SURESH KUMAR. M Associate Professor

Profile Picture

  • Department of Bioinformatics
  • School of Life Sciences
  • suresh.bic@pondiuni.edu.in

Academic Activity

Academic Activity Picture1

Academic Activity Picture2

Educational Qualification (UG,PG & Higher Order)

S.No Degree Subject/Title of thesis University/Board Year of Passing
1 Post doctoral Resear Structural studies on Dengue Virus Non structural Proteins Centre for Biophysical Sciences and Engineering, U 2005
2 Post doctoral Fellow Structural studies on yeast two component signal tranduction University of Oklahoma 2001
3 Ph.D. Structural Studies on Biologically and Medicinally important molecules University of Madras 2000
4 M.Phil Crystallography and Biophysics University of Madras 1994
5 M.Sc Physics University of Madras 1993
6 B.Sc Physics University of Madras 1991

Area of Specializaion

Structural Bioinformatics

Awards / Prizes Conferred

S.No Name / Title of the Award Type Name of the Agency conferred the Award Year of the Award Amount for Cash Award

Teaching Experience

S.No Designation Department/Centre Institution
1 Assistant Professor Centre for Bioinformatics Pondicherry University

Research Experience

S.No Designation Department/Centre Institution Area of Research
1 Research Scholar Dept. of Crystallography and Biophysics University of Madras Crystallography
2 Post doctoral Fellow Centre for Biophysical Sciences and Engineering University of Alabama at Birmingham Structural Biology
3 Visiting Research fellow Institute of structural Biology and Biophysics Forschungszentrum Julich, Germany Structural Biology
4 UGC Raman Fellow Biochemistry and Molecular Biology, Edward Hebert school of Medicine, Uniformed services University of Health Sciences, Bethesda, Maryla Structural Biology

Industry Experience

S.No Designation Company/Corporate Nature of Work

Contribution towards Innovation

S.No Name of the Work/Contribution Specialization Remarks

Patent Details

S.No Title Status Patent Number Year of Award Type Commercialized Status

Papers Published in UGC Approved Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 Molecular Modelling and Biological Evaluation of Phyto-molecules as Potential Activators of Gluconolactone Oxidase (GULO). Sneha Sivadas, Amaresh kumar Mohanty, Sureshkumar Muthuvel, Hannah R.Vasanthi Journal of Biomolecular Structure and Dynamics 10.1080/07391102.2023.218722 2023 4
2 Elucidation of 7,8-dihydroxy flavone in complexing with the oxidative stress-inducing enzymes, its impact on radical quenching and DNA damage: an in s Ishfaq Hassan Mir, Aswathy Sheeja Anilkumar, Shreyoshi Guha, Amaresh Kumar Mohanty, Muthuvel Suresh Kumar, Venugopal Sujatha, Thiyagarajan Ramesh & Chinnasamy Thirunavukkarasu Journal of Biomolecular structure and Dynamics 10.1080/07391102.2023.2218932 2023 4
3 Multi spectroscopic Analysis Decodes the Interaction of Vanadium Nanoparticles with Calf Thymus DNA and Its Anticancer Efect Against Hepatocellular Ca Shreyoshi Guha, Kiruthiga Nanc, Ishfaq Hassan Mir, • Valluru Lokanath, Raghavendar Chikkonda, Venugopal Sujatha, Amaresh Kumar Mohanty, Muthuvel Suresh Kumar, Chinnasamy Thirunavukkarasu Journal of Cluster Science 10.1007/s10876-023-02452-5 2023 3.4
4 Uracil derivatives as HIV-1 capsid protein inhibitors: design, in silico, in vitro and cytotoxicity studies. RSC advances, 12(27), 17466-17480. Ramesh, D., Mohanty, A. K., De, A., Vijayakumar, B. G., Sethumadhavan, A., Muthuvel, S. K., ... & Kannan, T. RSC advances, 12(27), 17466-17480. 12(27), 17466-17480 2022 4

