KRISHNA R. Associate Professor

Profile Picture

  • Department of Bioinformatics
  • School of Life Sciences
  • ramadaskr@gmail.com

Academic Activity

Academic Activity Picture1

Academic Activity Picture2

Educational Qualification (UG,PG & Higher Order)

S.No Degree Subject/Title of thesis University/Board Year of Passing
1 Ph.D X-ray studies on biologically important organic compounds University of Madras 2001
2 M.Phil Bio-Physics University of Madras 1995
3 B.Ed Physical science University of Madras 1993
4 M.Sc Bio-Physics University of Madras 1992
5 B.Sc Physics University of Madras 1989

Area of Specializaion

Macromolecular crystallography, structural bioinformatics.

Awards / Prizes Conferred

S.No Name / Title of the Award Type Name of the Agency conferred the Award Year of the Award Amount for Cash Award
1 UGC Major Research award NATIONAL University Grants Commission, Government of India 2014 -

Teaching Experience

S.No Designation Department/Centre Institution
1 Assistant Professor Bioinformatics Pondicherry university
2 Associate Professor Bioinformatics Pondicherry university
3 Professor Bioinformatics Pondicherry university

Research Experience

S.No Designation Department/Centre Institution Area of Research
1 Research Associate Molecular Biophysics Unit Indian Institute of Science (IISc), Bangalore Macromolecular crystallography

