vivek Kumar S, Larance R, Akhil C Banerjea, Chellakkan S Benson , Mohane SC, Rukkumani R* Chem.Biol.Interact 210:51-63 2013 5.192
30 Hepatoprotective role of wheatgrass on alcohol and ∆PUFA induced oxidative stress in rats Varalakshmi D, Garima S, and Rukkumani R* J. Dietary Suppl. 1-12 2013 2.150
31 Antiproliferative effects of an analog of curcumin in Hep-2 cells: A comparative study with curcumin Kumaravel M, Sankar P, Latha P, and Rukkumani R* Natural Product Commun 8: 183-186 2013 1.242
32 Antihyperglycaemic and antihyperlipidaemic effect of wheatgrass on streptozotocin induced type 2 diabetic rats Garima S, Sankar P, Madhusudhan Rao G and Rukkumani R J. Pharm. Res. 5: 2580-2583 2012 2.669
33 Anticancer effect of an analog of curcumin in human breast cancer cells. Kumaravel, M., Sankar P, and Rukkumani R Eur. Rev. Med. Pharmacol. Sci 16:1900-1907 2012 3.507
34 Protective role of wheatgrass on oxidative stress in streptozotocin induced type 2 diabetic rat Garima S, Charan G, Sankar P, and Rukkumani R Int. J. pharm. pharmaceutic. sci. 4:415-423 2012 1.59
35 Protective role of ferulic acid on carbon tetrachloride-induced hyperlipidemia and histological alterations in experimental rats Srinivasan M , Ram Sudheer A , Rukkumani R, and Menon V.P J. Basic Clin. Physiol. Pharmacol. 24: 59-66 2012 1.69
36 Ferulic acid influences hepatic expression pattern of matrix metalloproteinases during alcohol and PUFA induced toxicity Rukkumani R*, Priyanka A, Sankar P and Menon V.P Eur. Rev. Med. Pharmacol. Sci. 16: 2147-2153. 2012 3.507
37 Protective effects of Sesbania grandiflora on kidney during alcohol and Polyunsaturated fatty acid induced oxidative stress. Kumaravel, M., Karthiga, K., Raviteja, V., Rukkumani, R* Toxicol. Mech. Meth 21, 418-425 2011 2.987
38 Effect of Sesbania grandiflora on Extra Cellular Matrix and Metalloproteinases Expression in Hepatic fibrosis. Keerthana R, Kumaravel M, Raviteja V and Rukkumani R* J. Pharm. Res. 5: 687-690 2011 2.669
39 Protective effects of Phyllanthus amarus on fibrotic markers during alcohol and polyunsaturated fatty acid induced toxicity. Surya Narayanan, B., Latha, P., Rukkumani, R* Toxicol. Mech. Meth. 21, 48-52. 2011 2.987
40 Protective Role of Sesbania grandiflora on Oxidative Stress Status during Alcohol and PUFA Induced Hepatotoxicity. Karthiga, K., Kumaravel, M., Keerthana, R., Rukkumani, R*., Raviteja, V. J. Pharm. Res. 3, 2959-2963. 2010 2.669
41 Effect of Phyllanthus niruri on Alcohol and Polyunsaturated Fatty Acid Induced Oxidative Stress in Liver Mageswari, B., Latha.P, Rukkumani, R*. Int. J. pharm. pharmaceutic. sci. 2, 58-62. 2010 1.59
42 Protective effect of Phyllanthus niruri on alcohol and heated sunflower oil induced hyperlipidemia in Wistar rats Latha, P., Chaitanya, D., Rukkumani, R*. Toxicol. Mech. Meth. 20, 498-503. 2010 2.987
43 Hepatoprotective role of bis-demethoxycurcumin analog on the expression of matrix metalloproteinase induced by alcohol and polyunsaturated fatty acid Rukkumani, R., Subhashree, S. and Menon, V.P Toxicol. Mech. Meth. 20, 252-259. 2010 2.987