Papers Published in Non UGC Approved Peer Reviewed Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 Insights on the dynamic behavior of protein disulfde isomerase in the solution environment through the SAXS technique Chandrasekar Sanyasi,• Susmida Seni Balakrishnan • Thirunavukkarasu Chinnasamy, • Nagarajan Venugopalan, • Palani Kandavelu, • Renu Batra Saferling, • Suresh Kumar Muthuvel Insilico pharmacology 10.1007/s40203-024-00198-0 2024 2.1
2 Elucidation of escitalopram oxalate and related antidepressants as putative inhibitors of PTP4A3/PRL-3 protein in hepatocellular carcinoma: A multi Ishfaq Hassan Mir, Kankipati Teja Shyam, Susmida Seni Balakrishnan, Muthuvel Suresh Kumar, Thiyagarajan Ramesh, Chinnasamy Thirunavukkarasu Computational Biology and Chemistry 10.1016/j.compbiolchem.2024.108039 2024 3.74
3 Triiodothyronine enhances various forms of kidney-specific Klotho protein and suppresses the Wnt/β-catenin pathway: Insights from in-vitro, in-vivo a Saswat Kumar Mohanty , Amaresh Kumar Mohanty , Muthuvel Suresh Kumar , Kitlangki Suchiang Journal of Cellular Signalling /10.1016/j.cellsig.2024.111214 2024 3.94
4 Molecular modelling and biological evaluation of phyto-molecules as potential activators of gluconolactone oxidase (GULO Sneha Sivadas, Amaresh Kumar Mohanty, Saranga Rajesh, Suresh Kumar Muthuvel & Hannah R. Vasanthi Journal of Biomolecular Structure and Dynamics 10.1080/07391102.2023.2187227 2023 3.39
5 Multi‑spectroscopic Analysis Decodes the Interaction of Vanadium Nanoparticles with Calf Thymus DNA and Its Anticancer Effect Against Hepatocellular Shreyoshi Guha, Kiruthiga Nancy, Ishfaq Hassan Mir, Valluru Lokanatha, Raghavendar Chikkonda, Venugopal Sujatha, Amaresh Kumar Mohanty, Muthuvel Suresh Kumar, Chinnasamy Thirunavukkarasu Journal of Cluster Science 10.1007/s10876-023-02452-5 2023 3.06
6 Elucidation of 7,8-dihydroxy flavone in complexing with the oxidative stress-inducing enzymes, its impact on radical quenching and DNA damage: an in s Ishfaq Hassan Mir, Aswathy Sheeja Anilkumar, Shreyoshi Guha, Amaresh Kumar Mohanty, Muthuvel Suresh Kumar, Venugopal Sujatha, Thiyagarajan Ramesh & Chinnasamy Thirunavukkarasu Journal of Biomolecular structure and Dynamics 10.1080/07391102.2023.2218932 2023 3.39
7 Identification of neo-andrographolide compound targeting NS1 Lys14: an important residue in NS1 activity driving dengue pathogenesis Elakkiya Elumalai and Suresh Kumar Muthuvel Journal of Biomolecular Structure and Dynamics 10.1080/07391102.2022.2068073 2022 3.39
8 Uracil derivatives as HIV-1 capsid protein inhibitors: design, in silico, in vitro and cytotoxicity studies Deepthi Ramesh, Amaresh Kumar Mohanty, Anirban , Balaji Gowrivel Vijayakumar, Aiswarya Sethumadhavan,, Suresh Kumar Muthuvel, Maheswaran Mani and Tharanikkarasu Kannan RSC Advances 10.1039/d2ra02450k 2022 4.03