Industry Experience

S.No Designation Company/Corporate Nature of Work

Contribution towards Innovation

S.No Name of the Work/Contribution Specialization Remarks

Patent Details

S.No Title Status Patent Number Year of Award Type Commercialized Status

Papers Published in UGC Approved Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 Multi-epitope based vaccine design against Staphylococcus epidermidis: A subtractive proteomics and immunoinformatics approach Sethi, G., Sethi, S., & Krishna, R Microbial Pathogenesis 165, 105484 2022 3.8
2 Pyridine appended 2-hydrazinylthiazole derivatives: design, synthesis, in vitro and in silico antimycobacterial studies Matsa, R., Makam, P., Sethi, G., Thottasseri, A. A., Kizhakkandiyil, A. R.,Ramadas Krishna, & Kannan, T RSC advances 12(29), 18333-18346 2022 4.04
3 Virtual screening assisted discovery of novel natural products to inhibit the catalytic mechanism of Mycobacterium tuberculosis InhA Manikandan Jayaraman, Lakshmanan Loganathan, Karthikeyan Muthusamy, Krishna Ramadas Journal of Molecular Liquids 335(9):116204 2021 6.165
4 Identification and design of a multi-epitope subunit vaccine against the opportunistic pathogen Staphylococcus epidermidis: An immunoinformatics appro Guneswar Sethi, Rinku Polachirakkal Varghese & Ramadas Krishna Journal of Biomolecular Structure and Dynamics NA 2021 5.21
5 Insight into the structural and functional analysis of the impact of missense mutation on cytochrome P450 oxidoreductase Rajalakshmi Kumar, Manikandan Jayaraman, Krishna Ramadas Journal of Molecular Graphics and Modelling 100:107708 2020 2.94
6 An integrated computational investigation to unveil the structural impacts of mutations on the InhA structural gene of Mycobacterium tuberculosis Manikandan Jayaraman, Krishna Ramadas Journal of Molecular Graphics and Modelling 101:107768 2020 2.94
7 Structural insight into conformational dynamics of non-active site mutations in KasA: A Mycobacterium tuberculosis target protein Manikandan Jayaraman Savita Kumari Rajendra Ramadas Krishna Gene 720:144082 2019 2.5
8 Glucovanillin: A potent inhibitor of lipase from Acinetobacter radioresistens Krishna KantGupta, RajuMandal, SharmiliJagtap, KrishnaRamadas Informatics In Medicine Unblocked 10 & 126-133 2018 -
9 Purification, characterization of alkaline cold activelipase from Acinetobacter radioresistens PR8 and development of a new zymography method for li Gupta KK, Jagtap S, Priya R, Ramadas K Protein Pept Lett. 25 (10), 897-907 2018 1.5
10 In silico modeling of Plasmodium falciparum chloroquine resistance transporter protein and biochemical studies suggest its key contribution to chloroq Hiasindh Ashmi Antony, Nishith Saurav Topno, Sathyanarayana N. Gummadi, Devanarayanan Siva Sankar, Ramadas Krishna and Subhash Chandra Parija Acta tropica 189, 2019, 84-93. 2018 2.5
11 Design, synthesis, anticancer properties and insilico evaluation of C(4) N-Heteroaryl 4H-Chromenes H. Surya Prakash Rao, Lakshmi Narayana Adigopula, Gunasundari Ramalingam, Javeed Ahmed Lone and Krishna Ramadas Chemistry Select 3, 13161-13166. 2018 1.5
12 Inhibition of Mur A enzyme in Fusobacterium nucleatum by potential inhibitors indentidiefd through computational and in vitro approaches Amit Kumar, Rajagopalan Saranathan, K.Prashanth, Basant K.Tiwary, Ramadas Krishna RSC Molecular Biosystems 13 & 939-954 2017 2.92
13 Homology Modeling, Molecular Dynamics simulation and essential dynamics on Anopheles gambiae D7r1 Chaynika Goswami, Manikandan Jayaraman, Tamizvathi Bakthavachalam, Guneswar sethi and Ramadas Krishna International Journal of biochemistry and biophysics 5, 3 & 65-77 2017 -
14 A novel guaiane sesquiterpene derivative, guai-2-en-10α-ol from Ulva fasciata Delile inhibits EGFR/PI3K/Akt signaling and induces cytotoxicity Pragna Lakshmi T, Vajravijayan S, Moumita Mondal, Natarajan Sakthivel, Gunasekaran K Molecular and Cellular Biochemistry 438, 1 &123-139 2017 2.057
15 Molecular interaction between human serum albumin (HSA) and phloroglucinol derivative that show selective anti-proliferative potential Moumita Mondal, Pragna Lakshmi T, Ramadas Krishna, Natarajan Sakthivel Journal of Luminescence 192, 990-998 2017 2.732
16 One Pot synthesis of densely substituted pyrazolo [3,4-b]-4,7-Dihydropyridines H.S.P.Rao, Lakshmi Narayana Adigopula,Krishna Ramadas ACS Combinatorial science 19, 5 & 279–285 2017 3.16
17 Mechanistic insights into the activity of Ptf1-p48 (Pancreas Transcription factor 1a): Probing the interactions levels of Ptf1-p48 with E2A-E47 Nishith Saurav Topno, Muthu Kannan and Ramadas Krishna Journal of Biomolecular structure Dynamics 36, 7 &1834-1852. 2017 3.12
18 Identification of natural allosteric inhibitor for Akt1 protein through computational approaches and in vitro evaluation Lakshmi T.Pragna, Amit Kumar, Veena Vijaykumar, Sakthivel Natarajan and Ramadas Krishna International Journal of Biological Macromolecules 96 & 200-213 2017 3.67
19 Molecular interaction of 2,4-diacetylphloroglucinol (DAPG) with human serum albumin (HSA): The spectroscopic, calorimetric and computational investiga Lakshmi Pragna, Moumita Mondal, Ramadas Krishna and Natarajan Sakthivel Spectrochimica Acta Part A: Molecular and Biomolecular spectroscopy 5,183 & 90-102. 2017 2.098
20 Scale-up and inhibitory studies on productivity of lipase from Acinetobacter radioresistens PR8. Gupta KK, Nigam A, Jagtap S, Krishna R Journal of Bioscience and Bioengineering 124,2 &150-155 2017 2.240
21 Structural transition of ETS1 from auto-inhibited to functional state upon association with p16INK4a native and mutated promoter region Kannan Muthu, Manivel Panneerselvam, Nishith Saurav Topno and Krishna Ramadas RSC Advances 6, 15960-15975 2016 3.108
22 Interacting mechanism of ID3 HLH domain towards E2A/E12 transcription factor – An Insight through molecular dynamics and docking approach Nishith Saurav Topno, Kannan Muthu and Krishna Ramadas Biochemistry and Biophysics Report 5, 180-190 2016 -
23 Anti-leukemic, anti-lung, and anti-breast cancer potential of the microbial polyketide 2, 4-diacetylphloroglucinol (DAPG) and its interaction Veena V, Kennedy K, Lakshmi P, Krishna R, Sakthivel N Molecular Cellular Biochemistry 414,1 &47-56 2016 2.057
24 Synthesis, in vitro and in silico anti- proliferative activity of 4-aryl-4H-Chromene A. Parthiban , Kumaravel,M. J.Muthukumaran ,Rukkumani R. R. Krishna, H. Surya Prakash Rao Medicinal Chemistry Research 25, 7 & 1308–1315 2016 1.607
25 Anticancer potential of pyrrole (1, 2, a) pyrazine 1, 4, dione, hexahydro 3-(2-methyl propyl) (PPDHMP) extracted from a new marine bacterium, Staphylo Lalitha P,Veena V, Vidhyapriya P, Lakshmi P, Krishna R, Sakthivel N Apoptosis 21, 5 & 566-77 2016 3.96
26 Target identification in Fusobacterium nucleatum by subtractive genomics approach and enrichment analysis of host-pathogen protein-protein interaction Kumar, A., Thotakura, P. L., Tiwary, B. K., & Krishna, R BMC Microbiology 16, 1 & 1. 84 2016 2.82