44 Recombinant fusion proteins TAT-Mu, Mu, and Mu-Mu mediate efficient non-viral gene delivery. Rukkumani, R., Jennifer, X., Nandini, R., Rao, N.M. and Vijaya, G. J gene Med. 9, 275-286. 2007 4.565
45 Changes in activities of MMP in alcohol and thermally oxidized sunflower oil induced liver damage: NAC antioxidant therapy. Suresh Varma, P., Aruna, K., Rukkumani, R. and Menon, VP. Toxicol. Mech. Meth. 16, 267–274. 2006 2.987
46 FV peptide induces apoptosis in HEp 2 & HeLa cells: an insight into the mechanism of induction. Sri Balasubashini, M., Karthigayan, S., Somasundaram, ST., Balasubramanian, T., Rukkumani, R. and Menon, V.P. J. Carcinogenesis 5, 27. 2006 4.603
47 Role of an Aminothiazole derivative on ethanol induced toxicity. Aruna, K., Rukkumani, R., Suresh Varma, P. and Venugopal P Menon. Toxicol. Mech. Meth. 17, 33–40 2006 2.987
48 Effect of ethanol and thermally oxidized sunflower oil ingestion on phospholipid fatty acid composition in rat liver. Protective role of Cuminum cymin Aruna, K, Rukkumani, R, Suresh Varma, P and Venugopal P. Menon. Ann Nutr Metab 49, 300-303. 2005 3.374
49 Therapeutic role of cuminum cyminum on ethanol and thermally oxidized sunflower oil induced toxicity. Aruna, K., Rukkumani, R., Suresh Varma, P. and Venugopal P Menon. Phytother. Res. 19, 416-421. 2005 5.878
50 Role of Cuminum cyminum on ethanol and heated sunflower oil induced lipid peroxidation. Aruna, K., Rukkumani, R., Suresh Varma, P. and Menon, V.P. J. Herbs Spices Med. Plants. 11, 103-114. 2005 0.788
51 Expression pattern of matrixmetalloproteinase in alcohol and thermally oxidized sunflower oil induced toxicity: Protective role of an Aminothiazole de Aruna, K., Rukkumani, R., Suresh Varma, P. and Menon, V.P. J. Med. Food. 8, 242-245. 2005 2.786
52 Protective effect of N-Acetyl Cysteine in Carbon Tetrachloride-induced hepatotoxicity in rats. Kamalakkannan, N., Rukkumani, R., Aruna, K., Varma, P.S., Viswanathan, P., Rajasekharan, K.N. and Menon, V.P. Iranian J Pharmacol Ther 4, 118-123. 2005 2.599
53 Effect of curcumin and its analogue on lipids in carbon tetrachloride-induced hepatotoxicity: A comparative study. Kamalakkannan, N., Rukkumani, R., Viswanathan, P., Rajasekharan, K.N. and Menon, V.P. Pharmaceut. Biol. 43, 460-466. 2005 3.503
54 Ferulic acid, a natural protector against carbon tetrachloride induced toxicity. Srinivasan, M., Rukkumani, R., Ram Sudheer, A. and Venugopal P. Menon. Fundamental Clin. Pharmacol. 19, 491-496 2005 2.748
55 Comparative effects of curcumin and an analog of curcumin in carbon tetrachloride induced hepatotoxicity in rats. Kamalakkannan, N., Rukkumani, R., Varma, P.S., Viswanathan, P., Rajasekharan, K.N. and Menon, V.P. Basic Clin. Pharmacol. Toxicol. 97, 15-21. 2005 2.651
56 Protective effect of n-acetylcysteine on alcohol and heated sunflower oil induced hyperlipidemia. Suresh Varma, P., Aruna, K., Rukkumani, R. and Menon, V.P. Alc. Res. 9, 266-272. 2005 1.179