9 Polymorphisms of T- cell leukemia 1A gene loci are not related to the development of adjuvant letrozole-induced adverse events in breast cancer Gurusamy Umamaheswaran, Dharanipragada Kadambari, Suresh Kumar Muthuvel , Naveena A. N. Kumar, Biswajit Dubashi, Steven Aibor Dkhar, Chandrasekaran Adithan Plos One E 16(3): e0247989 2021 3.24
10 Network Analysis of Dengue NS1 Interacting Core Human Proteins Driving Dengue Pathogenesis Elakkiya Elumalai and Suresh Kumar Muthuvel Current Chemical Biology, 15, 287-300 2021 0.67
11 Effect of mutation of NS2B cofactor residues on Dengue 2 NS2B-NS3 protease complex – an insight to viral replication Amaresh Kumar Mohanty & Muthuvel Suresh Kumar Journal of Biomolecular Structure and Dynamics 10.1080/07391102.2021.2008497 2021 3.39
12 Characterization and Prediction of Dengue Virus Targeting Peptides Based on Combined Amino Acid Composition Descriptors Using Random Forest Algorithm Elakkiya Elumalai and Suresh Kumar Muthuvel Research Square 10.21203/rs.3.rs-1092942/v1 2021 nil
13 First‐in‐class pyrido[2,3‐d]pyrimidine‐2,4(1H,3H)‐diones against leishmaniasis and tuberculosis: Rationale, in vitro, ex vivo studies and me Deepthi Ramesh, Deblina Sarkar, Annu Joji, Monica Singh, Amaresh K. Mohanty, Balaji G Vijayakumar, Mitali Chatterjee, Dharmarajan Sriram, Suresh K. Muthuvel, Tharanikkarasu Kannan Arch Pharm DPhG 10.1002/ardp.202100440 2021 4.613
14 Association of CYP19A1 gene variations with adjuvant letrozole-induced adverse events in South Indian postmenopausal breast cancer cohort expressing h Gurusamy Umamaheswaran, Dharanipragada Kadambari, Suresh Kumar Muthuvel, Sekar Kalaivani, Jaganathan Devi, Solai Elango Damodaran, Suresh Chandra Pradhan, Biswajit Dubashi, Steven Aibor Dkhar, Chandra Breast Cancer Res Treat . 182(1):147-158 2020 3.9
15 Molecular docking and dynamics studies of 4-anilino quinazolines for epidermal growth factor receptor tyrosine kinase to find potent inhibitor Suresh Kumar Muthuvel, Elakkiya Elumalai, Girija K, Hemalatha K J Recept Signal Transduct Res . Oct-Dec 2018; 38(5-6):475-483 2018 1.446
16 Unveiling anticancer potential of glibenclamide: Its synergistic cytotoxicity with doxorubicin on cancer cells Nithyananthan Subramaniyam, Suyavaran Arumugam, Preedia Babu Ezthupurakkal, Subastri Ariraman, Indrani Biswas, Suresh Kumar Muthuvel, Aristatile Balakrishnan, Ghedeir M Alshammari, Thirunavukkarasu Ch J Pharm Biomed Anal . 154:294-30 2018 3.29
17 Insight into the intermolecular recognition mechanism involved in complement component 4 activation through serine protease-trypsin Vikrant Kumar Sinha , Om Prakash Sharma and Muthuvel Suresh Kumar J Biomol Struct Dyn. Feb;36(3):575-589 2018 3.2
18 Molecular evolution and functional divergence of eukaryotic translation initiation factor 2-alpha kinases Krishna KH, Kumar MS Plos one 13(3): e0194335 2018 2.74
19 Anticancer potential of ZnO nanoparticle-ferulic acid conjugate on Huh-7 and HepG2 cells and diethyl nitrosamine induced hepatocellular cancer on Wist Preedia Babu Ezhuthupurakkal, Subastri Ariraman, Suyavaran Arumugam, Nithyananthan Subramaniyan, Suresh Kumar Muthuvel, Premkumar Kumpati, Bharathidasan Rajamani, Thirunavukkarasu Chinnasamy Nanomedicine 14(2):415-428 2018 4.3