27 The quorum sensing molecule N-acyl homoserine lactone produced by Acinetobacter baumannii displays antibacterial and anticancer properties John J, Saranathan R, Adigopula LN, Thamodharan V, Singh SP, Lakshmi TP, CharanTej MA, Rao RS, Krishna R, Rao HS, Prashanth K Biofouling 32, 9 &1029-47 2016 3.08
28 Design, synthesis, in vitro and in silico anti-cancer activity of 4H-chromens with C4-active methine groups A. Parthiban , Kumaravel,M. J.Muthukumaran ,Rukkumani R. R. Krishna, H. Surya Prakash Rao Medicinal Chemistry Research 24, 3 &1226–1240 2015 1.607
29 Structural insights into tumor-specific chaperoning activity of gamma synuclein in protecting estrogen receptor alpha 36 and its role in tamoxifen Manivel Panneerselvam, Kannan Muthu and Krishna Ramadas RSC Molecular Biosystems 11,11 & 2998-3010 2015 2.92
30 Structural perspective of ARHI mediated inhibition of STAT3 signaling: An insight into the inactive to active transition of ARHI and its interaction Kannan Muthu, Manivel Panneerselvam, Nishith Saurav Topno, Manikandan Jayaraman, Krishna Ramadas Cellular Siganlling 27, 4 & 739-55 2015 3.93
31 Synthesis, in vitro and in silico antimalarial activity of 7-chloroquinoline and 4H-chromene conjugates A. Parthiban , J. Muthukumaran , Ashan Manhas , Kumkum Srivastava , R. Krishna, H. Surya Prakash Rao Bioorganic and Medicinal chemistry letters 15;25 & 4657-63 2015 2.42
32 Phenazine-1-carboxamide (PCN) from Pseudomonas sp. Strain PUP6 selectively induced apoptosis in lung (A549) and breast(MDA MB-231) cancer cells by inh Kennedy RK, Veena V, Naik PR, Lakshmi P, Krishna R, Sudharani S, Sakthivel N. Apoptosis 20, 6 &858-68 2015 3.96
33 5-Methyl phenazine-1-carboxylic acid: A novel bioactive metabolite by a rhizosphere soil bacterium that exhibits potent antimicrobial and anticancer R. Kamaraj Kennedy, P.Ravindra Naik, V. Veena, B.S.Lakshmi, Pragna Lakshmi, R.Krishna and N.Sakthivel Chemico-Biological interactions 231, 71-82 2015 2.57
34 Synuclein γ Compromises Spindle Assembly Checkpoint and Renders Resistance to Antimicrotubule Drug Suyu Miao, Kejin Wu, Bo Zhang, Ziyi Weng, Mingjie Zhu, Yunshu Lu, Ramadas Krishna, and Yuenian Eric Shi Molecular Cancer therapeutics 13, 3 & 699-713 2014 5.33
35 Crystallographic and DFT studies on pyrrolo[1,2-c]imidazole scaffolds Manikandan J, Rajarathinam B, Kannan M, Gnanasambandam Vasuki, and Manivel P, Krishna R Journal of crystallography Article ID 369061 2014 -
36 Design, synthesis, molecular docking, and biological evaluation of N-methyl-3-nitro-4-(nitromethyl)-4H-chromen-2-amine derivatives A.Parthiban , J.Muthukumaran, A.Moushmi Priya, S.Jayachandran, R.Krishna, H.Surya Prakash Rao Medicinal Chemistry Research 23 &642–659 2014 1.607
37 Synuclein gamma protects Akt and mTOR and renders tumor resistance to Hsp90 disruption Wei Liang, Shuyu Miao, Bo Zhang, Shaohua He, Chengchao Shou, Panneer S. Manivel, Ramadas Krishna, Yiding Chen, Yuenian Eric Shi nature Oncogene 30, 34(18) &2398-405 2014 8.45
38 Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption Yongfeng Shao, Bingchan Wang, Dorothy Shi, Suyu Miao, Panneerselvam Manivel, Ramadas Krishna, Yiding Chen, Y.Eric Shi Molecular Oncology 8, 8 &1521–1531 2014 5.33
39 Exploring the structural features of Aspartate Trans Carbamoylase (TtATCase) from Thermus thermophilus HB8 through in silico approaches Surekha Kanagarajan, Nachiappan Mutharasappan, Prabhu Dhamodharan, Muthukumaran Jayaraman, Krishna Ramadas, Jeyakanthan Jeyaraman Journal of Biomolecular structure Dynamics 32, 4 &591-601 2013 3.12
40 (Z)-3-(1-Hydroxy-3-oxobut-1-enyl)-6-nitro-2H-chromen-2-one Nishith Saurav Topno,Venkataswamy Tangeti, H. Surya Prakash Rao, R. Krishna Acta Cryst E E69, o284 2013 -
41 Molecular Dynamic Simulations of Tubulin-Human Gamma Synuclein Complex: Structural Insight into the regulatory mechanism involved in inducing resistan Manivel Panneerselvam, Kannan Muthu, Muthukumaran Jayaraman, Upasana Sridharan, Pranitha Jenardhanan and Krishna Ramadas Molecular Biosystems 9, 6 &1470-88 2013 2.92
42 pepbind: A comprehensive database and computational tool for analysis of protein-peptide interactions Arindam Atandu Das, Om Prakash Sharma, M. Suresh Kumar, R. Krishna, P.P. Mathur Genomics, Proteomics and Bioinformatics 11,4 & 241-6. 2013 1.58
43 Synthesis and in silico evaluation of 1N-methyl-1S-methyl-2-nitroethylene (NMSM) derivatives against Alzheimer disease: to understand their interactin M. Kannan, P. Manivel, K. Geetha, J. Muthukumaran, H. Surya Prakash Rao and R. Krishna Journal of chemical biology 5, 4 & 151-166 2012 -
44 A Web-based Database for the Epitope, and its Intermolecular Interaction Along with the Tertiary Structure Information O.P. Sharma, A.A. Das, R. Krishna, M. Suresh Kumar, and P.P. Mathur Journal of Proteomics & Bioinformatics 5: 084-089 2012 1.57
45 6-Ethyl-N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine J. Muthukumaran, A. Parthiban, H. Surya Prakash Rao, R. Krishna Acta Cryst E E68, o180-o181 2012 -
46 Structural insights into interacting mechanism of ID1 protein with an antagonist ID1/3-PA7 and agonist ETS-1 in treatment of ovarian cancer Kannan Muthu, Manivel Panneerselvam, Muthukumaran Jayaraman, Nishith Saurav Topno, Arindam Atanu Das & Ramadas Krishna Journal of Molecular Modeling 18, 11 & 4865-4884 2012 1.507
47 6,8-dichloro-N-methyl-3-nitro-4-(nitromethyl)-4H-chromen-2-amine J. Muthukumaran, A. Parthiban, M. Kannan, H. Surya Prakash Rao and R. Krishna Acta Cryst E67, o898-o899 2011 0.35
48 4-[4-(Diethylamino)phenyl]-N-methyl-3-nitro-4H-chromen-2-amine Muthukumaran, J., Parthiban, A., Manivel, P., Rao, H. S. P. & Krishna, R Acta Cryst E67, o1395-o1396 2011 0.35
49 Advancement in computational analysis methods of plant antifreeze proteins (AFPs): An application towards classification and gene expression studies o J. Muthukumaran, P. Manivel, M. Kannan, J. Jeyakanthan and R. Krishna Journal of Computational Biology and Bioinformatics Research Vol. 3(6), pp. 65-82 2011 1.549
50 6,8-Dichloro-N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine Muthukumaran, J., Parthiban, A., Kannan, M., Rao, H. S. P. & Krishna, R. Acta Cryst E67, o898-o899 2011 0.35
51 A framework for classification of antifreeze proteins in over wintering plants based on their sequence and structural features J. Muthukumaran, P. Manivel, M. Kannan, J. Jeyakanthan and R. Krishna Journal of Bioinformatics and Sequence Analysis 3(4), 70-88 2011 6.937
52 6-Amino-3,4-dimethyl-4-phenyl-2H,4H-pyrano[2,3-c]pyrazole-5-carbonitrile Topno, N. S., Kumaravel, K., Kannan, M., Vasuki, G. & Krishna, R. Acta Cryst E67, o956 2011 0.35
53 1-(2-Naphthyl)-3-phenyl-3-(4,5,6,7-tetrahydro-1,2,3-benzoselenadiazol-4-yl)propan-1-one Muthukumaran, J., Nachiappan, M., Chitra, S., Manisankar, P., Bhattacharya, S., Muthusubramanian, S., Krishna, R. & Jeyakanthan, J. Acta Cryst E67, o2010-o2011 2011 0.35