57 Comparative effects of curcumin and its analog on alcohol and PUFA induced alterations in circulatory lipid profiles. Rukkumani, R., Aruna, K., Suresh Varma, P. and Menon, V.P. J. Med. Food. 8, 256-260. 2005 2.786
58 Protective role of a novel curcuminoid on alcohol and PUFA Induced hyperlipidemia. Rukkumani, R., Aruna, K., Suresh Varma, P., Viswanathan, P., Rajasekaran, K.N. and Menon, V.P. Toxicol. Mech. Meth. 15, 227-234. 2005 2.987
59 Alcohol and thermally oxidized PUFA induced oxidative stress: Role of n - Acetyl Cysteine. Suresh Varma, P., Aruna, K., Rukkumani, R. and Menon, V.P. Italian J. Biochem. 53, 10-15. 2004 0.390
60 Ferulic acid alleviates lipid peroxidation in diabetic rats. Sribalasubashini, M., Rukkumani, R., Viswanathan, P. and Venugopal P. Menon. Phytother. Res. 18, 310-314. 2004 5.878
61 Influence of a thiazole derivative on ethanol and thermally oxidized sunflower oil induced oxidative stress. Aruna, K., Rukkumani, R., Suresh Varma, P. and Menon, V.P. Fundament. Clin. Pharmacol. 18, 565-571. 2004 2.748
62 Role of an Aminothiazole derivative on ethanol and thermally oxidized sunflower oil induced toxicity. Aruna, K., Rukkumani, R., Suresh Varma, P. and Menon, V.P. Polish J. Pharmacol. 56, 233-240. 2004 2.167
63 Ferulic acid, a natural phenolic antioxidant modulates altered lipid profiles during alcohol and thermally oxidized sunflower oil induced toxicity. Rukkumani, R., Aruna, K., Varma, P.S. and Menon, V.P. J. Nutraceut. Fnl. Med. Food. 4, 119-132. 2004 3.647
64 Influence of ferulic acid on circulatory prooxidant-antioxidant status during alcohol and PUFA induced toxicity. Rukkumani, R., Aruna, K., Varma, P.S. and Menon, V.P. (2004) J. Physiol. Pharmacol. 55, 551-561. 2004 3.011
65 Hepatoprotective role of ferulic acid-a dose dependent study. Rukkumani, R., Aruna K, Suresh Varma P and Menon VP. J Med. Food. 7, 456-461 2004 2.786
66 Curcumin influences hepatic expression patterns of matrix metalloproteinases in liver toxicity. Rukkumani, R., Aruna, K., Suresh Varma, P. and Menon, V.P. Italian J. Biochem. 53, 61-66 2004 0.390
67 Comparative Effects of Curcumin and an Analog of Curcumin on Alcohol and PUFA Induced Oxidative Stress. Rukkumani, R., Aruna, K., Suresh Varma, P. and Menon, V.P. J. Pharm. Pharmaceut. Sci. 7, 274-283 2004 2.042
68 Protective effects of ferulic acid on hyperlipidemic diabetic rats. Sri Balasubashini, M., Rukkumani, R. and Menon, V.P. Acta Diabetol. 40, 118-122. 2003 4.280
69 Protective role of photo-irradiated curcumin on alcohol and thermally oxidised PUFA induced hyperlipidemia. Rukkumani, R. and Venugopal P. Menon Curr. Adv. Atheroscler. Res. 5, 145-156 2003 -
70 Protective effects of curcumin and photoirradiated curcumin on circulatory lipids and lipid peroxidation products in alcohol and polyunsaturated fatty Rukkumani, R., Sri Balasubashini, M. and Venugopal P. Menon Phytother. Res. 17, 925-929. 2003 5.878
71 Comparative effects of curcumin and photo-irradiated curcumin on alcohol-and polyunsaturated fatty acid-induced hyperlipidemia. Rukkumani, R., Sri Balasubashini, M., Viswanathan, P. and Venugopal P. Menon. Pharmacol. Res. 46, 257-264. 2002 7.65