20 Exploration of disulfiram dealings with calf thymus DNA using spectroscopic, electrochemical and molecular docking techniques Subastri, A.; Durga, A.; Harikrishna, K.; Sureshkumar, M.; Jeevaratnam, K.; Girish, K. S.; Thirunavukkarasu, C Journal of Luminescence 170, 255-261 2016 2.73
21 Viral Evolved Inhibition Mechanism of the RNA Dependent Protein Kinase PKR's Kinase Domain, a Structural Perspective Krishna KH, Vadlamudi Y, Kumar MS Plos one 11(4): e0153680 2016 2.74
22 Structural exploration of acid sphingomyelinase at different physiological pH through molecular dynamics and docking studies Yallamandayya vadlamudi, Kannan Muthu and Suresh Kumar , M RSC Advances 6, 74859s 2016 3.049
23 Essential proteins and possible therapeutic targets of Wolbachiaendosymbiont and development of FiloBase-a comprehensive drug target database for Lymp Om Prakash Sharma & Muthuvel Suresh Kumar Scientific Reports 6.19842 2016 3.99
24 Design, Synthesis and Biological Evaluation of Novel Phosphorylated Abacavir Derivatives as Antiviral Agents Against Newcastle Disease Virus Infection Suresh K. A., Kadiam C. Venkata Subbaiah, Rayapu Lavanya , Kuruva Chandrasekhar, Naga Raju Chamarti, M. Suresh Kumar & Rajendra Wudayagiri, Lokanatha Valluru Appl Biochem Biotechnol 180(2):361-81. 2016 1.6
25 Synthesis and Antiviral Activity of Novel Phosphorylated Derivatives of Didanosine Against Newcastle Disease Virus in Chicken Karanam Anandan Suresh, Venkata Subbaiah C. Kadiam, Thaslim S. K. Basha, Naga Raju Chamarti, Suresh M. Kumar, Rajendra Wudayagiri and Lokanatha Valluru Arch. Pharm. Chem. Life Sci 349,1–14 2016 2.59
26 Synthesis and biological evaluation of isoindoloisoquinolinone, pyroloisoquinolinone and benzoquinazolinone derivatives as poly(ADP-ribose) polymerase Arumugam Suyavaran, Chitteti Ramamurthy, Ramachandran Mareeswaran, Yagna Viswa Shanthi, Jayaraman Selvakumar, Selvaraj Mangalaraj, Muthuvel Suresh Kumar, Chinnasamy Ramaraj Ramanathan,, Chinnasamy Bioorg Med Chem Feb 1;23(3):488-98 2015 3.03
27 Spectroscopic and molecular docking studies on the interaction of troxerutin with DNA A Subastri, C.H. Ramamurthy, M. Suresh Kumar, V. Sujatha, C. Thirunavukkarasu. A. Suyavarana, R. Mareeswaran, P.Lokeswara Rao, M. Harikrishna Int J Biol Macromol . 78:122-9 2015 5.162
28 Probing the Structural and Conformational Stability of the Wb-iPGM Enzyme and Role of Mn2+ Ions in Their Catalytic Site Sharma, OmPrakash, Hari Krishna Kapa, Suresh Kumar Muthuvel International Journal of Peptide Research and Therapeutics 21 (4), 393-402 2015 1.5
29 Identification of novel tyrosine kinase inhibitors for drug resistant T315I mutant BCR-ABL: a virtual screening and molecular dynamics simulations stu Banavath, H.N., Sharma, O. M. Suresh Kumar & Baskaran, R Scientific Reports .4, 6948 2014 5.007
30 Ethyltrans-12-(pyridin-4-yl)-9,10-ethanoanthracene-11-carboxylate S. Chandrasekar, Prakash Sharma Om, V Srinivasapriyan M. Suresh Kumar C. R. Ramanathan Acta Crystallographica Section E Structure Reports E70,O512 2014 0.35