54 6-Methoxy-N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine Muthukumaran, J., Parthiban, A., Manivel, P., Rao, H. S. P. & Krishna, R. Acta Cryst E67, o1276-o1277 2011 0.35
55 3-(4-Methylphenyl)-1-phenyl-3-(4,5,6,7-tetrahydro-1,2,3-benzoselenadiazol-4-yl)propan-1-one Muthukumaran, J., Nishandhini, M., Chitra, S., Manisankar, P., Bhattacharya, S., Muthusubramanian, S., Krishna, R. & Jeyakanthan, J. Acta Cryst E67, o1660-o1661 2011 0.35
56 4-{(4-Chlorophenyl)[4-(4-methylphenyl)-1,2,3-selenadiazol-5-yl]methyl}-4,5,6,7-tetrahydro-1,2,3-benzoselenadiazole Muthukumaran, J., Nishandhini, M., Chitra, S., Muthusubramanian, S., Manisankar, P., Bhattacharya, S., Krishna, R. & Jeyakanthan, J. Acta Cryst E67, o1421-o1422 2011 0.35
57 Butane-1,4-diyl bis(pyridine-4-carboxylate) Muthukumaran, J., Karthikeyan, S., Satheesh, G., Manimaran, B. & Krishna, R Acta Cryst E67, o1803 2011 0.35
58 2,2'-[Naphthalene-1,5-diylbis(nitrilomethanylylidene)]diphenol Karthikeyan, S., Muthukumaran, J., Krishna, R. & Manimaran, B. Acta Cryst E67, o1765-o1766 2011 0.35
59 An X-ray crystallographic study of N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine Muthukumaran, A.Parthiban, H. Surya Prakash Rao & R. Krishna J Chem Crystallogr 41:1927–1934 2011 0.6
60 Insight into residues involved in the structure and function of the breast cancer associated protein human gamma synuclein Manivel, P., Muthukumaran, J., Kannan, M. & Krishna, R J Mol Model 17:251-263 2011 1.81
61 Molecular dynamics simulation of the Staphylococcus aureus YsxC protein: molecular insights into ribosome assembly and allosteric inhibition of the pr Amit Goyal, Kannan, M., Manivel, P., Anil Kumar Pole & Krishna, R J Mol Model 17, 12, 3129 – 3149 2011 1.81
62 3-Benzyl-6-benzylamino-1-methyl-5-nitro-1,2,3,4-tetrahydropyrimidine Kannan, M., Manivel, P., Sarathbabu, M., Sathishkumar, R., Surya Prakash Rao, H. & Krishna, R Acta Cryst E66, o515 2010 0.35
63 Heptacarbonyl-1j3 C,2j4 C-(4-phenyl-pyridine-1jN)di-l-phenyltellurido-1:2K4Te:Te-dirhenium(I) Vanitha, A., Muthukumaran, J., Krishna, R. & Bala Manimaran Acta Cryst E66, m518-m519 2010 0.35
64 Bis(phenyltellurido-2 Te:Te)bis[tetracarbonylrhenium(I)] J. Muthukumaran, M. Kannan, A. Vanitha, Bala Manimaran and R. Krishna Acta Cryst E66, m558-m559 2010 0.35
65 Ethyl 2-(6-amino-5-cyano-3,4-dimethyl- 2H,4H-pyrano[2,3-c]pyrazol-4-yl)acetate M. Kannan, Kandhasamy Kumaravel, Gnanasambandam Vasuki and R. Krishna Acta Cryst 66(Pt 5):o1242 2010 0.35
66 Ethyl 6-amino-5-cyano-2,4-bis(4-methylphenyl)-4H-pyran-3-carboxylate M. Kannan, Kandhasamy Kumaravel, Gnanasambandam Vasuki and R. Krishna Acta Cryst E66, o2536 2010 0.35
67 Computer-Aided Drug Design of Pyranopyrazoles and Related Compounds for Checkpoint Kinase-1 Rahul Ramtekkar, Kandhasamy Kumarvel, Gnanasambandam Vasuki, K. Sekar, R. Krishna Lett. In Drug. Design 6, 579-584 2009 1.023
68 An Asymmetric Dimer of beta-lactoglobulin in a Low Humidity Crystal Form - Structural Changes that Accompany Partial Dehydration and Protein Action Vijayalakshmi L, Krishna R, Sankaranarayanan R, Vijayan M Prot.Struct.Func.Bio 71, 241-249 2008 3.756
69 Snapshots of RecA Protein Involving Movement of the C-domain and Different Conformations of the DNA-binding Loops: Crystallographic and Comparative An Krishna R, Prabu JR, Manjunath GP, Datta S, Chandra NR, Muniyappa K, Vijayan M J.Mol.Biol 367, 1130-1144 2007 5.469
70 Atomic resolution structure of the double mutant (K53,56M) of bovine pancreatic phospholipase A2 Sekar K, Yogavel M, Gayathri D, Velmurugan D, Krishna R, Poi MJ, Dauter Z, Dauter M, Tsai MD Acta Cryst F. 62, 1-5 2006 1.072
71 Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery Krishna R, Manjunath GP, Kumar P, Surolia A, Chandra NR, Muniyappa K, Vijayan M Nucl.Acids Res 34: 2186-2195 2006 19.16
72 Crystal Structures of Mycobacterium smegmatis RecA and Its Nucleotide Complexes Datta S, Krishna R, Ganesh N, Chandra NR, Muniyappa K, Vijayan M J. Bacteriol 185: 4280-4284 2003 3.49
73 5-Amino-4-(4-dimethylaminophenyl)-2-(4-methoxyphenyl)-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbonitrile Yogavel M, Rajakannan V, Krishna R, Velmurugan, D and Raghukumar V Acta Cryst E59, o200-o202 2003 0.35
74 [6a,16b]-cis-7,7-Dimethyl-6,6a,7,16b-tetrahydrochromeno[4',3':3,4]pyrano[3,2-c]-naphthocoumarin R. Krishna, S. Selvanayagam, M. Yogavel, D. Velmurugan and S. Manikandan Acta Cryst E59,o667-o669 2003 0.35
75 1,2,3,4,4a,12a-Hexahydro-2,5,5-trimethyl-1H-[2]benzopyrano[3,2-c]coumarin R. Krishna, S. Selvanayagam, M. Yogavel, D. Velmurugan, M.Shanmuga sundaram R. Raghunathan, S. Shanmuga Sundara Raj and H.-K. Fun Acta Cryst E59, o808-o809 2003 0.35
76 3-(1-Phenylsulfonyl-2-methylindol-3-ylcarbonyl)propanoic acid R. Krishna, P. G. Aravindan, M. Yogavel, D. Velmurugan, S. Shanmuga Sundara Raj, H.-K. Fun and P. C. Srinivasan Acta Cryst E59, o875-o877 2003 0.35
77 6a,14a-cis-6,6a,7,14a-Tetrahydrochromeno[4',3':3,4]pyrano[3,2-c]coumarin R. Krishna, P. G. Aravindan, M. Yogavel, D. Velmurugan, S. Shanmuga Sundara Raj, H.-K. Fun, M. Shanmuga Sundaram and R. Raghunathan Acta Cryst E59, o1395-o1397 2003 0.35
78 Crystal Structure Analysis of 1',2',3',4'-tetrahydro-1,3-diphenyl-4-chlorospiro[2-pyrazoline-5,2-napthalen]1'one R. Krishna, D. Velmurugan, M. Shanmugasundaram, R. Raghunathan, K Sekar, S. Shanmuga Sundara Raj, H-K. Fun Cryst. Res. Technol 36, 135 2002 1.639
79 Crystal Structure Analysis of 3’5’(dichloro phenyl)-3-ethyl-5-phenyl thio indalo [1,2-e]imidazolidine R. Krishna, D. Velmurugan, S. Shanmuga Sundara Raj, H.-K. Fun, P. C. Srinivasan Cryst. Res. Technol 36, 1295 2001 1.639
80 Crystal Structure Analysis of a New Coumarin Derivative R. Krishna, D. Velmurugan, S. Shanmuga Sundara Raj, H.-K. Fun, M. S. Sundaram, R. Raghunathan Cryst. Res. Technol 36, 11, 1289 – 1294 2001 1.639
81 2,2'-Methylenebis(3-hydroxy-2-cyclohexen-1-one K. SethuSankar, S. Banumathi, R. Krishna and D. Velmurugan Acta Cryst E56, e479-e480 2000 0.35
82 1',2',3',4'-Tetrahydro-1,3-diphenyl-4-p-tolylspiro[2-pyrazoline-5,2'-naphthalen]-1'-one R. Krishna, D. Velmurugan, R. Murugesan, M. Shanmuga Sundaram and R. Raghunathan Acta Cryst C55, 1676-1677 1999 1.184
83 2,4,5-Triphenylspiro[pyrazolidine-3,3'-(4'-flavanone)] R. Krishna, S. Shanmuga Sundara Raj, D. Velmurugan, H.-K. Fun, S. Manikandan and R. Raghunathan Acta Cryst C, 55, 10 1999 1.184
84 2,4,5-Triphenylspiro[pyrazolidine-3,3'-(4'-flavanone)] R. Krishna, S. Shanmuga Sundara Raj, D. Velmurugan, H.-K. Fun, S. Manikandan and R. Raghunathan Acta Cryst C, 55, 10 1999 1.184
85 Bis(indol-3-yl)(4-methylphenyl)methane R. Krishna, D. Velmurugan and S. Shanmuga Sundara Acta Cryst c,55 1999 1.184
86 N-H(indole) intermolecular interactions in 3,3'-benzylidenediindole R. Krishna, D. Velmurugan, G. Babu and P. T. Perumal Acta Cryst C55, 75-78 1999 1.184