Papers Published in Peer Reviewed Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor

Papers Published in Conference Proceedings

S.No Title Name of the Authors as per the order in Paper Details of Conference Publication Page Nos. Year
1 Effect of Wheatgrass on antioxidant levels during hepatotoxicity induced by alcohol and heated PUFA Varalakshmi D, Rukkumani R. International Conference on Phytochemicals and Disease: Challenges and Future opportunities. - 2013
2 Effect of Wheatgrass on membrane fatty acid composition during hepatotoxicity induced by alcohol and heated PUFA Varalakshmi V, Rukkumani R. International Conference on Bioactive Phytochemicals and Therapeutics - 2013
3 Induction of apoptosis by a curcumin analog in comparison with curcumin in breast cancer cells MCF-7. Kumaravel M, Sankar P, Rukkumani R. . International conference on technological advances in super foods for health care. - 2013
4 Anticarcinogenic effects of an analog of curcumin: a comparative study with curcumin Kumaravel M, Latha P, Sankar P, Rukkumani R. Tenth CMC Winter Symposium 2012 on Cellular and Molecular Medicine: Cancer, Inflammation and Stem Cells (National), Christian Medical College, Vellore - 2012
5 Antiproliferative Activity of Sesbania grandiflora against HEP-2 Cell Line. Sankar P, Kumaravel M, Rukkumani R. Tenth CMC Winter Symposium 2012 on Cellular and Molecular Medicine: Cancer, Inflammation and Stem Cells (National), Christian Medical College, Vellore - 2012
6 Effect of wheatgrass on the oxidative stress in streptozotocin induced type 2 diabetic rats. Garima S, Rukkumani R. National conference on the role of free radicals in health and diseases, Department of Biochemistry, University of Madras - 2012
7 A comparative analysis of curcumin and its analog: an insight on their mechanism of action in cancer Kumaravel M, Sankar P, Rukkumani R. International Conference on Recent Trends in Atherosclerosis and 25th Annual Meeting of ISAR, Biochemistry & Biotechnology, Annamalai University, Chidambaram - 2012
8 In vitro antioxidant and antiproliferative activity of Sesbania grandiflora against Hep-2 cell line. Sankar P, Kumaravel M, Rukkumani R International Conference on Recent Trends in Atherosclerosis and 25th Annual Meeting of ISAR, Biochemistry & Biotechnology, Annamalai University, Chidambaram - 2012
9 Antihyperglycaemic and antihyperlipidaemic effect of wheatgrass on streptozotocin induced type 2 diabetic rats Garima S, sankar P, Kumaravel M, Muddasarul H, Rukkumani R. International Conference on Recent Trends in Atherosclerosis and 25th Annual Meeting of ISAR, Biochemistry & Biotechnology, Annamalai University, Chidambaram - 2012
10 Evaluation of antioxidant and anticarcinogenic activity of wheatgrass and analysis of bioactive constituents, International conference on diabetes mel Garima S, Kumaravel M, Sankar P, Muddasarul H, Rukkumani R. Biochemistry & Biotechnology, Annamalai University, Chidambaram 14 -16 2012

Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Chapters in Books

S.No Title of the Chapters Name of the Authors Title of the Book Publisher Year ISBN No.
1 Nanotechnological Approaches Toward Cancer Chemotherapy Rukkumani R*, Yakhmi JV. Nanostrucutres for Cancer Therapy Elsevier, CA, USA 2017 Print Book & E-Book. ISBN 9780323461443, 9780323461504.
2 Using Microsensors to Promote the Development of Innovative Therapeutic Nanostructures Corinne D, Hamida H, Vincent R, Rukkumani R, Yakhmi JV Nanostrucutres for Novel Therapy – Synthesis, characterization and application Elsevier, CA, USA 2017 Print -9780323461429, e book -9780323461481

Edited Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Ongoing Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Comprehensive Evaluation of the anticancer Efficacy and Safety of Hydrastis canadensis Homeopathic sample EMR-AYUSH 3 Years 58,27,080 2019

Ongoing Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Completed Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Evaluating the Efficacy of an Ortho Hydroxy Substituted Analogue of Curcumin in Reversing Multi Drug Resistance in Human Lung Cancer Cell Line DST-PURSE 3 Years 2,00,000 2014
2 Environmental Jeopardy & Cancer Explosion: A Focus on the Evaluation of Anticancer Potential from Natural Products of Puducherry DSTE 1 year 0.5 2013
3 Cadmium free high luminescence III-V & I-III-VI semiconductors based core-shell nanocrystals as nanoprobes for bio-imaging applications DST 3 years 25 2012
4 Anti-cancer Effect of Disulfiram Loaded Poly [d, l-lactide-co-glycolic acid] (PLGA) Nanoparticles on Hepatocellular carcinoma- An in vitro Study DST 3 years 25 2012
5 Anticarcinogenic effects of an analog of curcumin: Delineating the molecular targets in comparison with curcumin UGC 3 years 11,.2 2010

Completed Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Career Guidance Offered to students

S.No Name of the Scheme No. of Students Competitive Examinations/ Career Counseling No. of Students Passed No. of Students Placed

List of capability enhancement such as Soft skill development, Remedial coaching, Language lab,
Bridge courses, Yoga, Meditation, Personal Counselling and Mentoring etc.,

S.No Name of the Programme/Scheme Date of Implementation No. of Students Enrolled Agencies Involved

Research Guidance - PG

S.No Year Degree No. of Students Awarded Department/Centre
1 2021 M.SC 3 Biochemistry & Molecular Biology
2 2020 M.SC 4 Biochemistry & Molecular Biology
3 2019 M.SC 3 Biochemistry & Molecular Biology
4 2018 M.SC 1 Biochemistry & Molecular Biology
5 2014 M.SC 3 Biochemistry & Molecular Biology
6 2013 M.SC 5 Biochemistry & Molecular Biology
7 2011 M.SC 5 Biochemistry & Molecular Biology
8 2010 M.SC 3 Biochemistry & Molecular Biology
9 2009 M.SC 3 Biochemistry & Molecular Biology