31 Inhibition of Hyaluronidase by N-acetyl cysteine and Glutathione: Role of Thiol group in Hyaluronan protection Sunitha K, Suresh P, Santhosh MS, Hemshekhar M, Thushara RM, Marathe GK, Thirunavukkarasu C, Kemparaju K, Kumar MS, Girish KS Int J Biol Macromol Apr;55:39-46 2013 2.596
32 Impact of rtI233V mutation in hepatitis B virus polymerase protein and adefovir efficacy: Homology modeling and molecular docking studies. Ismail AM, Sharma OP, Kumar MS, Kannangai R, Abraham P Bioinformation 9(3):121-5 2013 1
33 Virological response and antiviral resistance mutations in chronic hepatitis B subjects experiencing entecavir therapy: An Indian subcontinent perspec Ismail AM, Sharma OP, Kumar MS, Eapen CE, Kannangai R, Abraham P Antiviral Res. 98(2):209-16 2013 3.99
34 Green synthesis and characterization of selenium nanoparticles and its augmented cytotoxicity with doxorubicin on cancer cells Ramamurthy C, Sampath KS, Arunkumar P, Kumar MS, Sujatha V, Premkumar K, Thirunavukkarasu C Bioprocess Biosyst Eng 36(8):1131-9 2013 1.87
35 PepBind: A Comprehensive Database and Computational Tool for Analysis of Protein–peptide Interactions. Arindam Atanu Das, Om Prakash Sharma, Muthuvel Suresh Kumar, Ramadas Krishna, Premendu P. Mathur, Genomics, Genomics Proteomics Bioinformatics 11(4):241-6 2013 1
36 Drug targets for lymphatic filarisis: a bioinformatics approach. Om Prakash Sharma, Yellamandaya Vadalamudi, Arun Gupta Kota, Vikrant Kumar Sinha and Muthuvel Suresh Kumar J Vector Borne Dis 50, September 2013, pp. 155–162 50, pp. 155–162 2013 1.17
37 Cloning, expression of β-1,3-1,4 glucanase from Bacillus subtilis SU40 and the effect of calcium ion on the stability of recombinant enzyme: in vitro Revathi Masilamani, Om Prakash Sharma, Suresh Kumar Muthuvel & Sakthivel Natarajan Bioinformation 9(19): 958-962 2013 1
38 Molecular modeling, Dynamics, and an insight into the structural inhibition of cofactor independent phosphoglycerate mutase isoform 1 from Wuchereria Om Prakash Sharma, Yellamandayya vadlamudi, Qinghua Liao, Birgit strodel and M. Suresh Kumar J Biomol Struct Dyn. 31(7):765-78. 2013 3.2
39 Cloning, expression of b-1,3-1,4 glucanase from Bacillus subtilis SU40 and the effect of calcium ion on the stability of recombinant enzyme: in vitro Revathi Masilamani, Om Prakash Sharma, Suresh Kumar Muthuvel, Sakthivel Natarajan Bioinformation 6;9(19):958-62 2013 1
40 Structural Epitope Database (SEDB): A Web-based Database for the Epitope, and its Intermolecular Interaction Along with the Tertiary Structure Infor Om Prakash Sharma, Arindam Atanu Das, Krishna R, Suresh Kumar M and Premendu P Mathur J Proteomics Bioinform 5:084-089 2012 2.22
41 Evaluation of antioxidant, radical scavenging activity and polyphenolics profile in Solanum torvum L. fruits Ramamurthy CH, Kumar MS, Suyavaran VS, Mareeswaran R, Thirunavukkarasu C. J Food Sci 77(8):C907-13 2012 1.77