Papers Published in Non UGC Approved Peer Reviewed Journals

S.No Title Name of the Authors as per the order in Paper Journal Name Volume, Issue & Page Nos. Year Impact Factor
1 Multi-epitope based vaccine design against Staphylococcus epidermidis: A subtractive proteomics and immunoinformatics approach Sethi, G., Sethi, S., & Krishna, R Microbial Pathogenesis 165, 105484 2022 3.8
2 Pyridine appended 2-hydrazinylthiazole derivatives: design, synthesis, in vitro and in silico antimycobacterial studies Matsa, R., Makam, P., Sethi, G., Thottasseri, A. A., Kizhakkandiyil, A. R.,Ramadas Krishna, & Kannan, T RSC advances 12(29), 18333-18346 2022 4.04
3 Virtual screening assisted discovery of novel natural products to inhibit the catalytic mechanism of Mycobacterium tuberculosis InhA Manikandan Jayaraman, Lakshmanan Loganathan, Karthikeyan Muthusamy, Krishna Ramadas Journal of Molecular Liquid 335(9):116204 2021 6.17
4 Identification and design of a multi-epitope subunit vaccine against the opportunistic pathogen Staphylococcus epidermidis: An immunoinformatics appro Guneswar Sethi, Rinku Polachirakkal Varghese & Ramadas Krishna Journal of Biomolecular Structure and Dynamics 1-13 2021 5.21
5 Insight into the structural and functional analysis of the impact of missense mutation on cytochrome P450 oxidoreductase Rajalakshmi Kumar, Manikandan Jayaraman, Krishna Ramadas Journal of Molecular Graphics and Modelling 100, 107708 2020 2.94
6 An integrated computational investigation to unveil the structural impacts of mutations on the InhA structural gene of Mycobacterium tuberculosis Manikandan Jayaraman, Krishna Ramadas Journal of Molecular Graphics and Modelling 101, 107768 2020 2.94
7 Structural insight into conformational dynamics of non-active site mutations in KasA: A Mycobacterium tuberculosis target protein Manikandan Jayaraman, Savita Kumari Rajendra, Krishna Ramadas Gene Volume 720, 144082 2019 3.69
8 Purification, characterization of alkaline cold activelipase from Acinetobacter radioresistens PR8 and development of a new zymography method for lipa Gupta KK, Jagtap S, Priya R, Ramadas K Protein Pept Lett 25(10):897-907 2018 1.89
9 Glucovanillin: A potent inhibitor of lipase from Acinetobacter radioresistens Krishna Kant Gupta,Raju Mandal, Sharmili Jagtap, Krishna Ramadas Informatics in medicine unlocked Volume 10, Pages 126-133. 2018 3.37
10 In silico modeling of Plasmodium falciparum chloroquine resistance transporter protein and biochemical studies suggest its key contribution to chloroq Hiasindh Ashmi Antony, Nishith Saurav Topno, Sathyanarayana N. Gummadi, Devanarayanan Siva Sankar, Ramadas Krishna and Subhash Chandra Parija Acta tropica 189, 84-93 2018 3.11
11 Design, synthesis, anticancer properties and insilico evaluation of C(4) N-Heteroaryl 4H-Chromenes H. Surya Prakash Rao, Lakshmi Narayana Adigopula, Gunasundari Ramalingam, Javeed Ahmed Lone and Krishna Ramadas Chemistry Select 3,13161-13166 2018 2.31
12 Inhibition of Mur A enzyme in Fusobacterium nucleatum by potential inhibitors identified through computational and in vitro approaches Amit Kumar, Rajagopalan Saranathan, K.Prashanth, Basant K.Tiwary, Ramadas Krishna RSC Molecular Bio systems 13, 939-954 2017 3.74
13 Homology Modeling, Molecular Dynamics simulation and essential dynamics on Anopheles gambiae D7r1 Chaynika Goswami, Manikandan Jayaraman, Tamizvathi Bakthavachalam, Guneswar sethi and Ramadas Krishna International Journal of biochemistry and biophysics 5(3), 65-77 2017 NA
14 A novel guaiane sesquiterpene derivative, guai-2-en-10α-ol from Ulva fasciata Delile inhibits EGFR/PI3K/Akt signaling and induces cytotoxicity in tri Pragna Lakshmi T, Vajravijayan S, Moumita Mondal, Natarajan Sakthivel, Gunasekaran K, Ramadas Krishna Molecular and Cellular Biochemistry 1 – 17 2017 3.84
15 Molecular interaction between human serum albumin (HSA) and phloroglucinol derivative that show selective anti-proliferative potential Moumita Mondal, Pragna Lakshmi T, Ramadas Krishna, Natarajan Sakthivel Journal of Luminescence 192, 990-998 2017 4.17
16 One Pot synthesis of densely substituted pyrazolo [3,4-b]-4,7-Dihydropyridines H.S.P.Rao, Lakshmi Narayana Adigopula,Krishna Ramadas ACS Combinatorial science 19 (5), 279–285 2017 3.9
17 Mechanistic insights into the activity of Ptf1-p48 (Pancreas Transcription factor 1a): Probing the interactions levels of Ptf1-p48 with E2A-E47 (Trans Nishith Saurav Topno, Muthu Kannan and Ramadas Krishna Journal of Biomolecular Structure and Dynamics (7):1834-1852 2017 3.39
18 Identification of natural allosteric inhibitor for Akt1 protein through computational approaches and in vitro evaluation Lakshmi T.Pragna, Amit Kumar, Veena Vijaykumar, Sakthivel Natarajan and Ramadas Krishna International Journal of Biological Macromolecules 200-213 2017 8.02
19 Molecular interaction of 2,4-diacetylphloroglucinol (DAPG) with human serum albumin (HSA): The spectroscopic, calorimetric and computational investiga Lakshmi Pragna, Moumita Mondal, Ramadas Krishna and Natarajan Sakthivel Spectrochimica Acta Part A: Molecular and Biomolecular spectroscopy 183:90-102 2017 4.09
20 Scale-up and inhibitory studies on productivity of lipase from Acinetobacter radioresistens PR8 Gupta KK, Nigam A, Jagtap S, Krishna R J Biosci Bioeng. 124(2):150-155 2017 3.19
21 Structural transition of ETS1 from auto-inhibited to functional state upon association with p16INK4a native and mutated promoter region Kannan Muthu, Manivel Panneerselvam, Nishith Saurav Topno and Krishna Ramadas RSC Advances 6, 15960-15975 2016 4.04
22 Interacting mechanism of ID3 HLH domain towards E2A/E12 transcription factor – An Insight through molecular dynamics and docking approach Nishith Saurav Topno, Kannan Muthu and Krishna Ramadas Biochemistry and Biophysics Report 5, 180-190 2016 2.61
23 Anti-leukemic, anti-lung, and anti-breast cancer potential of the microbial polyketide 2, 4-diacetylphloroglucinol (DAPG) and its interaction with the Veena V, Kennedy K, Lakshmi P, Krishna R, Sakthivel N Mol Cell Biochem 414(1-2):47-56 2016 3.84
24 Synthesis, in vitro and in silico anti- proliferative activity of 4-aryl-4H-Chromene A. Parthiban , Kumaravel,M. J.Muthukumaran ,Rukkumani R. R. Krishna, H. Surya Prakash Rao Med Chem Res 25, 7, 1308–1315 2016 2.35
25 N Anticancer potential of pyrrole (1, 2, a) pyrazine 1, 4, dione, hexahydro 3-(2-methyl propyl) (PPDHMP) extracted from a new marine bacterium, Staphy Lalitha P,Veena V, Vidhyapriya P, Lakshmi P, Krishna R, Sakthivel N Apoptosis 21 (5): 566-77 2016 5.56
26 Target identification in Fusobacterium nucleatum by subtractive genomics approach and enrichment analysis of host-pathogen protein-protein interaction Kumar, A., Thotakura, P. L., Tiwary, B. K., & Krishna, R BMC microbiology 16(1), 1. 84 2016 3.61
27 The quorum sensing molecule N-acyl homoserine lactone produced by Acinetobacter baumannii displays antibacterial and anticancer properties John J, Saranathan R, Adigopula LN, Thamodharan V, Singh SP, Lakshmi TP, CharanTej MA, Rao RS, Krishna R, Rao HS, Prashanth K Biofouling (9):1029-47 2016 3.33
28 Design, synthesis, in vitro and in silico anti-cancer activity of 4H-chromens with C4-active methine groups A. Parthiban , Kumaravel,M. J.Muthukumaran ,Rukkumani R. R. Krishna, H. Surya Prakash Rao Med Chem Res 24, 3, 1226–1240 2015 2.35
29 Structural insights into tumor-specific chaperoning activity of gamma synuclein in protecting estrogen receptor alpha 36 and its role in tamoxifen res Manivel Panneerselvam, Kannan Muthu and Krishna Ramadas Molecular BioSystems 11, 2998-3010 2015 3.74
30 Structural perspective of ARHI mediated inhibition of STAT3 signaling: An insight into the inactive to active transition of ARHI and its interaction w Kannan Muthu, Manivel Panneerselvam, Nishith Saurav Topno, Manikandan Jayaraman, Krishna Ramadas Cellualar Signalling 27, 739-755 2015 4.32
31 Synthesis, in vitro and in silico antimalarial activity of 7-chloroquinoline and 4H-chromene conjugates A. Parthiban , J. Muthukumaran , Ashan Manhas , Kumkum Srivastava , R. Krishna, H. Surya Prakash Rao Bioorganic and Medicinal Chemistry Letters 15;25(20):4657-63 2015 2.82
32 Phenazine-1-carboxamide (PCN) from Pseudomonas sp. Strain PUP6 selectively induced apoptosis in lung (A549) and breast(MDA MB-231) cancer cells by inh Kennedy RK, Veena V, Naik PR, Lakshmi P, Krishna R, Sudharani S, Sakthivel N Apoptosis 20(6):858-68 2015 5.56
33 5-Methhyl phenazine-1-carboxylic acid: A novel bioactive metabolite by a rhizosphere soil bacterium that exhibits potent antimicrobial and anticancer R. Kamaraj Kennedy, P.Ravindra Naik, V. Veena, B.S.Lakshmi, Pragna Lakshmi, R.Krishna and N.Sakthivel Chemico-Biological Interactions 231, 71-82 2015 5.19
34 Synuclein γ Compromises Spindle Assembly Checkpoint and Renders Resistance to Antimicrotubule Drug Suyu Miao, Kejin Wu, Bo Zhang, Ziyi Weng, Mingjie Zhu, Yunshu Lu, Ramadas Krishna, and Yuenian Eric Shi Mol. Cancer Ther 13(3):699-713 2014 6.26
35 Crystallographic and DFT studies on pyrrolo[1,2-c]imidazole scaffolds Manikandan J, Rajarathinam B, Kannan M, Gnanasambandam Vasuki, and Manivel P, Krishna R Journal of crystallography Volume 2014 2014 2.09
36 Design, synthesis, molecular docking, and biological evaluation of N-methyl-3-nitro-4-(nitromethyl)-4H-chromen-2-amine derivatives as potential anti-c A.Parthiban , J.Muthukumaran, A.Moushmi Priya, S.Jayachandran, R.Krishna, H.Surya Prakash Rao Med Chem Res 23:642–659 2014 2.35
37 Synuclein gamma protects Akt and mTOR and renders tumor resistance to Hsp90 disruption Wei Liang, Shuyu Miao, Bo Zhang, Shaohua He, Chengchao Shou, Panneer S. Manivel, Ramadas Krishna, Yiding Chen, Yuenian Eric Shi Nature Oncogene 1-8 2014 8.76
38 Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption Yongfeng Shao, Bingchan Wang, Dorothy Shi, Suyu Miao, Panneerselvam Manivel, Ramadas Krishna, Yiding Chen, Y.Eric Shi Molecular oncology 1-11 2014 7.45
39 Exploring the structural features of Aspartate Trans Carbamoylase (TtATCase) from Thermus thermophilus HB8 through in silico approaches: A potential d Surekha Kanagarajan, Nachiappan Mutharasappan, Prabhu Dhamodharan, Muthukumaran Jayaraman, Krishna Ramadas, Jeyakanthan Jeyaraman J Biomol Struct Dyn 32(4):591-601 2013 3.39