Research Guidance - Ph.D

S.No Student Name Registration Date Registration No. Thesis Title Thesis Submitted Status Thesis Submitted Date Vivavoce Completed Status Date Awarded
1 Shamim Akhtar Sufi 13.09.2012 - Synthesis, Biological Evaluation and Targeted Delivery of an Indole Analogue of Curcumin for Anti- Cancer Therapy YES 04-11-2018 YES 06-08-2019
2 Sankar P. 23.08.2010 - Investigation on the anticarcinogenic potential of sesbania grandiflora leaves YES 11.05.2015 YES 06.05.2016
3 D.Varalakshmi 08.09.2010 - Effect Of Wheatgrass On Alcohol And ∆PUFA Induced Hepatotoxicity YES 11.02.2015 YES 27.01.2016
4 Garima Shakya 02.08.2011 - Pleiotropic Effects Of Wheatgrass On Cancer - A Study To Unravel The Underlying Mechanisms And To Delineate The Potential Molecular Targets YES 13.04.2015 YES 29.02.2016
5 M. Kumaravel 29.07.2011 - Anticarcinogenic Effects Of An Analog Of Curcumin: Delineating The Molecular Targets In Comparison With Curcumin-An In Vitro And In Silico Approach YES 23.01.2015 YES 03.09.2015
6 Muddasarul Hoda 29.08.2011 - Anti-Proliferative & Anti-Metastatic Studies Of Disulfiram & Disulfiram-Loaded Poly [D, L-Lactide-Co-Glycolic Acid] Nanoparticles On Hepatocellular Carcinoma Hep3b Cell Line YES 27.08.2015 YES 25.07.2016

Research Guidance - Post Doctoral

S.No Scholar Name Designation Funding Agency Fellowship Title Year of Joining Year of Completion
1 Dr. Arul Prakash F Postdoctoral Fellow UGC, New Delhi Dr. D.S Kothari Post Doctoral Fellowship 04-07-2019 03-07-2022

Financial assistance availed to attend conferences / workshops and to pay membership fee
of professional bodies during the year

S.No Conference/ workshop attended for which financial support provided Professional body for which membership fee is provided Amount of Support Place From Date To Date Year

E-Lecture Details

S.No E-Lecture Title Development of e-content/e-learning/delivering Member of Editorial Bodies Reviewer/Referee of
Content/Module Title Institution/Platform Year Weblink

Details of Online Education Conducted

S.No Nature of Online Course No. of Sessions Target Group Date

Invited Talks in Conference/Seminar/Workshop/Training Programme

S.No Title of the Paper Conferences/Seminar/Workshop/Training Programme Organized by Whether International / National / State / Regional / College or University Level From To Year
1 Nanotherapy for Cancer International Webinar on Herbal Drug Research and sustainable Health Care Rabiammal Ahamed Maideen College for Women, Tiruvarur. International - - 2021
2 ROR1 Targeted Therpy- A Boon for Metastatic Cancer Treatment Webinar Saveetha Dental College, Saveetha University, Chennai National - - 2021
3 Combating Corona- Where do we stand now? National Webinar Thiru.A.Govindasamy Government arts college, Tindivanam National - - 2020
4 Nano Medicine – A Boon for Cancer Therapy One day seminar Department of Biochemistry, Prince Venkateshwara Arts & Science College College level - - 2019
5 An Effective Targeted Therapy for Metastatic Cancer International Conference on Biotechnological Research and innovation for sustainable development CSIR-IICT, Hyderabad National 22-11-2018 25-11-2018 2018
6 Metabolic Syndrome- Combating the Natural way 31st annual conference and International symposium on ‘Present, Past and Future of atherosclerosis: where do we stand JIPMER, Department of Surgical Gastroenterology, Pathology, Cardio Vascular Thoracic Surgery, and Ca International 11-10-2018 13-10-2018 2018
7 Anti ROR1 Targeted Therapy Effectively Combats Metastasis in Colon Cancer Cell Lines II world cancer congress Raytheon Healthcare International 25-09-2018 26-09-2018 2018
8 Nano Oncology – Combating cancer, the Nano way Seminar Department of Bioinformatics, Pondicherry University, Puducherry University level - - 2017
9 Disulfiram loaded polysorbate 80-stabilized PLGA nanoparticles and their apoptotic & anti-metastatic International Workshop on Advanced Functional Nanomaterials, 4th Edition, 2017 (IWAN 2017) Anna University, Chennai International 22-03-2017 24-03-2017 2017
10 Biochemistry - Career opportunities Biohelix association Inauguration Theivanai Ammal College for Women (Autonomous), Villupuram College level - - 2015
11 Nano medicines for cancer therapy Guest lecture Series Saveetha Dental College, Saveetha University, Chennai University level - - 2015
12 Nanooncology - A New Prospect for the Management of Cancer National seminar on Prospects of Phytonutrients in human welfare Department of Biochemistry, Bharathi Womens College, Chennai National - - 2014
13 Nano Science & Cancer Therapy National seminar on Recent trends in Nano Biotechology, Nano Meet 2013 Department of Nanoscience & Technology, Anna University National 19-09-2013 20-09-2013 2013
14 Peptides for Diagnosis, Prevention and Treatment of Atherosclerosis International Conference on Recent Trends in Atherosclerosis and 25th Annual Meeting of ISAR Department of Biochemistry & Biotechnology, Annamalai University, Chidambaram International 01-09-2012 03-09-2012 2012