Papers Published in Conference Proceedings

S.No Title Name of the Authors as per the order in Paper Details of Conference Publication Page Nos. Year

Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Chapters in Books

S.No Title of the Chapters Name of the Authors Title of the Book Publisher Year ISBN No.

Edited Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.
1 Bioinformatics and Functional Genomics Aditya Kumar, M. Suresh Kumar, Rajabrata Bhuyan, Sumer singh Meena, Venkata Rajesh Yella Wiley India Adaptation 2022 978-93-5464-163-3

Ongoing Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Ongoing Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Completed Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Structure Based Inhibitor Design for Protein Disulfide Isomerase DBT 2011-2014 44764400 2011
2 Structure Based Drug Design for Acidic Sphingomyelinase UGC 2010-2013 1045300 2010

Completed Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Career Guidance Offered to students

S.No Name of the Scheme No. of Students Competitive Examinations/ Career Counseling No. of Students Passed No. of Students Placed

List of capability enhancement such as Soft skill development, Remedial coaching, Language lab,
Bridge courses, Yoga, Meditation, Personal Counselling and Mentoring etc.,

S.No Name of the Programme/Scheme Date of Implementation No. of Students Enrolled Agencies Involved

Research Guidance - PG

S.No Year Degree No. of Students Awarded Department/Centre

Research Guidance - Ph.D

S.No Student Name Registration Date Registration No. Thesis Title Thesis Submitted Status Thesis Submitted Date Vivavoce Completed Status Date Awarded
1 Elakkiya Elumalai 06-06-2016 1600104009 Dengue NS1 Protein A potential Target for Drug Design Structural Bioinformatics Approach YES 06-06-2022 YES 23-12-2022
2 vikrant kuimar sinha 24.07.2012 Activation and Inhibition Study of Human Complement component 4- A structural Perspective YES 25/09/2017 YES 15-10-2018
3 Om Prakash Sharma 27-07-2010 Structural Studies on Macromolecules of Biological and Medicinal Interest YES 9/3/2016 YES 26/10/2016
4 S. Chandrasekar 24.12.2010 Insights on binding mode of ruthenium based anticancer Produrug like compound with serum albumin and the catalyst of oxidative protein folding; a Structural Perspective YES 10/04/2016 YES 12/10/2018
5 yallamandaya Vadlamudi 20.8.2011 Structural and Functional Studies of Acid Sphingomyelinase and its Association with apoptosis and Niemann-pick Disease YES 12/06/2017 YES 07/05/2018
6 Hari Krishna Kappa 30/07/2013 An Evolutionary and Structural Perspective on the Antiviral Acitivity of Protein Kinase R (PKR) YES 12/06/2017 YES 20/12/2018

Research Guidance - Post Doctoral

S.No Scholar Name Designation Funding Agency Fellowship Title Year of Joining Year of Completion

Financial assistance availed to attend conferences / workshops and to pay membership fee
of professional bodies during the year

S.No Conference/ workshop attended for which financial support provided Professional body for which membership fee is provided Amount of Support Place From Date To Date Year

E-Lecture Details

S.No E-Lecture Title Development of e-content/e-learning/delivering Member of Editorial Bodies Reviewer/Referee of
Content/Module Title Institution/Platform Year Weblink

Details of Online Education Conducted

S.No Nature of Online Course No. of Sessions Target Group Date

Invited Talks in Conference/Seminar/Workshop/Training Programme

S.No Title of the Paper Conferences/Seminar/Workshop/Training Programme Organized by Whether International / National / State / Regional / College or University Level From To Year

Conferences/Seminars Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year

Workshop Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year

Administrative Responsibilities in the Government and Quasi Government Agencies

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Affiliation in Academic Bodies/Societies

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Participation & Extension Activities (Academic/Administraion)

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Participation & Extension Activities (Co-Curricular)

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Collaboration with Institution/Industry

S.No Collaborator Name Designation Institution/Industry Type Nature of Collaboration Period of Collaboration Visits to Collaborating
Institution / Industry		 Details of Collaborative Research/Teaching
From Date To Date From Date To Date

Faculty Development Programme Attended (Orientation, Refresher, other Short Term Course during the year)

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Details of Executive Development Prog/Management Development Prog. conducted

S.No Name of the Programme No. of Participants Venue Duration From Date To Date Year Revenue Generated

Participation in IMPESS, IMPRINT, SPARC, STARS, LEAP Programme etc and DSF Funding Programme

S.No IMPRESS/IMPRINT/SPARC/STARS/LEAP/Others Place From Date To Date Year

Enrolment under ARPIT Programme

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From Date To Date