40 PepBind: A comprehensive database and computational tool for analysis of protein-peptide interactions Arindam Atandu Das, Om Prakash Sharma, M. Suresh Kumar, R. Krishna, P.P. Mathur Genomics, Proteomics and Bioinformatics 11(4):241-6 2013 7.69
41 Molecular Dynamic Simulations of Tubulin-Human Gamma Synuclein Complex: Structural Insight into the regulatory mechanism involved in inducing resistan Manivel Panneerselvam, Kannan Muthu, Muthukumaran Jayaraman, Upasana Sridharan, Pranitha Jenardhanan and Krishna Ramadas Molecular BioSystems 9, 1470-148832 2013 3.74
42 Structural insights into interacting mechanism of ID1 protein with an antagonist ID1/3-PA7 and agonist ETS-1 in treatment of ovarian cancer: molecula Kannan Muthu, Manivel Panneerselvam, Muthukumaran Jayaraman, Nishith Saurav Topno, Arindam Atanu Das & Ramadas Krishna J Mol Model Volume 18, Issue 11, pp 4865-4884 2012 1.42
43 Synthesis and in silico evaluation of 1N-methyl-1S-methyl-2-nitroethylene (NMSM) derivatives against Alzheimer disease: to understand their interactin M. Kannan, P. Manivel, K. Geetha, J. Muthukumaran, H. Surya Prakash Rao and R. Krishna Journal of Chemical Biology Volume 5, Issue 4, pp 151-166 2012 3.522
44 Structural Epitope Database (SEDB): A Web-based Database for the Epitope, and its Intermolecular Interaction Along with the Tertiary Structure Informa O.P. Sharma, A.A. Das, R. Krishna, M. Suresh Kumar, and P.P. Mathur J PROTEOMICS BIOINFORM. 5: 084-089 2012 1.57
45 6-Ethyl-N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine J. Muthukumaran, A. Parthiban, H. Surya Prakash Rao, R. Krishna Acta Cryst. E68, o180-o181 2012 0.35
46 (Z)-3-(1-Hydroxy-3-oxobut-1-enyl)-6-nitro-2H-chromen-2-one Nishith Saurav Topno,Venkataswamy Tangeti, H. Surya Prakash Rao, R. Krishna Acta Cryst. E69, o284 2012 0.35
47 6,8-dichloro-N-methyl-3-nitro-4-(nitromethyl)-4H-chromen-2-amine J. Muthukumaran, A. Parthiban, M. Kannan, H. Surya Prakash Rao and R. Krishna Acta Cryst E67, o898-o899 2011 0.35
48 4-[4-(Diethylamino)phenyl]-N-methyl-3-nitro-4H-chromen-2-amine Muthukumaran, J., Parthiban, A., Manivel, P., Rao, H. S. P. & Krishna, R Acta Cryst E67, o1395-o1396 2011 0.35
49 Advancement in computational analysis methods of plant antifreeze proteins (AFPs): An application towards classification and gene expression studies o J. Muthukumaran, P. Manivel, M. Kannan, J. Jeyakanthan and R. Krishna Journal of Computational Biology and Bioinformatics Research Vol. 3(6), pp. 65-82 2011 1.549
50 6,8-Dichloro-N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine Muthukumaran, J., Parthiban, A., Kannan, M., Rao, H. S. P. & Krishna, R. Acta Cryst E67, o898-o899 2011 0.35
51 A framework for classification of antifreeze proteins in over wintering plants based on their sequence and structural features J. Muthukumaran, P. Manivel, M. Kannan, J. Jeyakanthan and R. Krishna Journal of Bioinformatics and Sequence Analysis 3(4), 70-88 2011 6.937
52 6-Amino-3,4-dimethyl-4-phenyl-2H,4H-pyrano[2,3-c]pyrazole-5-carbonitrile Topno, N. S., Kumaravel, K., Kannan, M., Vasuki, G. & Krishna, R. Acta Cryst E67, o956 2011 0.35
53 1-(2-Naphthyl)-3-phenyl-3-(4,5,6,7-tetrahydro-1,2,3-benzoselenadiazol-4-yl)propan-1-one Muthukumaran, J., Nachiappan, M., Chitra, S., Manisankar, P., Bhattacharya, S., Muthusubramanian, S., Krishna, R. & Jeyakanthan, J. Acta Cryst E67, o2010-o2011 2011 0.35
54 6-Methoxy-N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine Muthukumaran, J., Parthiban, A., Manivel, P., Rao, H. S. P. & Krishna, R. Acta Cryst E67, o1276-o1277 2011 0.35
55 3-(4-Methylphenyl)-1-phenyl-3-(4,5,6,7-tetrahydro-1,2,3-benzoselenadiazol-4-yl)propan-1-one Muthukumaran, J., Nishandhini, M., Chitra, S., Manisankar, P., Bhattacharya, S., Muthusubramanian, S., Krishna, R. & Jeyakanthan, J. Acta Cryst E67, o1660-o1661 2011 0.35
56 4-{(4-Chlorophenyl)[4-(4-methylphenyl)-1,2,3-selenadiazol-5-yl]methyl}-4,5,6,7-tetrahydro-1,2,3-benzoselenadiazole Muthukumaran, J., Nishandhini, M., Chitra, S., Muthusubramanian, S., Manisankar, P., Bhattacharya, S., Krishna, R. & Jeyakanthan, J. Acta Cryst E67, o1421-o1422 2011 0.35
57 Butane-1,4-diyl bis(pyridine-4-carboxylate) Muthukumaran, J., Karthikeyan, S., Satheesh, G., Manimaran, B. & Krishna, R Acta Cryst E67, o1803 2011 0.35
58 2,2'-[Naphthalene-1,5-diylbis(nitrilomethanylylidene)]diphenol Karthikeyan, S., Muthukumaran, J., Krishna, R. & Manimaran, B. Acta Cryst E67, o1765-o1766 2011 0.35
59 An X-ray crystallographic study of N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine Muthukumaran, A.Parthiban, H. Surya Prakash Rao & R. Krishna J Chem Crystallogr 41:1927–1934 2011 0.6
60 Insight into residues involved in the structure and function of the breast cancer associated protein human gamma synuclein Manivel, P., Muthukumaran, J., Kannan, M. & Krishna, R J Mol Model 17:251-263 2011 1.81
61 Molecular dynamics simulation of the Staphylococcus aureus YsxC protein: molecular insights into ribosome assembly and allosteric inhibition of the pr Amit Goyal, Kannan, M., Manivel, P., Anil Kumar Pole & Krishna, R J Mol Model 17, 12, 3129 – 3149 2011 1.81
62 3-Benzyl-6-benzylamino-1-methyl-5-nitro-1,2,3,4-tetrahydropyrimidine Kannan, M., Manivel, P., Sarathbabu, M., Sathishkumar, R., Surya Prakash Rao, H. & Krishna, R Acta Cryst E66, o515 2010 0.35
63 Heptacarbonyl-1j3 C,2j4 C-(4-phenyl-pyridine-1jN)di-l-phenyltellurido-1:2K4Te:Te-dirhenium(I) Vanitha, A., Muthukumaran, J., Krishna, R. & Bala Manimaran Acta Cryst E66, m518-m519 2010 0.35
64 Bis(phenyltellurido-2 Te:Te)bis[tetracarbonylrhenium(I)] J. Muthukumaran, M. Kannan, A. Vanitha, Bala Manimaran and R. Krishna Acta Cryst E66, m558-m559 2010 0.35
65 Ethyl 2-(6-amino-5-cyano-3,4-dimethyl- 2H,4H-pyrano[2,3-c]pyrazol-4-yl)acetate M. Kannan, Kandhasamy Kumaravel, Gnanasambandam Vasuki and R. Krishna Acta Cryst 66(Pt 5):o1242 2010 0.35
66 Ethyl 6-amino-5-cyano-2,4-bis(4-methylphenyl)-4H-pyran-3-carboxylate M. Kannan, Kandhasamy Kumaravel, Gnanasambandam Vasuki and R. Krishna Acta Cryst E66, o2536 2010 0.35
67 Computer-Aided Drug Design of Pyranopyrazoles and Related Compounds for Checkpoint Kinase-1 Rahul Ramtekkar, Kandhasamy Kumarvel, Gnanasambandam Vasuki, K. Sekar, R. Krishna Lett. In Drug. Design 6, 579-584 2009 1.023
68 An Asymmetric Dimer of beta-lactoglobulin in a Low Humidity Crystal Form - Structural Changes that Accompany Partial Dehydration and Protein Action Vijayalakshmi L, Krishna R, Sankaranarayanan R, Vijayan M Prot.Struct.Func.Bio 71, 241-249 2008 3.756
69 Snapshots of RecA Protein Involving Movement of the C-domain and Different Conformations of the DNA-binding Loops: Crystallographic and Comparative An Krishna R, Prabu JR, Manjunath GP, Datta S, Chandra NR, Muniyappa K, Vijayan M J.Mol.Biol 367, 1130-1144 2007 5.469
70 Atomic resolution structure of the double mutant (K53,56M) of bovine pancreatic phospholipase A2 Sekar K, Yogavel M, Gayathri D, Velmurugan D, Krishna R, Poi MJ, Dauter Z, Dauter M, Tsai MD Acta Cryst F. 62, 1-5 2006 1.072
71 Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery Krishna R, Manjunath GP, Kumar P, Surolia A, Chandra NR, Muniyappa K, Vijayan M Nucl.Acids Res 34: 2186-2195 2006 19.16
72 Crystal Structures of Mycobacterium smegmatis RecA and Its Nucleotide Complexes Datta S, Krishna R, Ganesh N, Chandra NR, Muniyappa K, Vijayan M J. Bacteriol 185: 4280-4284 2003 3.49
73 5-Amino-4-(4-dimethylaminophenyl)-2-(4-methoxyphenyl)-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbonitrile Yogavel M, Rajakannan V, Krishna R, Velmurugan, D and Raghukumar V Acta Cryst E59, o200-o202 2003 0.35
74 [6a,16b]-cis-7,7-Dimethyl-6,6a,7,16b-tetrahydrochromeno[4',3':3,4]pyrano[3,2-c]-naphthocoumarin R. Krishna, S. Selvanayagam, M. Yogavel, D. Velmurugan and S. Manikandan Acta Cryst E59,o667-o669 2003 0.35
75 1,2,3,4,4a,12a-Hexahydro-2,5,5-trimethyl-1H-[2]benzopyrano[3,2-c]coumarin R. Krishna, S. Selvanayagam, M. Yogavel, D. Velmurugan, M.Shanmuga sundaram R. Raghunathan, S. Shanmuga Sundara Raj and H.-K. Fun Acta Cryst E59, o808-o809 2003 0.35
76 3-(1-Phenylsulfonyl-2-methylindol-3-ylcarbonyl)propanoic acid R. Krishna, P. G. Aravindan, M. Yogavel, D. Velmurugan, S. Shanmuga Sundara Raj, H.-K. Fun and P. C. Srinivasan Acta Cryst E59, o875-o877 2003 0.35
77 6a,14a-cis-6,6a,7,14a-Tetrahydrochromeno[4',3':3,4]pyrano[3,2-c]coumarin R. Krishna, P. G. Aravindan, M. Yogavel, D. Velmurugan, S. Shanmuga Sundara Raj, H.-K. Fun, M. Shanmuga Sundaram and R. Raghunathan Acta Cryst E59, o1395-o1397 2003 0.35
78 Crystal Structure Analysis of 1',2',3',4'-tetrahydro-1,3-diphenyl-4-chlorospiro[2-pyrazoline-5,2-napthalen]1'one R. Krishna, D. Velmurugan, M. Shanmugasundaram, R. Raghunathan, K Sekar, S. Shanmuga Sundara Raj, H-K. Fun Cryst. Res. Technol 36, 135 2002 1.639
79 Crystal Structure Analysis of 3’5’(dichloro phenyl)-3-ethyl-5-phenyl thio indalo [1,2-e]imidazolidine R. Krishna, D. Velmurugan, S. Shanmuga Sundara Raj, H.-K. Fun, P. C. Srinivasan Cryst. Res. Technol 36, 1295 2001 1.639
80 Crystal Structure Analysis of a New Coumarin Derivative R. Krishna, D. Velmurugan, S. Shanmuga Sundara Raj, H.-K. Fun, M. S. Sundaram, R. Raghunathan Cryst. Res. Technol 36, 11, 1289 – 1294 2001 1.639
81 2,2'-Methylenebis(3-hydroxy-2-cyclohexen-1-one K. SethuSankar, S. Banumathi, R. Krishna and D. Velmurugan Acta Cryst E56, e479-e480 2000 0.35
82 1',2',3',4'-Tetrahydro-1,3-diphenyl-4-p-tolylspiro[2-pyrazoline-5,2'-naphthalen]-1'-one R. Krishna, D. Velmurugan, R. Murugesan, M. Shanmuga Sundaram and R. Raghunathan Acta Cryst C55, 1676-1677 1999 1.184
83 2,4,5-Triphenylspiro[pyrazolidine-3,3'-(4'-flavanone)] R. Krishna, S. Shanmuga Sundara Raj, D. Velmurugan, H.-K. Fun, S. Manikandan and R. Raghunathan Acta Cryst C, 55, 10 1999 1.184
84 2,4,5-Triphenylspiro[pyrazolidine-3,3'-(4'-flavanone)] R. Krishna, S. Shanmuga Sundara Raj, D. Velmurugan, H.-K. Fun, S. Manikandan and R. Raghunathan Acta Cryst C, 55, 10 1999 1.184
85 Bis(indol-3-yl)(4-methylphenyl)methane R. Krishna, D. Velmurugan and S. Shanmuga Sundara Acta Cryst c,55 1999 1.184
86 N-H(indole) intermolecular interactions in 3,3'-benzylidenediindole R. Krishna, D. Velmurugan, G. Babu and P. T. Perumal Acta Cryst C55, 75-78 1999 1.184