Conferences/Seminars Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 International Virtual Conference on Drug Discovery & Translational Research- DDTR -2021 - 2 days International 25-02-2021 26-02-2021 2021
2 3rd National Conference on Drug Discovery & Development – 3D 2020 - Convention cum cultural centre, 2 Days National 06-03-2020 07-03-2020 2020
3 International webinar on COVID -19 – ‘COVINAR’ - 5 days International 20-07-2020 24-07-2020 2020

Workshop Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 Process Behind Drug discovery BRSI Convention cum cultural centre, 1 day University level 03-12-2018 03-12-2018 2018

Administrative Responsibilities in the Government and Quasi Government Agencies

S.No Name of the Position Agency/Organisation Duration Nature of Duties

Affiliation in Academic Bodies/Societies

S.No Name of the Body/Society Nature of Affiliation Year
1 Indian association of Biomedical Sciences (IABMS) Life Member 2015
2 Biotech Research Society, India (BRSI) Life Member 2009
3 Indian Society for Atherosclerosis Research (ISAR) Life Member 2003
4 Society for Free Radical Research (SFRR-India) Life Member 2003
5 Society of Biological Chemists (SBC) Life Member 2003

Participation & Extension Activities (Academic/Administraion)

S.No Name of the Position (Head, Dean, Co-ordinator, Director, etc.,) Duration Nature of Dutites
1 Doctoral committee member - Department of Biochemistry and Molecular Biology, Pondicherry University
2 Board of studies member - Microbiology and School of life science of Pondicherry University and for Theivanai Ammal women’s college, Villupuram
3 Member of Interview panels - Annamalai University and Pondicherry University
4 External examiner for Ph.D - Annamalai University, Anna University, University of Madras, Bharathidasan University, Saveetha University and Central University of Kerala
5 Coordinator of Placement cell and Alumni association - Department of Biochemistry and Molecular Biology, Pondicherry University
6 Reviewer - International and National Journals (PLOS ONE, Toxicology mechanisms and Methods)

Participation & Extension Activities (Co-Curricular)

S.No Name of the Position (NSS, NCC, Warden etc.,) Duration Nature of Dutites

Collaboration with Institution/Industry

S.No Collaborator Name Designation Institution/Industry Type Nature of Collaboration Period of Collaboration Visits to Collaborating
Institution / Industry
Details of Collaborative Research/Teaching
From Date To Date From Date To Date

Faculty Development Programme Attended (Orientation, Refresher, other Short Term Course during the year)

S.No Title of the FDP Organiser Venue Duration From Date To Date Year

Details of Executive Development Prog/Management Development Prog. conducted

S.No Name of the Programme No. of Participants Venue Duration From Date To Date Year Revenue Generated

Participation in IMPESS, IMPRINT, SPARC, STARS, LEAP Programme etc and DSF Funding Programme

S.No IMPRESS/IMPRINT/SPARC/STARS/LEAP/Others Place From Date To Date Year

Enrolment under ARPIT Programme

S.No Name of the Programme Period of the Programme
From Date To Date