Papers Published in Conference Proceedings

S.No Title Name of the Authors as per the order in Paper Details of Conference Publication Page Nos. Year
1 The Physical and functional interaction of ID-1 protein with p65 for an activation of NF-kB signalling pathway Manikandan J, Savita Kumari R. Krishna R SBCADD-2018 - 2018
2 Homology Modeling, Molecular Dynamics simulation and essential dynamics on Anopheles gambiae D7r1 Chayanika Goswami, Manikandan J, Guneswar sethi, Krishna R SBCADD-2018 - 2018
3 Purification and characterization of a novel extracellular Protease from marine bacteria isolated from Pseudosubertius andrewsi Guneswar Sethi, Satyanarayan sethi, R.Krishna SBCADD-2018 - 2018
4 Identification of Allosteric Inhibitor for Protein Kinase B (AKT) using Pharmacophore Based Virtual Screening and its Biological Evaluation Pragna Lakshmi T, Moumita Mondal, Natarajan Sakthivel, R. Krishna SBCADD-2016 - 2016
5 Biochemical and structural analysis of ID-3 protein by X-ray crystallography: An important therapeutic target for various cancers Guneswar sethi, Krishna Kant Gupta, Sharad Awasthi, Arunkumar Dhayalan, R.Krishna SBCADD-2016 - 2016
6 Preliminary Crystallization studies of extracellular alkalophilic lipases from acinetibacter radioresistance PR8 Krishna KantGupta, SharmiliJagtap, KrishnaRamadas SBCADD-2015 - 2015
7 Structural Transitions Mediated by HLH Domain of ID3 – An Insight through Molecular Dynamics Approach Nishith Saurav Topno, M. Kannan, Arindam Atanu Das, and R. Krishna International Workshop on Drug Development and Neglected Tropical Infectious Diseases - 2015
8 Lead compound generation using pharmacophore mapping and three dimensional database searching for Abl Kinase in chronic Mycelogenous Leukemia Pragna Lakshmi T and R. Krishna ISRTMSF-2014 - 2014
9 Isolation , Identification of an alkalophilic acinetibacter radioresistance producing extracellular:Partial purification of enzyme Krishna KantGupta, SharmiliJagtap, KrishnaRamadas ICETB-2014 - 2014
10 Crystal structure analysis of bis(6-chloro-4-phenyl-2-p-tolylquinolin-3-yl)sulfane Nishith Saurav Topno, Kannan Muthu and Krishna Ramadas SBCADD-2013 - 2013
11 Insight into the structural mechanism involved in inducing resistance against taxol in cancer cells through molecular docking and dynamic studies P.Manivel, M.Kannan, R.Krishna SBCADD-2013 - 2013
12 The structural insights into interacting mechanism of wild type TPL-2 with P105 and ABIN-2 and onco-TPL-2 in MEK/ERK pathway: To understand TPL-2 mech R.Krishna SBCADD-2013 - 2013
13 Structural insights into interacting mechanism of ID1 protein with an Antagonist ID1/3-PA7 and Agonist ETS-1 in Treatment of Ovarian cancer: Molecular M.Kannan, P. Manivel, R.Krishna SBCADD-2013 - 2012
14 Insight into the structural and functional role of Lymphocyte Antigen 6 complex locus K in cancer: Through molecular modeling and dynamics approach Nishith Saurav Topno, M. Kannan, P. Manivel, J. Muthukumaran and R. Krishna ISRTMSF-2012 - 2012
15 A framework for classification of antifreeze proteins in over wintering plants based on their sequence and structural features Muthukumara. J, R. Krishna ISRTMSF-2012 - 2012
16 Advancement in computational analysis methods of plant antifreeze proteins (AFPs): An application towards classification and gene expression studies o Muthukumara. J, R. Krishna ISRTMSF-2012 - 2012
17 Molecular mechanism of ID1 protein with an antagonist ID1/3-PA7 and agonist ETS-1 in treatment of ovarian cancer: Molecular Docking and dynamics studi M.Kannan, P. Manivel, R.Krishna ISRTMSF-2012 - 2012
18 Insight into the structural and functional role of Lymphocyte Antigen 6 Complex Locus K in cancer: Through molecular modeling and dynamics approach R.Krishna SBCADD-2012 - 2012
19 Crystal structure analysis and biological evaluation of 4H-chromene derivatives through in silico and in vitro studies Muthukumara. J, R. Krishna SBCADD-2012 - 2012
20 Comparative sequence analysis and molecular modeling studies on ice-recrystallization inhibition protein from Hordium vulgare Muthukumara. J, R. Krishna SBCADD-2012 - 2012

Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Chapters in Books

S.No Title of the Chapters Name of the Authors Title of the Book Publisher Year ISBN No.

Edited Books

S.No Title of the Book Name of the Authors as per the order in Book Publisher Year ISBN No.

Ongoing Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Structural characterization of interactions mediated by key proteins in biosynthesis of mycolic acids to design novel leads for treating Tuberculosis Indian Council of Medical Research 3 Years 51 2017
2 Molecular Docking and Dynamics studies to understand the interacting mechanism of oncogenic ID1 protein with its cellular proteins University Grants Commission 2 Years 21 2014

Ongoing Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Completed Projects

S.No Title of the Project Sponsored By Period Sanctioned Amount(Rs. Lakh) Year
1 Comparative genomics study of metabolic pathways to identify drug targets from Fusobacterium nucleatum: Finding out lead molecules using in silico approaches and examining anti-bacterial activity Council of Scientific and Industrial Research (CSIR) 3 Years 16 2013
2 X-ray studies on Protein Crystal: Dehydration/Rehydration studies on Bos taurus – Rhodanese and crystal structure determination of Human gamma synuclein. University Grants Commission 3 Years 12.5 2010
3 Crystal Structure analysis of biologically important macromolecules. Pondicherry University 5 Years 2.5 2007

Completed Consultancy Works

S.No Title of the Consultancy Work Sponsored By Period Sanctioned Amount(Rs. Lakh) Year

Career Guidance Offered to students

S.No Name of the Scheme No. of Students Competitive Examinations/ Career Counseling No. of Students Passed No. of Students Placed

List of capability enhancement such as Soft skill development, Remedial coaching, Language lab,
Bridge courses, Yoga, Meditation, Personal Counselling and Mentoring etc.,

S.No Name of the Programme/Scheme Date of Implementation No. of Students Enrolled Agencies Involved

Research Guidance - PG

S.No Year Degree No. of Students Awarded Department/Centre
1 2019 M.TECH 1 centre for bioinformatics
2 2019 M.SC 3 centre for bioinformatics
3 2018 M.TECH 1 centre for bioinformatics
4 2018 M.SC 3 centre for bioinformatics
5 2017 M.TECH 1 Centre For Bio-Informatics
6 2017 M.SC 3 Centre For Bio-Informatics
7 2016 M.TECH 1 Centre For Bio-Informatics
8 2016 M.SC 3 Centre For Bio-Informatics
9 2015 M.TECH 1 Centre For Bio-Informatics
10 2015 M.SC 3 Centre For Bio-Informatics
11 2014 M.SC 4 Centre For Bio-Informatics
12 2013 M.SC 4 Centre For Bio-Informatics
13 2012 M.SC 4 Centre For Bio-Informatics
14 2011 M.SC 4 Centre For Bio-Informatics
15 2010 M.SC 8 Centre For Bio-Informatics
16 2009 M.SC 8 Centre For Bio-Informatics
17 2008 M.SC 8 Centre For Bio-Informatics

Research Guidance - Ph.D

S.No Student Name Registration Date Registration No. Thesis Title Thesis Submitted Status Thesis Submitted Date Vivavoce Completed Status Date Awarded
1 Guneswar sethi 12-05-2015 1500104001 Development of peptide and multi-epitope based sub-unit vaccine candidate against staphylococcus epidermidis using proteomics and immunoinformatics approach YES 03-06-2022 YES 10-11-2022
2 J.Manikandan 27-08-2014 1400104003 Structural and dynamic insights into the impacts of mutations on the drug targets (InhA and KasA) of Mycobacterium tuberculosis; A computational prospective YES 28-01-2021 YES 25-11-2021
3 Krishna Kant Gupta 24-07-2013 - Production, Purification and Characterization and the inhibitory studies of lipase protein from Acinetobacter radioresistens PR8 YES 01-2018 YES 17-07-2018
4 Adigopula Lakshmi narayana 05-09-2011 - Synthesis, characterization, insilico and invitro evaluation of 4H chromenes, 4,7 dihydropyrozolopyridines and pyrozolopyridines YES 05/2017 YES 26-04-2018
5 Thotakura Prgna Lakshmi 29-08-2012 - Inhibition of AKT and EGFR proteins with natural compounds for breast caner regulation:Computational and invitro studies YES 07/2017 YES 09-04-2018
6 Amit Kumar 30-08-2011 - Role of Fusobacterium nucleatum in colorectal cancer progression, Identification of Druggable targets, Inhibitors through Insilico approaches and inviro inhibition studies on MurA YES 04/2017 YES 27-03-2018
7 Nishit Saurav Topno 30-07-2010 - Mechanistic insight into the interaction of ID-3 with E2A, ptf1-p48 and its implicating role in Pancreatic cancer YES 10/2016 YES 23-02-2018
8 Arindam atanu das 18-08-2011 - Computational analysis of Protein-Peptide Interactions: Development and integration of algorithms, tools and database for qualitative and quantitative characterization of protein-peptide interactions YES 04/2016 YES 16-03-2017
9 P.Manivel 25-10-2010 - Role of intrinsically disordered protein, Gamma synuclein in breast cancer: Insight into its structure and intermolecular dynamics YES 03/2015 YES 30-09-2015
10 M.Kannan 03-09-2009 - Ovarian Cancer regulation by ID-1 and ARHI proteins: A structural perspective YES 02/2015 YES 30-09-2015
11 J.Muthukumaran 24-08-2009 - Crystal structure determination of biologically important organic compounds involved in anti-cancer activity and its evaluation through insilico and invitro methods YES 03/2013 YES 16-09-2013
12 Chandra Jyoti Singha 31-07-2018 1800104005 - NO NO
13 Savita Kumari R 14/06/2018 1800104011 - NO NO
14 Subhashree Subhasmita Nayak 06-08-2019 1900104008 - NO NO
15 Veena Kumari 20-01-2020 1900112001 - NO NO
16 Rahul Mallick 28-01-2021 2000104007 - NO NO
17 Hema Kasthuri R 15-07-2022 2100104001 - NO NO

Research Guidance - Post Doctoral

S.No Scholar Name Designation Funding Agency Fellowship Title Year of Joining Year of Completion

Financial assistance availed to attend conferences / workshops and to pay membership fee
of professional bodies during the year

S.No Conference/ workshop attended for which financial support provided Professional body for which membership fee is provided Amount of Support Place From Date To Date Year

E-Lecture Details

S.No E-Lecture Title Development of e-content/e-learning/delivering Member of Editorial Bodies Reviewer/Referee of
Content/Module Title Institution/Platform Year Weblink

Details of Online Education Conducted

S.No Nature of Online Course No. of Sessions Target Group Date

Invited Talks in Conference/Seminar/Workshop/Training Programme

S.No Title of the Paper Conferences/Seminar/Workshop/Training Programme Organized by Whether International / National / State / Regional / College or University Level From To Year
1 Snapshots of RecA Protein: Comparative analysis of 11 crystal structures Conference Department of Bioinformatics, Alagappa University, Karaikudi-630 003. National 13-06-2012 15-06-2012 2012
2 Molecular dynamics simulation studies on YsxC Protein Conference Centre of Advance Study in Crystallography and Biophysics, University of Madras, Chennai 6-- 025 International 15-08-2012 17-08-2012 2012
3 Anatomy of Protein Structures Conference Department of Statistics, Pondicherry University International 20-11-2012 22-06-2012 2012
4 Anatomy of Protein Structure Conference Madha Engineering college, Kundrathur, Chennai-600 069 National 25-09-2012 26-09-2012 2012

Conferences/Seminars Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year
1 workshop on macromolecular crystallography Pondicherry University Seminar Hall Centre for bioinformatics and one day (18-12-2019) national 18-12-2019 18-12-1019 2019
2 Recent Trends in Macromolecular Crystallography (RTMC-2014) Department of Biotechnology, New Delhi and Pondicherry University Centre For Bioinformatics, Pondicherry University National 12-03-2014 13-03-2014 2014

Workshop Organized

S.No Title of the Programme Sponsors Venue & Duration Whether International / National / State / Regional / College or University Level From To Year

Administrative Responsibilities in the Government and Quasi Government Agencies

S.No Name of the Position Agency/Organisation Duration Nature of Duties

Affiliation in Academic Bodies/Societies

S.No Name of the Body/Society Nature of Affiliation Year

Participation & Extension Activities (Academic/Administraion)

S.No Name of the Position (Head, Dean, Co-ordinator, Director, etc.,) Duration Nature of Dutites
1 Co-ordinator 6 Months Conducting seminar for Research scholars and External experts

Participation & Extension Activities (Co-Curricular)

S.No Name of the Position (NSS, NCC, Warden etc.,) Duration Nature of Dutites
1 Warden-Kabbir Das Hostel 3 years Taking care of Hostel students

Collaboration with Institution/Industry

S.No Collaborator Name Designation Institution/Industry Type Nature of Collaboration Period of Collaboration Visits to Collaborating
Institution / Industry
Details of Collaborative Research/Teaching
From Date To Date From Date To Date
1 Dr. Y. Eric Shi Professor Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China INTERNATIONAL Research collaboration 2012 2015 - - Publication list attached
2 Dr. J.Jeyakanthan Professor and Head Alagappa University, Karaikudi, TamilNadu NATIONAL Research collaboration 2010 Till date - - Publication list attached
3 Dr.K.Gunasekaran Assistant Professor University of Madras NATIONAL Research collaboration 2010 Till date - - Publication list attached
4 Dr.N.Sakthivel Professor Department of Biotechnology, Pondicherry University NATIONAL Research collaboration 2010 Till date - - Publication list attached
5 Dr.K.Prashanth Assistant Professor Department of Biotechnology, Pondicherry University NATIONAL Research collaboration 2010 Till date - - Publication list attached
6 Dr.H.Surya Prakash Rao Professor Department of Chemistry, Pondicherry University NATIONAL Research collaboration 2008 Till date - - Publication list attached

Faculty Development Programme Attended (Orientation, Refresher, other Short Term Course during the year)

S.No Title of the FDP Organiser Venue Duration From Date To Date Year

Details of Executive Development Prog/Management Development Prog. conducted

S.No Name of the Programme No. of Participants Venue Duration From Date To Date Year Revenue Generated

Participation in IMPESS, IMPRINT, SPARC, STARS, LEAP Programme etc and DSF Funding Programme

S.No IMPRESS/IMPRINT/SPARC/STARS/LEAP/Others Place From Date To Date Year

Enrolment under ARPIT Programme

S.No Name of the Programme Period of the Programme
From Date To Date